ko pathway ratio_in_study ratio_in_pop p_value ko05032 Morphine addiction 10/116 110/7206 9.6068068654e-06 ko04911 Insulin secretion 10/116 117/7206 1.66261365197e-05 ko04912 GnRH signaling pathway 10/116 122/7206 2.40155592321e-05 ko04724 Glutamatergic synapse 11/116 152/7206 3.00257032481e-05 ko04925 Aldosterone synthesis and secretion 9/116 105/7206 4.38189701004e-05 ko04010 MAPK signaling pathway 16/116 321/7206 4.97916177481e-05 ko04713 Circadian entrainment 10/116 136/7206 6.13329393664e-05 ko04727 GABAergic synapse 9/116 110/7206 6.33100172056e-05 ko04072 Phospholipase D signaling pathway 12/116 197/7206 7.09892896286e-05 ko04070 Phosphatidylinositol signaling system 9/116 112/7206 7.29307905163e-05 ko04211 Longevity regulating pathway 8/116 123/7206 0.000782056999259 ko04540 Gap junction 8/116 128/7206 0.00101577262126 ko04725 Cholinergic synapse 9/116 160/7206 0.0010501525035 ko05030 Cocaine addiction 6/116 73/7206 0.00108171828501 ko04915 Estrogen signaling pathway 8/116 131/7206 0.00118090748133 ko05231 Choline metabolism in cancer 8/116 134/7206 0.00136683201324 ko04914 Progesterone-mediated oocyte maturation 7/116 104/7206 0.00137043943212 ko04923 Regulation of lipolysis in adipocytes 6/116 77/7206 0.00143017835726 ko04723 Retrograde endocannabinoid signaling 9/116 175/7206 0.00196345238416 ko04213 Longevity regulating pathway - multiple species 6/116 86/7206 0.00252301719176 ko04918 Thyroid hormone synthesis 6/116 86/7206 0.00252301719176 ko00562 Inositol phosphate metabolism 6/116 89/7206 0.00299935829942 ko04270 Vascular smooth muscle contraction 8/116 154/7206 0.00328009582242 ko04913 Ovarian steroidogenesis 5/116 63/7206 0.00331350306881 ko05031 Amphetamine addiction 6/116 91/7206 0.0033523510035 ko04970 Salivary secretion 6/116 95/7206 0.00415019439143 ko04062 Chemokine signaling pathway 9/116 201/7206 0.00496069282602 ko00564 Glycerophospholipid metabolism 6/116 99/7206 0.00508074081575 ko04261 Adrenergic signaling in cardiomyocytes 9/116 205/7206 0.00563578346275 ko00515 Mannose type O-glycan biosynthesis 3/116 25/7206 0.00722168491397 ko04022 cGMP-PKG signaling pathway 9/116 216/7206 0.00786281134148 ko04972 Pancreatic secretion 6/116 111/7206 0.0087920390088 ko04976 Bile secretion 5/116 80/7206 0.00913580937607 ko05414 Dilated cardiomyopathy 6/116 112/7206 0.00917064182527 ko04020 Calcium signaling pathway 10/116 265/7206 0.0101046981671 ko04144 Endocytosis 12/116 342/7206 0.0120803997036 ko04668 TNF signaling pathway 6/116 120/7206 0.012630524175 ko04750 Inflammatory mediator regulation of TRP channels 6/116 122/7206 0.013621823998 ko04024 cAMP signaling pathway 10/116 279/7206 0.0141444734502 ko01522 Endocrine resistance 6/116 124/7206 0.0146664456312 ko04611 Platelet activation 7/116 163/7206 0.0158439536441 ko00561 Glycerolipid metabolism 4/116 63/7206 0.0183269701167 ko04971 Gastric acid secretion 5/116 98/7206 0.0205719851534 ko04720 Long-term potentiation 5/116 99/7206 0.0213959875119 ko04371 Apelin signaling pathway 7/116 177/7206 0.0237557179332 ko04114 Oocyte meiosis 6/116 139/7206 0.0243303622062 ko04728 Dopaminergic synapse 7/116 185/7206 0.0293313262314 ko00230 Purine metabolism 7/116 194/7206 0.0365963134991 ko04138 Autophagy - yeast 4/116 81/7206 0.0411553318946 ko00510 N-Glycan biosynthesis 3/116 50/7206 0.0461164420414 ko04924 Renin secretion 4/116 86/7206 0.0494601145165