ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 42/281 145/7206 5.54957270601e-26 ko04110 Cell cycle 34/281 145/7206 5.80465550729e-18 ko04111 Cell cycle - yeast 24/281 90/7206 2.51720743297e-14 ko03440 Homologous recombination 13/281 41/7206 2.4193252832e-09 ko04113 Meiosis - yeast 16/281 70/7206 6.93479841153e-09 ko03013 RNA transport 24/281 166/7206 2.12204684931e-08 ko03022 Basal transcription factors 12/281 44/7206 6.75095182472e-08 ko03460 Fanconi anemia pathway 12/281 51/7206 3.97746155248e-07 ko04080 Neuroactive ligand-receptor interaction 1/281 423/7206 8.95907965107e-07 ko03018 RNA degradation 14/281 84/7206 3.6985687832e-06 ko03410 Base excision repair 9/281 38/7206 1.10404885077e-05 ko03030 DNA replication 9/281 38/7206 1.10404885077e-05 ko04114 Oocyte meiosis 17/281 139/7206 2.55913357553e-05 ko03420 Nucleotide excision repair 9/281 46/7206 5.67098552202e-05 ko05322 Systemic lupus erythematosus 17/281 151/7206 7.45420142138e-05 ko05203 Viral carcinogenesis 25/281 277/7206 8.43862289755e-05 ko04144 Endocytosis 2/281 342/7206 0.000251940183863 ko04020 Calcium signaling pathway 1/281 265/7206 0.000512562149273 ko03020 RNA polymerase 6/281 29/7206 0.000741598593738 ko03015 mRNA surveillance pathway 11/281 93/7206 0.000922775979563 ko03430 Mismatch repair 5/281 22/7206 0.00132633550426 ko04115 p53 signaling pathway 9/281 74/7206 0.00219012128434 ko04024 cAMP signaling pathway 2/281 279/7206 0.00223558708522 ko04914 Progesterone-mediated oocyte maturation 11/281 104/7206 0.00231200128769 ko04151 PI3K-Akt signaling pathway 5/281 390/7206 0.00291156603248 ko04810 Regulation of actin cytoskeleton 2/281 264/7206 0.0030941292786 ko03008 Ribosome biogenesis in eukaryotes 9/281 79/7206 0.00344283290091 ko04022 cGMP-PKG signaling pathway 1/281 216/7206 0.00349261150214 ko00240 Pyrimidine metabolism 11/281 110/7206 0.00359651513613 ko04510 Focal adhesion 2/281 240/7206 0.00626057902762 ko04014 Ras signaling pathway 3/281 279/7206 0.00705338274881 ko04060 Cytokine-cytokine receptor interaction 1/281 191/7206 0.00717522815912 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/281 191/7206 0.00717522815912 ko04072 Phospholipase D signaling pathway 1/281 197/7206 0.00749798216089 ko04360 Axon guidance 2/281 233/7206 0.0089374193117 ko05205 Proteoglycans in cancer 3/281 271/7206 0.00983998484657 ko04015 Rap1 signaling pathway 3/281 278/7206 0.0102232305884 ko05200 Pathways in cancer 9/281 492/7206 0.0108655138243 ko05224 Breast cancer 1/281 174/7206 0.0153288496255 ko04371 Apelin signaling pathway 1/281 177/7206 0.0157977849383 ko04071 Sphingolipid signaling pathway 1/281 162/7206 0.0218880254204 ko04611 Platelet activation 1/281 163/7206 0.0220155288773 ko05164 Influenza A 1/281 167/7206 0.0228598452874 ko04010 MAPK signaling pathway 5/281 321/7206 0.0254384832201 ko05012 Parkinson's disease 1/281 155/7206 0.0322981135742 ko04931 Insulin resistance 1/281 137/7206 0.0449538734952 ko04726 Serotonergic synapse 1/281 137/7206 0.0449538734952 ko04916 Melanogenesis 1/281 142/7206 0.0454679231274 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/281 182/7206 0.0495192431385