ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	17/282	56/7206	1.8149245034e-11
ko04727	GABAergic synapse	22/282	110/7206	1.64763735113e-10
ko04728	Dopaminergic synapse	26/282	185/7206	1.05271671685e-08
ko04721	Synaptic vesicle cycle	16/282	80/7206	5.56721577694e-08
ko04723	Retrograde endocannabinoid signaling	24/282	175/7206	6.45177443074e-08
ko05032	Morphine addiction	18/282	110/7206	2.08020541455e-07
ko04724	Glutamatergic synapse	20/282	152/7206	1.64078032465e-06
ko04080	Neuroactive ligand-receptor interaction	36/282	423/7206	7.53592022109e-06
ko04725	Cholinergic synapse	17/282	160/7206	0.000160160879113
ko04911	Insulin secretion	14/282	117/7206	0.000174912119525
ko04974	Protein digestion and absorption	12/282	96/7206	0.000336802137075
ko04360	Axon guidance	21/282	233/7206	0.000370168686124
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/282	59/7206	0.000425690200645
ko04391	Hippo signaling pathway - fly	11/282	90/7206	0.000719359195491
ko04950	Maturity onset diabetes of the young	6/282	29/7206	0.000755612213
ko04726	Serotonergic synapse	14/282	137/7206	0.000892966745128
ko04512	ECM-receptor interaction	10/282	79/7206	0.000947404816311
ko04514	Cell adhesion molecules (CAMs)	13/282	130/7206	0.0016510959836
ko04713	Circadian entrainment	13/282	136/7206	0.00247767263927
ko05016	Huntington's disease	1/282	215/7206	0.00348371087537
ko04151	PI3K-Akt signaling pathway	27/282	390/7206	0.00426137703317
ko04010	MAPK signaling pathway	23/282	321/7206	0.00459805916921
ko04060	Cytokine-cytokine receptor interaction	1/282	191/7206	0.00718804898739
ko05030	Cocaine addiction	8/282	73/7206	0.00736673592408
ko05203	Viral carcinogenesis	3/282	277/7206	0.0102218018562
ko04024	cAMP signaling pathway	20/282	279/7206	0.0104349469433
ko00430	Taurine and hypotaurine metabolism	3/282	14/7206	0.0156622239737
ko04978	Mineral absorption	5/282	40/7206	0.0189949718474
ko04611	Platelet activation	1/282	163/7206	0.0221006783608
ko04140	Autophagy - animal	1/282	164/7206	0.0222816237347
ko05164	Influenza A	1/282	167/7206	0.0230270402772
ko05014	Amyotrophic lateral sclerosis (ALS)	7/282	74/7206	0.0250911842285
ko04964	Proximal tubule bicarbonate reclamation	4/282	29/7206	0.025221454372
ko05322	Systemic lupus erythematosus	1/282	151/7206	0.0315027989442
ko04730	Long-term depression	7/282	78/7206	0.0323248654425
ko04550	Signaling pathways regulating pluripotency of stem cells	12/282	165/7206	0.0381109844811
ko04261	Adrenergic signaling in cardiomyocytes	14/282	205/7206	0.0413463840667
ko05166	HTLV-I infection	5/282	292/7206	0.0446470522628
ko04120	Ubiquitin mediated proteolysis	1/282	138/7206	0.0449358930032
ko03040	Spliceosome	1/282	145/7206	0.0467498111466
ko04217	Necroptosis	2/282	178/7206	0.0489541568648
ko05168	Herpes simplex infection	2/282	182/7206	0.0496878730212