ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	162/928	423/7206	5.51833964296e-43
ko04724	Glutamatergic synapse	80/928	152/7206	1.01275271967e-32
ko05033	Nicotine addiction	45/928	56/7206	1.23278576149e-30
ko04713	Circadian entrainment	68/928	136/7206	3.48529411335e-26
ko04727	GABAergic synapse	60/928	110/7206	7.57192480407e-26
ko05032	Morphine addiction	60/928	110/7206	7.57192480407e-26
ko04728	Dopaminergic synapse	78/928	185/7206	8.27340562243e-24
ko04725	Cholinergic synapse	68/928	160/7206	4.19611359131e-21
ko04723	Retrograde endocannabinoid signaling	70/928	175/7206	6.70837788457e-20
ko04721	Synaptic vesicle cycle	44/928	80/7206	1.93767629381e-19
ko04911	Insulin secretion	53/928	117/7206	3.52674659773e-18
ko04024	cAMP signaling pathway	87/928	279/7206	2.58794209959e-16
ko04726	Serotonergic synapse	54/928	137/7206	2.83110978642e-15
ko05031	Amphetamine addiction	41/928	91/7206	3.0700235506e-14
ko04742	Taste transduction	32/928	61/7206	1.05534347194e-13
ko04720	Long-term potentiation	42/928	99/7206	1.90316431787e-13
ko04921	Oxytocin signaling pathway	64/928	209/7206	7.00768583937e-12
ko04020	Calcium signaling pathway	75/928	265/7206	8.64608060082e-12
ko04970	Salivary secretion	38/928	95/7206	2.37758427935e-11
ko04261	Adrenergic signaling in cardiomyocytes	62/928	205/7206	3.76761708733e-11
ko04740	Olfactory transduction	32/928	80/7206	9.13337152222e-10
ko04925	Aldosterone synthesis and secretion	37/928	105/7206	3.00262362707e-09
ko04971	Gastric acid secretion	35/928	98/7206	5.36716271559e-09
ko05030	Cocaine addiction	29/928	73/7206	6.81419751234e-09
ko04010	MAPK signaling pathway	76/928	321/7206	5.283868337e-08
ko03040	Spliceosome	1/928	145/7206	5.79585524817e-08
ko04060	Cytokine-cytokine receptor interaction	4/928	191/7206	1.42312527732e-07
ko05168	Herpes simplex infection	4/928	182/7206	4.5411461302e-07
ko04744	Phototransduction	17/928	36/7206	4.98304434815e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/928	74/7206	7.25057083311e-07
ko04972	Pancreatic secretion	33/928	111/7206	2.15050656562e-06
ko04730	Long-term depression	26/928	78/7206	2.28780420702e-06
ko04514	Cell adhesion molecules (CAMs)	36/928	130/7206	7.18395156915e-06
ko04750	Inflammatory mediator regulation of TRP channels	34/928	122/7206	7.56418689682e-06
ko04621	NOD-like receptor signaling pathway	4/928	157/7206	9.46305996746e-06
ko04540	Gap junction	35/928	128/7206	1.16288416777e-05
ko05203	Viral carcinogenesis	14/928	277/7206	1.47530903599e-05
ko04915	Estrogen signaling pathway	35/928	131/7206	1.62883088982e-05
ko03013	RNA transport	5/928	166/7206	1.71002097097e-05
ko05322	Systemic lupus erythematosus	4/928	151/7206	2.01487633915e-05
ko04014	Ras signaling pathway	61/928	279/7206	2.24778723042e-05
ko04924	Renin secretion	26/928	86/7206	2.36149866587e-05
ko04360	Axon guidance	53/928	233/7206	2.37119755031e-05
ko04022	cGMP-PKG signaling pathway	50/928	216/7206	2.84494125122e-05
ko04745	Phototransduction - fly	15/928	38/7206	3.42930551386e-05
ko04072	Phospholipase D signaling pathway	45/928	197/7206	8.65714292768e-05
ko04120	Ubiquitin mediated proteolysis	4/928	138/7206	8.68457928809e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/928	59/7206	8.93647598767e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/928	79/7206	0.00011638443335
ko04070	Phosphatidylinositol signaling system	29/928	112/7206	0.000163064294169
ko04966	Collecting duct acid secretion	11/928	26/7206	0.000186112305712
ko04260	Cardiac muscle contraction	26/928	98/7206	0.000213897132568
ko04612	Antigen processing and presentation	1/928	77/7206	0.000477750048391
ko04973	Carbohydrate digestion and absorption	14/928	42/7206	0.000502153116295
ko03008	Ribosome biogenesis in eukaryotes	1/928	79/7206	0.000506577572665
ko04976	Bile secretion	22/928	80/7206	0.000540485703519
ko05164	Influenza A	8/928	167/7206	0.000639728224752
ko04214	Apoptosis - fly	1/928	72/7206	0.00109209948461
ko04141	Protein processing in endoplasmic reticulum	10/928	184/7206	0.00113488763674
ko04110	Cell cycle	7/928	145/7206	0.00164556464745
ko04015	Rap1 signaling pathway	54/928	278/7206	0.0017814768431
ko05110	Vibrio cholerae infection	17/928	63/7206	0.00213300907286
ko05162	Measles	5/928	120/7206	0.00220557748914
ko04912	GnRH signaling pathway	28/928	122/7206	0.00233507086851
ko04964	Proximal tubule bicarbonate reclamation	10/928	29/7206	0.00237291171143
ko05414	Dilated cardiomyopathy	26/928	112/7206	0.00244407600145
ko04930	Type II diabetes mellitus	15/928	54/7206	0.00318457952893
ko04916	Melanogenesis	31/928	142/7206	0.00322885751475
ko05231	Choline metabolism in cancer	29/928	134/7206	0.00394631078386
ko04350	TGF-beta signaling pathway	4/928	103/7206	0.00424794008268
ko04960	Aldosterone-regulated sodium reabsorption	12/928	41/7206	0.00429371635033
ko04371	Apelin signaling pathway	36/928	177/7206	0.00433130673615
ko04626	Plant-pathogen interaction	7/928	18/7206	0.00503573083178
ko04923	Regulation of lipolysis in adipocytes	19/928	77/7206	0.00517873752769
ko00240	Pyrimidine metabolism	5/928	110/7206	0.00587604418334
ko05169	Epstein-Barr virus infection	14/928	206/7206	0.0059279721761
ko05214	Glioma	19/928	79/7206	0.00600901178857
ko00480	Glutathione metabolism	1/928	55/7206	0.00772447769502
ko03018	RNA degradation	3/928	84/7206	0.00773519152199
ko04064	NF-kappa B signaling pathway	4/928	96/7206	0.00818212409548
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/928	182/7206	0.00943016091505
ko00590	Arachidonic acid metabolism	1/928	52/7206	0.0114486159436
ko04217	Necroptosis	12/928	178/7206	0.012134192687
ko04640	Hematopoietic cell lineage	2/928	64/7206	0.0138314202627
ko04918	Thyroid hormone synthesis	19/928	86/7206	0.0147202495453
ko05140	Leishmaniasis	3/928	75/7206	0.0149790865236
ko04657	IL-17 signaling pathway	4/928	87/7206	0.0152983081852
ko04146	Peroxisome	4/928	89/7206	0.0156161184571
ko04722	Neurotrophin signaling pathway	31/928	160/7206	0.016766403288
ko00260	Glycine, serine and threonine metabolism	1/928	48/7206	0.0168823092519
ko05034	Alcoholism	43/928	238/7206	0.0181029096273
ko04142	Lysosome	10/928	151/7206	0.0189750207619
ko00330	Arginine and proline metabolism	2/928	61/7206	0.019896659285
ko00310	Lysine degradation	3/928	73/7206	0.0211382710805
ko04062	Chemokine signaling pathway	37/928	201/7206	0.0242060810496
ko05144	Malaria	1/928	45/7206	0.0248717774486
ko00071	Fatty acid degradation	1/928	45/7206	0.0248717774486
ko03420	Nucleotide excision repair	1/928	46/7206	0.0250668455942
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/928	14/7206	0.0258019389072
ko05016	Huntington's disease	17/928	215/7206	0.029231483845
ko04012	ErbB signaling pathway	22/928	109/7206	0.0295096860823
ko04922	Glucagon signaling pathway	25/928	128/7206	0.0319588727178
ko04270	Vascular smooth muscle contraction	29/928	154/7206	0.0374998927561
ko05321	Inflammatory bowel disease (IBD)	2/928	56/7206	0.0418514484466
ko05205	Proteoglycans in cancer	24/928	271/7206	0.0420895152482
ko01200	Carbon metabolism	9/928	128/7206	0.0454822996909
ko05410	Hypertrophic cardiomyopathy (HCM)	20/928	100/7206	0.0485616867999