ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 9/111 120/7206 8.85824233611e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/111 191/7206 0.000159611593407 ko04621 NOD-like receptor signaling pathway 9/111 157/7206 0.000667271604668 ko04215 Apoptosis - multiple species 5/111 47/7206 0.000725970331606 ko04380 Osteoclast differentiation 8/111 134/7206 0.00102649844295 ko05164 Influenza A 9/111 167/7206 0.00103837283174 ko05131 Shigellosis 6/111 82/7206 0.00157987794609 ko04670 Leukocyte transendothelial migration 8/111 151/7206 0.00220431571159 ko04060 Cytokine-cytokine receptor interaction 9/111 191/7206 0.00263244054975 ko04660 T cell receptor signaling pathway 7/111 124/7206 0.00291736517985 ko04725 Cholinergic synapse 8/111 160/7206 0.00315927843076 ko04062 Chemokine signaling pathway 9/111 201/7206 0.00370401730306 ko05100 Bacterial invasion of epithelial cells 6/111 99/7206 0.00409539020771 ko04932 Non-alcoholic fatty liver disease (NAFLD) 8/111 182/7206 0.00685266507291 ko04966 Collecting duct acid secretion 3/111 26/7206 0.00714627474985 ko05160 Hepatitis C 7/111 153/7206 0.00913298071925 ko04722 Neurotrophin signaling pathway 7/111 160/7206 0.0115175190478 ko04211 Longevity regulating pathway 6/111 123/7206 0.0115519298705 ko05323 Rheumatoid arthritis 5/111 89/7206 0.0118021061126 ko05120 Epithelial cell signaling in Helicobacter pylori infection 5/111 92/7206 0.0134866728344 ko05166 HTLV-I infection 10/111 292/7206 0.0142268454581 ko04064 NF-kappa B signaling pathway 5/111 96/7206 0.0159756956252 ko04650 Natural killer cell mediated cytotoxicity 5/111 97/7206 0.0166427381603 ko05161 Hepatitis B 7/111 173/7206 0.0170970928409 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/111 135/7206 0.0176232979961 ko04620 Toll-like receptor signaling pathway 5/111 100/7206 0.0187545280073 ko04931 Insulin resistance 6/111 137/7206 0.0188142694709 ko04217 Necroptosis 7/111 178/7206 0.0196816291289 ko04210 Apoptosis 7/111 180/7206 0.0207883962967 ko04080 Neuroactive ligand-receptor interaction 1/111 423/7206 0.0220264729845 ko00051 Fructose and mannose metabolism 3/111 42/7206 0.026430795376 ko05215 Prostate cancer 5/111 111/7206 0.0279853894771 ko01524 Platinum drug resistance 4/111 76/7206 0.0293186371258 ko04721 Synaptic vesicle cycle 4/111 80/7206 0.0345087474115 ko05230 Central carbon metabolism in cancer 4/111 81/7206 0.0358846119219 ko00120 Primary bile acid biosynthesis 2/111 20/7206 0.0372984842054 ko05162 Measles 5/111 120/7206 0.0373762359768 ko04152 AMPK signaling pathway 6/111 161/7206 0.0375934859662 ko04145 Phagosome 6/111 162/7206 0.0385672779775 ko05212 Pancreatic cancer 4/111 83/7206 0.0387307655825 ko05203 Viral carcinogenesis 9/111 277/7206 0.0390815529466 ko04666 Fc gamma R-mediated phagocytosis 5/111 122/7206 0.0396967166643 ko05220 Chronic myeloid leukemia 4/111 85/7206 0.0417030344808 ko04213 Longevity regulating pathway - multiple species 4/111 86/7206 0.0432364980761 ko04068 FoxO signaling pathway 6/111 167/7206 0.0436780198117 ko05145 Toxoplasmosis 5/111 126/7206 0.0445970696383 ko04662 B cell receptor signaling pathway 4/111 88/7206 0.0463980528485 ko05222 Small cell lung cancer 4/111 89/7206 0.0480260974008 ko05142 Chagas disease (American trypanosomiasis) 5/111 130/7206 0.0498459211667