ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	137/726	423/7206	2.58650726343e-39
ko04724	Glutamatergic synapse	77/726	152/7206	1.23265574536e-37
ko05033	Nicotine addiction	42/726	56/7206	6.78036028259e-31
ko04727	GABAergic synapse	53/726	110/7206	9.26575506143e-25
ko05032	Morphine addiction	53/726	110/7206	9.26575506143e-25
ko04713	Circadian entrainment	56/726	136/7206	6.5444811544e-22
ko04728	Dopaminergic synapse	66/726	185/7206	1.52900736462e-21
ko04723	Retrograde endocannabinoid signaling	63/726	175/7206	7.70351074206e-21
ko04020	Calcium signaling pathway	72/726	265/7206	6.75222371315e-16
ko04725	Cholinergic synapse	53/726	160/7206	6.87457589952e-16
ko05030	Cocaine addiction	34/726	73/7206	1.01247415141e-15
ko04911	Insulin secretion	43/726	117/7206	6.14047741924e-15
ko05031	Amphetamine addiction	37/726	91/7206	1.19131867131e-14
ko04921	Oxytocin signaling pathway	60/726	209/7206	1.38370527548e-14
ko04024	cAMP signaling pathway	71/726	279/7206	4.26268342527e-14
ko04720	Long-term potentiation	36/726	99/7206	1.51204508181e-12
ko04261	Adrenergic signaling in cardiomyocytes	54/726	205/7206	1.32893910842e-11
ko04742	Taste transduction	26/726	61/7206	3.12509213666e-11
ko04726	Serotonergic synapse	41/726	137/7206	5.79993625162e-11
ko04010	MAPK signaling pathway	71/726	321/7206	6.6848604785e-11
ko04925	Aldosterone synthesis and secretion	33/726	105/7206	1.10691926403e-09
ko04970	Salivary secretion	30/726	95/7206	5.63119442233e-09
ko04730	Long-term depression	26/726	78/7206	1.6758454648e-08
ko04721	Synaptic vesicle cycle	26/726	80/7206	3.03980413864e-08
ko04540	Gap junction	32/726	128/7206	7.79866186565e-07
ko04072	Phospholipase D signaling pathway	43/726	197/7206	7.94150531184e-07
ko04971	Gastric acid secretion	26/726	98/7206	2.57420697696e-06
ko04972	Pancreatic secretion	28/726	111/7206	3.15777868893e-06
ko04060	Cytokine-cytokine receptor interaction	3/726	191/7206	4.15164131556e-06
ko04022	cGMP-PKG signaling pathway	44/726	216/7206	4.75571579481e-06
ko04915	Estrogen signaling pathway	31/726	131/7206	4.85468250509e-06
ko05203	Viral carcinogenesis	8/726	277/7206	5.64675683147e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	21/726	74/7206	7.55049901462e-06
ko05414	Dilated cardiomyopathy	27/726	112/7206	1.79528018401e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/726	79/7206	2.28065517288e-05
ko04070	Phosphatidylinositol signaling system	26/726	112/7206	4.07238004551e-05
ko04924	Renin secretion	21/726	86/7206	8.9033578756e-05
ko04750	Inflammatory mediator regulation of TRP channels	26/726	122/7206	0.000189921376021
ko05168	Herpes simplex infection	5/726	182/7206	0.000243844440881
ko04740	Olfactory transduction	19/726	80/7206	0.00028108456052
ko04110	Cell cycle	3/726	145/7206	0.00037601672731
ko00515	Mannose type O-glycan biosynthesis	9/726	25/7206	0.000469978976059
ko04514	Cell adhesion molecules (CAMs)	26/726	130/7206	0.000568321869068
ko04912	GnRH signaling pathway	25/726	122/7206	0.000632166765208
ko05322	Systemic lupus erythematosus	4/726	151/7206	0.000864787582768
ko03013	RNA transport	5/726	166/7206	0.000945947825665
ko00240	Pyrimidine metabolism	2/726	110/7206	0.0011999891423
ko04360	Axon guidance	39/726	233/7206	0.00124562616861
ko04923	Regulation of lipolysis in adipocytes	17/726	77/7206	0.00166547496468
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/726	59/7206	0.00175118946254
ko05034	Alcoholism	39/726	238/7206	0.00201085111378
ko04930	Type II diabetes mellitus	13/726	54/7206	0.0022018573208
ko04142	Lysosome	5/726	151/7206	0.00249784117972
ko00562	Inositol phosphate metabolism	18/726	89/7206	0.00372352891172
ko03008	Ribosome biogenesis in eukaryotes	1/726	79/7206	0.00403606066578
ko05205	Proteoglycans in cancer	14/726	271/7206	0.00516476444519
ko04260	Cardiac muscle contraction	19/726	98/7206	0.00576880314308
ko04918	Thyroid hormone synthesis	17/726	86/7206	0.00589222170656
ko04141	Protein processing in endoplasmic reticulum	8/726	184/7206	0.00604885883362
ko05410	Hypertrophic cardiomyopathy (HCM)	19/726	100/7206	0.00639996303856
ko00190	Oxidative phosphorylation	4/726	127/7206	0.00660777762852
ko04146	Peroxisome	2/726	89/7206	0.00745164598409
ko04371	Apelin signaling pathway	29/726	177/7206	0.00756638432763
ko04071	Sphingolipid signaling pathway	27/726	162/7206	0.00784760928376
ko04744	Phototransduction	9/726	36/7206	0.00789077145033
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/726	182/7206	0.00821116563916
ko04270	Vascular smooth muscle contraction	26/726	154/7206	0.00929342467068
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/726	14/7206	0.00945013865616
ko04916	Melanogenesis	24/726	142/7206	0.0105204741786
ko04015	Rap1 signaling pathway	41/726	278/7206	0.0109262355427
ko04745	Phototransduction - fly	9/726	38/7206	0.0113903813754
ko04145	Phagosome	7/726	162/7206	0.0114309976104
ko04350	TGF-beta signaling pathway	3/726	103/7206	0.0120758702591
ko05231	Choline metabolism in cancer	23/726	134/7206	0.0126625228409
ko04962	Vasopressin-regulated water reabsorption	12/726	58/7206	0.0135789974586
ko03018	RNA degradation	2/726	84/7206	0.0158174363117
ko00512	Mucin type O-glycan biosynthesis	7/726	29/7206	0.0221901325417
ko04530	Tight junction	13/726	228/7206	0.0247418117629
ko05202	Transcriptional misregulation in cancer	10/726	188/7206	0.0264589263177
ko04144	Endocytosis	47/726	342/7206	0.0266769450773
ko01212	Fatty acid metabolism	1/726	60/7206	0.0279553453952
ko04630	Jak-STAT signaling pathway	6/726	132/7206	0.0284297093291
ko05162	Measles	5/726	120/7206	0.030637058526
ko00513	Various types of N-glycan biosynthesis	9/726	42/7206	0.0330961395492
ko00520	Amino sugar and nucleotide sugar metabolism	1/726	55/7206	0.0399339376068
ko00480	Glutathione metabolism	1/726	55/7206	0.0399339376068
ko05321	Inflammatory bowel disease (IBD)	1/726	56/7206	0.0407742368476
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	6/726	26/7206	0.040835516783
ko04062	Chemokine signaling pathway	29/726	201/7206	0.042996235672
ko03320	PPAR signaling pathway	2/726	69/7206	0.0434408599857
ko05169	Epstein-Barr virus infection	12/726	206/7206	0.0447170067293
ko00430	Taurine and hypotaurine metabolism	4/726	14/7206	0.0450203517195
ko04120	Ubiquitin mediated proteolysis	7/726	138/7206	0.0456509667959
ko05164	Influenza A	9/726	167/7206	0.0494577538411