ko pathway ratio_in_study ratio_in_pop p_value ko05033 Nicotine addiction 12/246 56/7206 2.81672533747e-07 ko04724 Glutamatergic synapse 19/246 152/7206 8.46467561556e-07 ko04024 cAMP signaling pathway 26/246 279/7206 2.63894838738e-06 ko04360 Axon guidance 23/246 233/7206 3.91995501992e-06 ko04728 Dopaminergic synapse 19/246 185/7206 1.60045467556e-05 ko05032 Morphine addiction 14/246 110/7206 1.98831422549e-05 ko04723 Retrograde endocannabinoid signaling 18/246 175/7206 2.63635613189e-05 ko00604 Glycosphingolipid biosynthesis - ganglio series 5/246 14/7206 6.92258644249e-05 ko04727 GABAergic synapse 12/246 110/7206 0.00034565780761 ko04514 Cell adhesion molecules (CAMs) 13/246 130/7206 0.000465486853771 ko04713 Circadian entrainment 13/246 136/7206 0.0007179422401 ko04010 MAPK signaling pathway 23/246 321/7206 0.00071821912555 ko00515 Mannose type O-glycan biosynthesis 5/246 25/7206 0.00135030034472 ko04144 Endocytosis 22/246 342/7206 0.00350371778973 ko04261 Adrenergic signaling in cardiomyocytes 15/246 205/7206 0.00500530435032 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8/246 79/7206 0.00530000621527 ko04721 Synaptic vesicle cycle 8/246 80/7206 0.00571994645329 ko04911 Insulin secretion 10/246 117/7206 0.00648677988493 ko00510 N-Glycan biosynthesis 6/246 50/7206 0.00672191175851 ko04080 Neuroactive ligand-receptor interaction 25/246 423/7206 0.00790127236336 ko04930 Type II diabetes mellitus 6/246 54/7206 0.00975933278464 ko05030 Cocaine addiction 7/246 73/7206 0.011889285685 ko05031 Amphetamine addiction 8/246 91/7206 0.0121858470594 ko04071 Sphingolipid signaling pathway 12/246 162/7206 0.0126364515015 ko00513 Various types of N-glycan biosynthesis 5/246 42/7206 0.0135089023995 ko04973 Carbohydrate digestion and absorption 5/246 42/7206 0.0135089023995 ko04260 Cardiac muscle contraction 8/246 98/7206 0.0184310471185 ko05206 MicroRNAs in cancer 12/246 177/7206 0.0197526555582 ko04915 Estrogen signaling pathway 9/246 131/7206 0.0449538306486 ko03013 RNA transport 1/246 166/7206 0.046895569163