ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	47/628	152/7206	2.32816058855e-15
ko05033	Nicotine addiction	25/628	56/7206	8.46007773453e-13
ko04080	Neuroactive ligand-receptor interaction	80/628	423/7206	8.44838594931e-12
ko04713	Circadian entrainment	39/628	136/7206	8.53593990911e-12
ko04020	Calcium signaling pathway	57/628	265/7206	7.97661728201e-11
ko04728	Dopaminergic synapse	43/628	185/7206	1.23017426993e-09
ko04727	GABAergic synapse	31/628	110/7206	1.97775704313e-09
ko04720	Long-term potentiation	29/628	99/7206	2.47063380656e-09
ko05031	Amphetamine addiction	27/628	91/7206	6.49730700104e-09
ko05032	Morphine addiction	30/628	110/7206	8.44156890212e-09
ko04921	Oxytocin signaling pathway	44/628	209/7206	2.42020479706e-08
ko04911	Insulin secretion	29/628	117/7206	1.49141220493e-07
ko04070	Phosphatidylinositol signaling system	28/628	112/7206	2.01734263939e-07
ko04024	cAMP signaling pathway	51/628	279/7206	2.16902385686e-07
ko04970	Salivary secretion	25/628	95/7206	3.17656975037e-07
ko04721	Synaptic vesicle cycle	22/628	80/7206	7.17119692669e-07
ko04723	Retrograde endocannabinoid signaling	36/628	175/7206	8.29916650601e-07
ko04725	Cholinergic synapse	32/628	160/7206	6.11664181565e-06
ko04261	Adrenergic signaling in cardiomyocytes	38/628	205/7206	6.54305121764e-06
ko04971	Gastric acid secretion	23/628	98/7206	7.86347997492e-06
ko04925	Aldosterone synthesis and secretion	24/628	105/7206	8.15025951796e-06
ko04745	Phototransduction - fly	13/628	38/7206	1.03100156488e-05
ko05168	Herpes simplex infection	2/628	182/7206	1.41237383543e-05
ko04730	Long-term depression	19/628	78/7206	2.75843272175e-05
ko03040	Spliceosome	1/628	145/7206	3.95366806044e-05
ko04726	Serotonergic synapse	27/628	137/7206	4.36361366567e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	18/628	74/7206	4.56242537917e-05
ko04710	Circadian rhythm	13/628	43/7206	4.62563597009e-05
ko04022	cGMP-PKG signaling pathway	37/628	216/7206	6.41538792423e-05
ko04922	Glucagon signaling pathway	25/628	128/7206	9.78129485671e-05
ko04514	Cell adhesion molecules (CAMs)	25/628	130/7206	0.00012348286278
ko03010	Ribosome	1/628	129/7206	0.000197417536173
ko05322	Systemic lupus erythematosus	2/628	151/7206	0.000202087984665
ko04060	Cytokine-cytokine receptor interaction	4/628	191/7206	0.000227838359185
ko05169	Epstein-Barr virus infection	5/628	206/7206	0.000371265574147
ko05164	Influenza A	3/628	167/7206	0.000401099550709
ko05162	Measles	1/628	120/7206	0.000432718124761
ko05030	Cocaine addiction	16/628	73/7206	0.000433197555141
ko04014	Ras signaling pathway	42/628	279/7206	0.000456748533119
ko04626	Plant-pathogen interaction	7/628	18/7206	0.000499792884189
ko00010	Glycolysis / Gluconeogenesis	16/628	74/7206	0.000509104389691
ko04972	Pancreatic secretion	21/628	111/7206	0.000545558543303
ko04260	Cardiac muscle contraction	19/628	98/7206	0.000801285773261
ko05203	Viral carcinogenesis	10/628	277/7206	0.00102725080143
ko04360	Axon guidance	35/628	233/7206	0.00128174548906
ko04924	Renin secretion	17/628	86/7206	0.00139402818682
ko00562	Inositol phosphate metabolism	17/628	89/7206	0.00180131454435
ko00680	Methane metabolism	9/628	34/7206	0.00196538615174
ko04960	Aldosterone-regulated sodium reabsorption	10/628	41/7206	0.00219183124839
ko04668	TNF signaling pathway	2/628	120/7206	0.00274369112569
ko01230	Biosynthesis of amino acids	16/628	85/7206	0.00282841833253
ko04750	Inflammatory mediator regulation of TRP channels	21/628	122/7206	0.00290654199985
ko05200	Pathways in cancer	26/628	492/7206	0.00370133101195
ko05161	Hepatitis B	5/628	173/7206	0.00371572868728
ko04630	Jak-STAT signaling pathway	3/628	132/7206	0.00449564345575
ko04742	Taste transduction	12/628	61/7206	0.00564197497174
ko05166	HTLV-I infection	13/628	292/7206	0.00576364584691
ko04110	Cell cycle	4/628	145/7206	0.00675878434715
ko04350	TGF-beta signaling pathway	2/628	103/7206	0.00783402683045
ko04010	MAPK signaling pathway	42/628	321/7206	0.0080806822311
ko00051	Fructose and mannose metabolism	9/628	42/7206	0.0089215179343
ko04120	Ubiquitin mediated proteolysis	4/628	138/7206	0.00924230897054
ko04621	NOD-like receptor signaling pathway	5/628	157/7206	0.00937829384621
ko04072	Phospholipase D signaling pathway	28/628	197/7206	0.00971346940682
ko04964	Proximal tubule bicarbonate reclamation	7/628	29/7206	0.0105380844409
ko04620	Toll-like receptor signaling pathway	2/628	100/7206	0.0112696079112
ko05202	Transcriptional misregulation in cancer	7/628	188/7206	0.0119947363749
ko04114	Oocyte meiosis	21/628	139/7206	0.0137556702292
ko03008	Ribosome biogenesis in eukaryotes	1/628	79/7206	0.0138314795433
ko04740	Olfactory transduction	14/628	80/7206	0.0142582839897
ko05010	Alzheimer's disease	28/628	202/7206	0.0152707058289
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/628	59/7206	0.0163385907311
ko04550	Signaling pathways regulating pluripotency of stem cells	6/628	165/7206	0.0166889493298
ko03013	RNA transport	6/628	166/7206	0.0168579644785
ko04978	Mineral absorption	8/628	40/7206	0.0200650151638
ko05206	MicroRNAs in cancer	7/628	177/7206	0.0208908459426
ko04966	Collecting duct acid secretion	6/628	26/7206	0.0217411802757
ko05110	Vibrio cholerae infection	11/628	63/7206	0.0221011463786
ko05222	Small cell lung cancer	2/628	89/7206	0.022518749166
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/628	14/7206	0.0282017789374
ko04150	mTOR signaling pathway	8/628	184/7206	0.0331017098609
ko04141	Protein processing in endoplasmic reticulum	8/628	184/7206	0.0331017098609
ko04744	Phototransduction	7/628	36/7206	0.0332080926239
ko04510	Focal adhesion	12/628	240/7206	0.0358524003758
ko04330	Notch signaling pathway	1/628	62/7206	0.0407966726323
ko04622	RIG-I-like receptor signaling pathway	1/628	62/7206	0.0407966726323
ko04217	Necroptosis	8/628	178/7206	0.042775141999
ko04210	Apoptosis	8/628	180/7206	0.0432511779177
ko04064	NF-kappa B signaling pathway	3/628	96/7206	0.045395628866
ko05212	Pancreatic cancer	2/628	83/7206	0.0466056022324