ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	156/896	423/7206	6.03312566016e-41
ko04724	Glutamatergic synapse	71/896	152/7206	5.97672012691e-26
ko05033	Nicotine addiction	39/896	56/7206	2.79166611004e-23
ko04713	Circadian entrainment	57/896	136/7206	3.03534979402e-18
ko05032	Morphine addiction	49/896	110/7206	3.66360702678e-17
ko04728	Dopaminergic synapse	66/896	185/7206	1.30289289523e-16
ko04727	GABAergic synapse	48/896	110/7206	2.14978604559e-16
ko04725	Cholinergic synapse	58/896	160/7206	4.32931822778e-15
ko04723	Retrograde endocannabinoid signaling	60/896	175/7206	2.69025926703e-14
ko04911	Insulin secretion	45/896	117/7206	4.89232995704e-13
ko04726	Serotonergic synapse	48/896	137/7206	4.54368509102e-12
ko04721	Synaptic vesicle cycle	34/896	80/7206	1.37484463721e-11
ko04360	Axon guidance	66/896	233/7206	4.35471711497e-11
ko04024	cAMP signaling pathway	72/896	279/7206	7.00211046813e-10
ko04020	Calcium signaling pathway	67/896	265/7206	5.78804139678e-09
ko05031	Amphetamine addiction	32/896	91/7206	1.59144730638e-08
ko04742	Taste transduction	25/896	61/7206	1.75918179804e-08
ko04514	Cell adhesion molecules (CAMs)	39/896	130/7206	9.51392313487e-08
ko03040	Spliceosome	1/896	145/7206	1.4293260481e-07
ko04921	Oxytocin signaling pathway	53/896	209/7206	1.94631950656e-07
ko04970	Salivary secretion	30/896	95/7206	6.66359973357e-07
ko05030	Cocaine addiction	25/896	73/7206	1.05579852457e-06
ko04120	Ubiquitin mediated proteolysis	2/896	138/7206	3.13179582712e-06
ko05164	Influenza A	4/896	167/7206	4.60075753181e-06
ko05322	Systemic lupus erythematosus	3/896	151/7206	4.84918366198e-06
ko04261	Adrenergic signaling in cardiomyocytes	48/896	205/7206	1.24375517385e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/896	74/7206	1.78540897219e-05
ko04720	Long-term potentiation	28/896	99/7206	1.8519260676e-05
ko03013	RNA transport	5/896	166/7206	3.74114677307e-05
ko05203	Viral carcinogenesis	14/896	277/7206	3.81237767154e-05
ko04925	Aldosterone synthesis and secretion	28/896	105/7206	6.70294923402e-05
ko04730	Long-term depression	22/896	78/7206	0.000168155160639
ko04972	Pancreatic secretion	28/896	111/7206	0.000206307404772
ko04744	Phototransduction	13/896	36/7206	0.000229173128523
ko04141	Protein processing in endoplasmic reticulum	8/896	184/7206	0.000253306175506
ko04971	Gastric acid secretion	25/896	98/7206	0.000316934313908
ko05168	Herpes simplex infection	8/896	182/7206	0.000355625082682
ko04022	cGMP-PKG signaling pathway	45/896	216/7206	0.000479836354221
ko03008	Ribosome biogenesis in eukaryotes	1/896	79/7206	0.000493021382126
ko04010	MAPK signaling pathway	61/896	321/7206	0.000512900091527
ko04540	Gap junction	30/896	128/7206	0.000578689388644
ko04621	NOD-like receptor signaling pathway	7/896	157/7206	0.000894248836696
ko05162	Measles	4/896	120/7206	0.00109850219923
ko04060	Cytokine-cytokine receptor interaction	10/896	191/7206	0.00116359526163
ko04014	Ras signaling pathway	53/896	279/7206	0.00153641105057
ko04740	Olfactory transduction	20/896	80/7206	0.00176145505619
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/896	59/7206	0.00211591428958
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/896	182/7206	0.00283614805289
ko00561	Glycerolipid metabolism	1/896	63/7206	0.00358451903739
ko01524	Platinum drug resistance	2/896	76/7206	0.00468807427652
ko04612	Antigen processing and presentation	2/896	77/7206	0.00473858220576
ko05169	Epstein-Barr virus infection	13/896	206/7206	0.00510608565533
ko04745	Phototransduction - fly	11/896	38/7206	0.00515709999816
ko04146	Peroxisome	3/896	89/7206	0.0054181377984
ko05016	Huntington's disease	14/896	215/7206	0.00606744676401
ko04916	Melanogenesis	29/896	142/7206	0.00646683984912
ko04964	Proximal tubule bicarbonate reclamation	9/896	29/7206	0.00674421509044
ko04974	Protein digestion and absorption	21/896	96/7206	0.00777926166914
ko04217	Necroptosis	11/896	178/7206	0.00789351918408
ko00564	Glycerophospholipid metabolism	4/896	99/7206	0.00824596276834
ko04976	Bile secretion	18/896	80/7206	0.00998689110819
ko04630	Jak-STAT signaling pathway	7/896	132/7206	0.0106556046745
ko04064	NF-kappa B signaling pathway	4/896	96/7206	0.0115663290324
ko04011	MAPK signaling pathway - yeast	1/896	53/7206	0.0116233251368
ko04260	Cardiac muscle contraction	21/896	98/7206	0.0124145666595
ko05166	HTLV-I infection	23/896	292/7206	0.0142880542871
ko05205	Proteoglycans in cancer	21/896	271/7206	0.0146182898833
ko04610	Complement and coagulation cascades	3/896	79/7206	0.0152854548749
ko04750	Inflammatory mediator regulation of TRP channels	24/896	122/7206	0.0185628300673
ko04930	Type II diabetes mellitus	13/896	54/7206	0.0196497795964
ko04218	Cellular senescence	12/896	177/7206	0.020384064691
ko04110	Cell cycle	9/896	145/7206	0.0212113069334
ko05133	Pertussis	4/896	87/7206	0.0214380942265
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/896	14/7206	0.0224358127513
ko04142	Lysosome	10/896	151/7206	0.0248330154102
ko00260	Glycine, serine and threonine metabolism	1/896	48/7206	0.0255986556005
ko00240	Pyrimidine metabolism	6/896	110/7206	0.0274135657852
ko04962	Vasopressin-regulated water reabsorption	13/896	58/7206	0.0275071453489
ko04210	Apoptosis	13/896	180/7206	0.029518140576
ko04960	Aldosterone-regulated sodium reabsorption	10/896	41/7206	0.0297982633173
ko01200	Carbon metabolism	8/896	128/7206	0.030068402492
ko00310	Lysine degradation	3/896	73/7206	0.0303356039101
ko03022	Basal transcription factors	1/896	44/7206	0.0371746292155
ko00620	Pyruvate metabolism	1/896	46/7206	0.0391957206691
ko03420	Nucleotide excision repair	1/896	46/7206	0.0391957206691
ko05145	Toxoplasmosis	8/896	126/7206	0.0397209561059
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/896	79/7206	0.0398389262102
ko04015	Rap1 signaling pathway	46/896	278/7206	0.040884702609
ko04140	Autophagy - animal	12/896	164/7206	0.0419622824577
ko05418	Fluid shear stress and atherosclerosis	13/896	173/7206	0.04708445736
ko05161	Hepatitis B	13/896	173/7206	0.04708445736
ko04924	Renin secretion	17/896	86/7206	0.0471728738796
ko04918	Thyroid hormone synthesis	17/896	86/7206	0.0471728738796
ko04620	Toll-like receptor signaling pathway	6/896	100/7206	0.0472738749668