ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	127/660	423/7206	4.92797386516e-37
ko04724	Glutamatergic synapse	73/660	152/7206	1.4932915108e-36
ko05033	Nicotine addiction	42/660	56/7206	1.2564626007e-32
ko04713	Circadian entrainment	60/660	136/7206	1.33915735537e-27
ko04728	Dopaminergic synapse	69/660	185/7206	2.75670594862e-26
ko05032	Morphine addiction	49/660	110/7206	6.27666722949e-23
ko04727	GABAergic synapse	48/660	110/7206	5.2828894607e-22
ko04723	Retrograde endocannabinoid signaling	60/660	175/7206	8.86670989597e-21
ko05031	Amphetamine addiction	38/660	91/7206	7.33581369467e-17
ko04911	Insulin secretion	43/660	117/7206	1.86095117672e-16
ko04725	Cholinergic synapse	51/660	160/7206	2.77946872247e-16
ko04720	Long-term potentiation	39/660	99/7206	3.12360101329e-16
ko04024	cAMP signaling pathway	70/660	279/7206	1.01667922819e-15
ko04020	Calcium signaling pathway	67/660	265/7206	2.91932102619e-15
ko04721	Synaptic vesicle cycle	33/660	80/7206	1.29204966974e-14
ko04726	Serotonergic synapse	42/660	137/7206	5.80135811523e-13
ko04261	Adrenergic signaling in cardiomyocytes	51/660	205/7206	1.40915937257e-11
ko04921	Oxytocin signaling pathway	51/660	209/7206	3.0571315647e-11
ko04970	Salivary secretion	31/660	95/7206	1.15046811453e-10
ko05014	Amyotrophic lateral sclerosis (ALS)	25/660	74/7206	3.30556361714e-09
ko04925	Aldosterone synthesis and secretion	30/660	105/7206	8.17382995007e-09
ko05030	Cocaine addiction	24/660	73/7206	1.26390085379e-08
ko04010	MAPK signaling pathway	59/660	321/7206	1.47761785579e-07
ko04742	Taste transduction	20/660	61/7206	2.19937425216e-07
ko04022	cGMP-PKG signaling pathway	44/660	216/7206	2.57249702268e-07
ko04060	Cytokine-cytokine receptor interaction	1/660	191/7206	3.14180079199e-07
ko04740	Olfactory transduction	23/660	80/7206	4.06178012474e-07
ko04971	Gastric acid secretion	26/660	98/7206	4.12925681112e-07
ko04972	Pancreatic secretion	28/660	111/7206	4.63164763399e-07
ko04745	Phototransduction - fly	15/660	38/7206	4.7776533921e-07
ko04070	Phosphatidylinositol signaling system	27/660	112/7206	1.93643797057e-06
ko04730	Long-term depression	21/660	78/7206	4.16508226617e-06
ko04924	Renin secretion	21/660	86/7206	2.16458225399e-05
ko04072	Phospholipase D signaling pathway	37/660	197/7206	2.34073931586e-05
ko03040	Spliceosome	1/660	145/7206	2.70714678557e-05
ko05168	Herpes simplex infection	3/660	182/7206	4.20216638919e-05
ko04744	Phototransduction	12/660	36/7206	5.01421078968e-05
ko05203	Viral carcinogenesis	9/660	277/7206	0.000168831202148
ko04014	Ras signaling pathway	45/660	279/7206	0.000175617710877
ko05164	Influenza A	3/660	167/7206	0.000186157913221
ko04260	Cardiac muscle contraction	21/660	98/7206	0.000242979279643
ko04915	Estrogen signaling pathway	25/660	131/7206	0.00033398948274
ko04912	GnRH signaling pathway	24/660	122/7206	0.00033620273727
ko04626	Plant-pathogen interaction	7/660	18/7206	0.00067724558317
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/660	59/7206	0.000687912917456
ko04750	Inflammatory mediator regulation of TRP channels	23/660	122/7206	0.000699254500719
ko04973	Carbohydrate digestion and absorption	11/660	42/7206	0.00106542330842
ko05034	Alcoholism	37/660	238/7206	0.0012363157321
ko04966	Collecting duct acid secretion	8/660	26/7206	0.00166612350894
ko04621	NOD-like receptor signaling pathway	4/660	157/7206	0.00178737884885
ko04514	Cell adhesion molecules (CAMs)	23/660	130/7206	0.00182730657236
ko05169	Epstein-Barr virus infection	7/660	206/7206	0.00197188133241
ko04371	Apelin signaling pathway	29/660	177/7206	0.00208152808612
ko05214	Glioma	16/660	79/7206	0.00231372024773
ko05322	Systemic lupus erythematosus	4/660	151/7206	0.00245582904005
ko03013	RNA transport	5/660	166/7206	0.00259709388499
ko00562	Inositol phosphate metabolism	17/660	89/7206	0.00277217465065
ko04110	Cell cycle	4/660	145/7206	0.00341406718757
ko04964	Proximal tubule bicarbonate reclamation	8/660	29/7206	0.00357845829447
ko05010	Alzheimer's disease	31/660	202/7206	0.00404820793009
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/660	79/7206	0.00527904984806
ko04350	TGF-beta signaling pathway	2/660	103/7206	0.00538950058465
ko05231	Choline metabolism in cancer	22/660	134/7206	0.00604010842856
ko05162	Measles	3/660	120/7206	0.00617102103532
ko04120	Ubiquitin mediated proteolysis	4/660	138/7206	0.00665451183936
ko04540	Gap junction	21/660	128/7206	0.00778350545785
ko04141	Protein processing in endoplasmic reticulum	7/660	184/7206	0.00892178633813
ko03008	Ribosome biogenesis in eukaryotes	1/660	79/7206	0.00918559436679
ko04960	Aldosterone-regulated sodium reabsorption	9/660	41/7206	0.0103928070033
ko04114	Oocyte meiosis	22/660	139/7206	0.0106244677026
ko04360	Axon guidance	33/660	233/7206	0.0106442559373
ko04015	Rap1 signaling pathway	38/660	278/7206	0.0107147603052
ko00240	Pyrimidine metabolism	3/660	110/7206	0.0121223898968
ko04214	Apoptosis - fly	1/660	72/7206	0.0130544918819
ko05110	Vibrio cholerae infection	12/660	63/7206	0.0130764441228
ko00512	Mucin type O-glycan biosynthesis	7/660	29/7206	0.013665935062
ko04930	Type II diabetes mellitus	11/660	54/7206	0.0141600127841
ko04722	Neurotrophin signaling pathway	24/660	160/7206	0.0172326132599
ko04922	Glucagon signaling pathway	20/660	128/7206	0.0187644849451
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/660	182/7206	0.0256690501545
ko04978	Mineral absorption	8/660	40/7206	0.0262409227798
ko04550	Signaling pathways regulating pluripotency of stem cells	7/660	165/7206	0.0275867750929
ko00600	Sphingolipid metabolism	1/660	63/7206	0.027760674721
ko04012	ErbB signaling pathway	17/660	109/7206	0.0277873025215
ko05152	Tuberculosis	26/660	187/7206	0.0284142888992
ko04630	Jak-STAT signaling pathway	5/660	132/7206	0.0313459404572
ko04064	NF-kappa B signaling pathway	3/660	96/7206	0.0325834495711
ko04270	Vascular smooth muscle contraction	22/660	154/7206	0.0331489247959
ko04918	Thyroid hormone synthesis	14/660	86/7206	0.0352717841279
ko04510	Focal adhesion	13/660	240/7206	0.0400640476211
ko00330	Arginine and proline metabolism	1/660	61/7206	0.04120221385
ko04330	Notch signaling pathway	1/660	62/7206	0.0421279784358
ko04612	Antigen processing and presentation	2/660	77/7206	0.0447168151785
ko04976	Bile secretion	13/660	80/7206	0.0473031984436