ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	142/843	423/7206	5.4427782579e-35
ko04724	Glutamatergic synapse	75/843	152/7206	3.89197502382e-31
ko05033	Nicotine addiction	43/843	56/7206	1.36351937955e-29
ko05032	Morphine addiction	59/843	110/7206	3.58093455229e-27
ko04727	GABAergic synapse	56/843	110/7206	2.46379764019e-24
ko04723	Retrograde endocannabinoid signaling	68/843	175/7206	6.93541694782e-21
ko04713	Circadian entrainment	58/843	136/7206	2.70753854371e-20
ko04024	cAMP signaling pathway	86/843	279/7206	1.8442758579e-18
ko04728	Dopaminergic synapse	64/843	185/7206	1.02397080766e-16
ko04725	Cholinergic synapse	57/843	160/7206	1.16794750724e-15
ko04726	Serotonergic synapse	48/843	137/7206	4.64013767207e-13
ko04911	Insulin secretion	43/843	117/7206	1.21820992836e-12
ko04921	Oxytocin signaling pathway	60/843	209/7206	1.40188606603e-11
ko04020	Calcium signaling pathway	70/843	265/7206	1.6041797211e-11
ko04261	Adrenergic signaling in cardiomyocytes	58/843	205/7206	5.12888751782e-11
ko04721	Synaptic vesicle cycle	32/843	80/7206	7.43406203481e-11
ko04742	Taste transduction	25/843	61/7206	4.99240815374e-09
ko04010	MAPK signaling pathway	73/843	321/7206	1.16421209865e-08
ko04970	Salivary secretion	30/843	95/7206	1.74370960383e-07
ko05031	Amphetamine addiction	29/843	91/7206	2.24601735661e-07
ko04022	cGMP-PKG signaling pathway	52/843	216/7206	2.34777263232e-07
ko05030	Cocaine addiction	25/843	73/7206	3.29260350384e-07
ko04072	Phospholipase D signaling pathway	48/843	197/7206	4.35015956525e-07
ko04720	Long-term potentiation	30/843	99/7206	4.77722792157e-07
ko04514	Cell adhesion molecules (CAMs)	36/843	130/7206	5.02883542313e-07
ko03040	Spliceosome	1/843	145/7206	5.70417318247e-07
ko05203	Viral carcinogenesis	10/843	277/7206	2.153650075e-06
ko04972	Pancreatic secretion	30/843	111/7206	7.54047165162e-06
ko04925	Aldosterone synthesis and secretion	29/843	105/7206	7.85232460146e-06
ko04730	Long-term depression	23/843	78/7206	1.70215289165e-05
ko04260	Cardiac muscle contraction	26/843	98/7206	4.31407674041e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/843	79/7206	6.81052318678e-05
ko04360	Axon guidance	48/843	233/7206	6.87820588284e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/843	74/7206	7.34090742028e-05
ko03013	RNA transport	5/843	166/7206	7.69726468859e-05
ko04915	Estrogen signaling pathway	31/843	131/7206	9.26257189765e-05
ko05322	Systemic lupus erythematosus	4/843	151/7206	9.34435501821e-05
ko04744	Phototransduction	13/843	36/7206	0.000122759914316
ko04971	Gastric acid secretion	25/843	98/7206	0.000174140099445
ko00240	Pyrimidine metabolism	2/843	110/7206	0.000245498062952
ko04070	Phosphatidylinositol signaling system	27/843	112/7206	0.00026601894722
ko04060	Cytokine-cytokine receptor interaction	8/843	191/7206	0.000364671338466
ko04540	Gap junction	29/843	128/7206	0.000406021547737
ko05414	Dilated cardiomyopathy	26/843	112/7206	0.000509835343909
ko04110	Cell cycle	5/843	145/7206	0.000609295827317
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/843	59/7206	0.000898917971706
ko04930	Type II diabetes mellitus	15/843	54/7206	0.000984710573837
ko04014	Ras signaling pathway	51/843	279/7206	0.00113550689097
ko04610	Complement and coagulation cascades	1/843	79/7206	0.00116467947624
ko03008	Ribosome biogenesis in eukaryotes	1/843	79/7206	0.00116467947624
ko04711	Circadian rhythm - fly	6/843	13/7206	0.00208769828962
ko05231	Choline metabolism in cancer	28/843	134/7206	0.00245562789854
ko05169	Epstein-Barr virus infection	11/843	206/7206	0.00275063397454
ko05164	Influenza A	8/843	167/7206	0.00317886089621
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/843	14/7206	0.0032953766112
ko05205	Proteoglycans in cancer	17/843	271/7206	0.00364187362665
ko04964	Proximal tubule bicarbonate reclamation	9/843	29/7206	0.0044887424601
ko04137	Mitophagy - animal	2/843	82/7206	0.00491654101052
ko04141	Protein processing in endoplasmic reticulum	10/843	184/7206	0.00506341315778
ko04640	Hematopoietic cell lineage	1/843	64/7206	0.00549338480669
ko04924	Renin secretion	19/843	86/7206	0.00591265320749
ko04918	Thyroid hormone synthesis	19/843	86/7206	0.00591265320749
ko04960	Aldosterone-regulated sodium reabsorption	11/843	41/7206	0.00606642501985
ko05168	Herpes simplex infection	10/843	182/7206	0.00677289955961
ko04612	Antigen processing and presentation	2/843	77/7206	0.00698283394684
ko04973	Carbohydrate digestion and absorption	11/843	42/7206	0.00737216777686
ko04976	Bile secretion	18/843	80/7206	0.00742012190825
ko04350	TGF-beta signaling pathway	4/843	103/7206	0.00830665860255
ko04217	Necroptosis	10/843	178/7206	0.00887795980368
ko04071	Sphingolipid signaling pathway	30/843	162/7206	0.00916410149894
ko04750	Inflammatory mediator regulation of TRP channels	24/843	122/7206	0.00978397765639
ko04923	Regulation of lipolysis in adipocytes	17/843	77/7206	0.0108935815164
ko04740	Olfactory transduction	17/843	80/7206	0.0130117916392
ko04270	Vascular smooth muscle contraction	28/843	154/7206	0.0156006826507
ko04621	NOD-like receptor signaling pathway	9/843	157/7206	0.016448345563
ko05410	Hypertrophic cardiomyopathy (HCM)	20/843	100/7206	0.017207694621
ko05321	Inflammatory bowel disease (IBD)	1/843	56/7206	0.0187290955226
ko05162	Measles	6/843	120/7206	0.0207046617016
ko04912	GnRH signaling pathway	23/843	122/7206	0.0216453505602
ko04666	Fc gamma R-mediated phagocytosis	23/843	122/7206	0.0216453505602
ko04371	Apelin signaling pathway	31/843	177/7206	0.0235092058309
ko00380	Tryptophan metabolism	1/843	50/7206	0.025821964296
ko04140	Autophagy - animal	10/843	164/7206	0.025894481985
ko00590	Arachidonic acid metabolism	1/843	52/7206	0.0269265776394
ko04146	Peroxisome	4/843	89/7206	0.0300966056058
ko00620	Pyruvate metabolism	1/843	46/7206	0.0377906784526
ko00260	Glycine, serine and threonine metabolism	1/843	48/7206	0.0388226750309
ko01212	Fatty acid metabolism	2/843	60/7206	0.0418707363328
ko00310	Lysine degradation	3/843	73/7206	0.0424550690397
ko00330	Arginine and proline metabolism	2/843	61/7206	0.0425069080248
ko00562	Inositol phosphate metabolism	17/843	89/7206	0.0438659350514