ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	176/1084	423/7206	8.48320066449e-43
ko04724	Glutamatergic synapse	81/1084	152/7206	1.04032859804e-28
ko05033	Nicotine addiction	44/1084	56/7206	2.65655925013e-26
ko05032	Morphine addiction	61/1084	110/7206	4.50258739158e-23
ko04713	Circadian entrainment	68/1084	136/7206	3.62346291756e-22
ko04727	GABAergic synapse	58/1084	110/7206	1.55231573061e-20
ko04728	Dopaminergic synapse	77/1084	185/7206	7.49112164148e-19
ko04024	cAMP signaling pathway	96/1084	279/7206	1.74816599783e-16
ko04020	Calcium signaling pathway	90/1084	265/7206	5.36529284335e-15
ko04725	Cholinergic synapse	64/1084	160/7206	7.46630217627e-15
ko04723	Retrograde endocannabinoid signaling	67/1084	175/7206	2.2106131567e-14
ko04721	Synaptic vesicle cycle	40/1084	80/7206	1.55196354756e-13
ko04921	Oxytocin signaling pathway	73/1084	209/7206	3.94660666721e-13
ko04911	Insulin secretion	47/1084	117/7206	2.56692343746e-11
ko04742	Taste transduction	31/1084	61/7206	5.10006467224e-11
ko04726	Serotonergic synapse	51/1084	137/7206	1.01953192045e-10
ko04744	Phototransduction	22/1084	36/7206	2.99119937366e-10
ko05031	Amphetamine addiction	38/1084	91/7206	5.582343283e-10
ko04261	Adrenergic signaling in cardiomyocytes	63/1084	205/7206	7.34174428057e-09
ko04720	Long-term potentiation	38/1084	99/7206	9.51932412851e-09
ko03010	Ribosome	1/1084	129/7206	2.84463679778e-08
ko04970	Salivary secretion	36/1084	95/7206	3.46002052582e-08
ko03040	Spliceosome	3/1084	145/7206	2.28975365485e-07
ko04925	Aldosterone synthesis and secretion	36/1084	105/7206	6.6727181304e-07
ko05322	Systemic lupus erythematosus	4/1084	151/7206	7.54071753539e-07
ko04070	Phosphatidylinositol signaling system	37/1084	112/7206	1.47179054991e-06
ko05203	Viral carcinogenesis	16/1084	277/7206	1.83502387784e-06
ko04072	Phospholipase D signaling pathway	55/1084	197/7206	2.35819023418e-06
ko04022	cGMP-PKG signaling pathway	59/1084	216/7206	2.47104646827e-06
ko04060	Cytokine-cytokine receptor interaction	8/1084	191/7206	2.61473183952e-06
ko05030	Cocaine addiction	27/1084	73/7206	3.0905429543e-06
ko04971	Gastric acid secretion	33/1084	98/7206	4.83189175164e-06
ko03013	RNA transport	7/1084	166/7206	1.31869060109e-05
ko04730	Long-term depression	27/1084	78/7206	1.5781270038e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1084	74/7206	1.92128820078e-05
ko05168	Herpes simplex infection	9/1084	182/7206	2.14380416385e-05
ko04010	MAPK signaling pathway	76/1084	321/7206	2.90539281571e-05
ko04745	Phototransduction - fly	16/1084	38/7206	5.16174133295e-05
ko04710	Circadian rhythm	17/1084	43/7206	7.89812411152e-05
ko04740	Olfactory transduction	26/1084	80/7206	9.55507778642e-05
ko04014	Ras signaling pathway	66/1084	279/7206	0.000108522386739
ko04110	Cell cycle	7/1084	145/7206	0.000144861240822
ko04621	NOD-like receptor signaling pathway	8/1084	157/7206	0.000158020958513
ko04514	Cell adhesion molecules (CAMs)	36/1084	130/7206	0.000166429026237
ko05169	Epstein-Barr virus infection	14/1084	206/7206	0.000340718287551
ko05164	Influenza A	10/1084	167/7206	0.000402294994322
ko03008	Ribosome biogenesis in eukaryotes	2/1084	79/7206	0.000414324928481
ko04750	Inflammatory mediator regulation of TRP channels	33/1084	122/7206	0.000492758259737
ko05140	Leishmaniasis	2/1084	75/7206	0.000911985100331
ko04120	Ubiquitin mediated proteolysis	8/1084	138/7206	0.00105719705701
ko04972	Pancreatic secretion	30/1084	111/7206	0.00110522580907
ko04915	Estrogen signaling pathway	34/1084	131/7206	0.00115763399858
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1084	79/7206	0.00125467937597
ko04922	Glucagon signaling pathway	33/1084	128/7206	0.00158324047387
ko05161	Hepatitis B	12/1084	173/7206	0.00164503398723
ko04371	Apelin signaling pathway	42/1084	177/7206	0.00190693099451
ko04350	TGF-beta signaling pathway	5/1084	103/7206	0.00197021158433
ko04630	Jak-STAT signaling pathway	8/1084	132/7206	0.00197454186372
ko04923	Regulation of lipolysis in adipocytes	22/1084	77/7206	0.00200591652532
ko04260	Cardiac muscle contraction	26/1084	98/7206	0.00262224490822
ko04360	Axon guidance	52/1084	233/7206	0.00272546150625
ko04626	Plant-pathogen interaction	8/1084	18/7206	0.00273368105032
ko05162	Measles	7/1084	120/7206	0.00277659521361
ko04966	Collecting duct acid secretion	10/1084	26/7206	0.00302595173021
ko04612	Antigen processing and presentation	3/1084	77/7206	0.00338738226142
ko04064	NF-kappa B signaling pathway	5/1084	96/7206	0.00380278826645
ko00562	Inositol phosphate metabolism	24/1084	89/7206	0.00396390999483
ko05414	Dilated cardiomyopathy	28/1084	112/7206	0.00490337230975
ko05205	Proteoglycans in cancer	25/1084	271/7206	0.0053963925976
ko04924	Renin secretion	23/1084	86/7206	0.00552707108609
ko04540	Gap junction	31/1084	128/7206	0.00568906359988
ko04930	Type II diabetes mellitus	16/1084	54/7206	0.006151733985
ko04330	Notch signaling pathway	2/1084	62/7206	0.00631473986387
ko04141	Protein processing in endoplasmic reticulum	15/1084	184/7206	0.00637472505372
ko04214	Apoptosis - fly	3/1084	72/7206	0.00705224587159
ko05219	Bladder cancer	1/1084	48/7206	0.00714890147582
ko05166	HTLV-I infection	28/1084	292/7206	0.00726863162101
ko04964	Proximal tubule bicarbonate reclamation	10/1084	29/7206	0.00745326943116
ko04610	Complement and coagulation cascades	4/1084	79/7206	0.0103327178952
ko03022	Basal transcription factors	1/1084	44/7206	0.0104885360177
ko04270	Vascular smooth muscle contraction	35/1084	154/7206	0.0115860459764
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1084	14/7206	0.0116099933152
ko05110	Vibrio cholerae infection	17/1084	63/7206	0.0123488645734
ko05321	Inflammatory bowel disease (IBD)	2/1084	56/7206	0.0130630403917
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1084	100/7206	0.016106718229
ko04976	Bile secretion	20/1084	80/7206	0.0175307224524
ko04622	RIG-I-like receptor signaling pathway	3/1084	62/7206	0.0195671664287
ko05231	Choline metabolism in cancer	30/1084	134/7206	0.0202777414626
ko04015	Rap1 signaling pathway	56/1084	278/7206	0.0204769933363
ko00240	Pyrimidine metabolism	8/1084	110/7206	0.0213525046536
ko04146	Peroxisome	6/1084	89/7206	0.0246406955273
ko05206	MicroRNAs in cancer	16/1084	177/7206	0.0247192388919
ko05016	Huntington's disease	21/1084	215/7206	0.0258525182097
ko04973	Carbohydrate digestion and absorption	12/1084	42/7206	0.0267002988121
ko04510	Focal adhesion	24/1084	240/7206	0.0270740037225
ko04550	Signaling pathways regulating pluripotency of stem cells	15/1084	165/7206	0.0276007836567
ko04658	Th1 and Th2 cell differentiation	7/1084	96/7206	0.0305178231614
ko00230	Purine metabolism	40/1084	194/7206	0.0322562238491
ko04657	IL-17 signaling pathway	6/1084	87/7206	0.0333685210743
ko05133	Pertussis	6/1084	87/7206	0.0333685210743
ko04210	Apoptosis	17/1084	180/7206	0.0341655689008
ko04711	Circadian rhythm - fly	5/1084	13/7206	0.0344116367564
ko03410	Base excision repair	1/1084	38/7206	0.0363554437782
ko03420	Nucleotide excision repair	2/1084	46/7206	0.0380764319878
ko05217	Basal cell carcinoma	4/1084	68/7206	0.0385773126666
ko05230	Central carbon metabolism in cancer	19/1084	81/7206	0.0411570495547
ko04217	Necroptosis	17/1084	178/7206	0.0428412739549
ko05215	Prostate cancer	9/1084	111/7206	0.0435094648749
ko05145	Toxoplasmosis	11/1084	126/7206	0.0442158385639
ko04960	Aldosterone-regulated sodium reabsorption	11/1084	41/7206	0.0459318044855
ko04213	Longevity regulating pathway - multiple species	20/1084	86/7206	0.0465367508832
ko00564	Glycerophospholipid metabolism	22/1084	99/7206	0.0480429697267
ko04115	p53 signaling pathway	5/1084	74/7206	0.0483494306924