ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	32/411	56/7206	6.01092243145e-26
ko04724	Glutamatergic synapse	50/411	152/7206	8.37272429258e-26
ko04080	Neuroactive ligand-receptor interaction	73/411	423/7206	1.44317658298e-18
ko04728	Dopaminergic synapse	44/411	185/7206	1.07372081667e-16
ko04721	Synaptic vesicle cycle	28/411	80/7206	1.13164488958e-15
ko04727	GABAergic synapse	32/411	110/7206	4.24851666841e-15
ko04723	Retrograde endocannabinoid signaling	39/411	175/7206	6.53910895323e-14
ko04713	Circadian entrainment	33/411	136/7206	4.80442349718e-13
ko05032	Morphine addiction	29/411	110/7206	1.38450202959e-12
ko05030	Cocaine addiction	23/411	73/7206	5.41912559788e-12
ko05014	Amyotrophic lateral sclerosis (ALS)	21/411	74/7206	4.18257747756e-10
ko05031	Amphetamine addiction	22/411	91/7206	4.49706213128e-09
ko04911	Insulin secretion	24/411	117/7206	2.89077048504e-08
ko04514	Cell adhesion molecules (CAMs)	25/411	130/7206	5.74419090023e-08
ko04725	Cholinergic synapse	28/411	160/7206	7.64288646305e-08
ko04024	cAMP signaling pathway	39/411	279/7206	1.83291815022e-07
ko04720	Long-term potentiation	20/411	99/7206	5.46673818893e-07
ko04010	MAPK signaling pathway	41/411	321/7206	8.14197893464e-07
ko04261	Adrenergic signaling in cardiomyocytes	29/411	205/7206	4.42795360081e-06
ko05203	Viral carcinogenesis	2/411	277/7206	1.68156059686e-05
ko04020	Calcium signaling pathway	32/411	265/7206	5.99434818036e-05
ko04726	Serotonergic synapse	20/411	137/7206	8.81447858356e-05
ko04360	Axon guidance	28/411	233/7206	0.000146431884965
ko04921	Oxytocin signaling pathway	26/411	209/7206	0.000184751195194
ko04972	Pancreatic secretion	16/411	111/7206	0.000511596105305
ko04742	Taste transduction	11/411	61/7206	0.000570585674874
ko04260	Cardiac muscle contraction	14/411	98/7206	0.00123528185495
ko04970	Salivary secretion	13/411	95/7206	0.00270438813916
ko05205	Proteoglycans in cancer	5/411	271/7206	0.00294482291917
ko03040	Spliceosome	1/411	145/7206	0.00325450636525
ko04110	Cell cycle	1/411	145/7206	0.00325450636525
ko04915	Estrogen signaling pathway	16/411	131/7206	0.0034735501853
ko05169	Epstein-Barr virus infection	3/411	206/7206	0.00350183023086
ko04730	Long-term depression	11/411	78/7206	0.00444344392583
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	11/411	79/7206	0.00490556205176
ko04140	Autophagy - animal	2/411	164/7206	0.00606014011609
ko05164	Influenza A	2/411	167/7206	0.00611502970565
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/411	14/7206	0.00660509894342
ko04630	Jak-STAT signaling pathway	1/411	132/7206	0.00694497528164
ko04621	NOD-like receptor signaling pathway	2/411	157/7206	0.00860748133887
ko04510	Focal adhesion	5/411	240/7206	0.0101346852566
ko01200	Carbon metabolism	1/411	128/7206	0.0105060063223
ko05414	Dilated cardiomyopathy	13/411	112/7206	0.0122938684263
ko05168	Herpes simplex infection	3/411	182/7206	0.0137296529688
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/411	182/7206	0.0137296529688
ko05034	Alcoholism	23/411	238/7206	0.0144416799035
ko04961	Endocrine and other factor-regulated calcium reabsorption	8/411	59/7206	0.0179794842061
ko00240	Pyrimidine metabolism	1/411	110/7206	0.0210336815383
ko05215	Prostate cancer	1/411	111/7206	0.0211736881932
ko04931	Insulin resistance	2/411	137/7206	0.0243287433261
ko04120	Ubiquitin mediated proteolysis	2/411	138/7206	0.0244451002398
ko03013	RNA transport	3/411	166/7206	0.0258965683846
ko05410	Hypertrophic cardiomyopathy (HCM)	11/411	100/7206	0.02922184906
ko05010	Alzheimer's disease	19/411	202/7206	0.0297106938647
ko04150	mTOR signaling pathway	4/411	184/7206	0.0347740987726
ko04141	Protein processing in endoplasmic reticulum	4/411	184/7206	0.0347740987726
ko04022	cGMP-PKG signaling pathway	20/411	216/7206	0.0349516912206
ko04072	Phospholipase D signaling pathway	18/411	197/7206	0.0420802023671
ko04064	NF-kappa B signaling pathway	1/411	96/7206	0.0438049151376
ko04015	Rap1 signaling pathway	24/411	278/7206	0.0461408522834
ko04218	Cellular senescence	4/411	177/7206	0.0469908377973
ko04217	Necroptosis	4/411	178/7206	0.0472783413336