ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	68/495	145/7206	1.81488143497e-41
ko03008	Ribosome biogenesis in eukaryotes	39/495	79/7206	4.28944663397e-25
ko03013	RNA transport	52/495	166/7206	8.1712356853e-22
ko03030	DNA replication	22/495	38/7206	1.30445224617e-16
ko04110	Cell cycle	38/495	145/7206	2.07090232859e-13
ko03020	RNA polymerase	16/495	29/7206	5.72412028694e-12
ko00240	Pyrimidine metabolism	28/495	110/7206	6.97470354383e-10
ko03050	Proteasome	19/495	54/7206	1.08823685112e-09
ko03015	mRNA surveillance pathway	24/495	93/7206	8.79583382044e-09
ko04111	Cell cycle - yeast	23/495	90/7206	2.20618758643e-08
ko04020	Calcium signaling pathway	1/495	265/7206	1.70540923755e-07
ko03420	Nucleotide excision repair	15/495	46/7206	2.03255534777e-07
ko05169	Epstein-Barr virus infection	34/495	206/7206	1.57382916339e-06
ko04144	Endocytosis	5/495	342/7206	3.04048965792e-06
ko04024	cAMP signaling pathway	3/495	279/7206	5.23380215712e-06
ko03460	Fanconi anemia pathway	14/495	51/7206	5.26321583872e-06
ko03430	Mismatch repair	9/495	22/7206	7.02329446662e-06
ko03018	RNA degradation	18/495	84/7206	1.14845405038e-05
ko04060	Cytokine-cytokine receptor interaction	1/495	191/7206	3.05609239567e-05
ko03410	Base excision repair	11/495	38/7206	3.15141271293e-05
ko00230	Purine metabolism	30/495	194/7206	3.29089430422e-05
ko04022	cGMP-PKG signaling pathway	2/495	216/7206	5.07752423496e-05
ko04810	Regulation of actin cytoskeleton	4/495	264/7206	9.06333912731e-05
ko04261	Adrenergic signaling in cardiomyocytes	2/495	205/7206	0.000108936701191
ko04725	Cholinergic synapse	1/495	160/7206	0.000212119084435
ko04113	Meiosis - yeast	14/495	70/7206	0.000234335313135
ko05012	Parkinson's disease	1/495	155/7206	0.000312913355802
ko03440	Homologous recombination	10/495	41/7206	0.000344107984476
ko04724	Glutamatergic synapse	1/495	152/7206	0.000477671616478
ko04360	Axon guidance	4/495	233/7206	0.000505819994769
ko03010	Ribosome	20/495	129/7206	0.000556493115508
ko04062	Chemokine signaling pathway	3/495	201/7206	0.000595822045913
ko04010	MAPK signaling pathway	8/495	321/7206	0.000624153075621
ko04723	Retrograde endocannabinoid signaling	2/495	175/7206	0.000685807342345
ko04510	Focal adhesion	5/495	240/7206	0.00106907765023
ko04380	Osteoclast differentiation	1/495	134/7206	0.00149098283471
ko04015	Rap1 signaling pathway	7/495	278/7206	0.00155698786337
ko04014	Ras signaling pathway	7/495	279/7206	0.00155789497616
ko04713	Circadian entrainment	1/495	136/7206	0.0015612762336
ko04728	Dopaminergic synapse	3/495	185/7206	0.00171223627802
ko04921	Oxytocin signaling pathway	4/495	209/7206	0.00195324751588
ko04270	Vascular smooth muscle contraction	2/495	154/7206	0.00200255279257
ko04922	Glucagon signaling pathway	1/495	128/7206	0.00217560943189
ko04514	Cell adhesion molecules (CAMs)	1/495	130/7206	0.00227122603621
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/495	182/7206	0.00251716560121
ko00970	Aminoacyl-tRNA biosynthesis	9/495	44/7206	0.00257221566476
ko04668	TNF signaling pathway	1/495	120/7206	0.00311662471496
ko04912	GnRH signaling pathway	1/495	122/7206	0.00317170219069
ko04931	Insulin resistance	2/495	137/7206	0.00585344457856
ko04726	Serotonergic synapse	2/495	137/7206	0.00585344457856
ko04623	Cytosolic DNA-sensing pathway	8/495	41/7206	0.0059555522563
ko04218	Cellular senescence	22/495	177/7206	0.00611279317428
ko04727	GABAergic synapse	1/495	110/7206	0.00671971197752
ko05032	Morphine addiction	1/495	110/7206	0.00671971197752
ko04070	Phosphatidylinositol signaling system	1/495	112/7206	0.00695686903681
ko04915	Estrogen signaling pathway	2/495	131/7206	0.00833138937893
ko05142	Chagas disease (American trypanosomiasis)	2/495	130/7206	0.00833852365679
ko04630	Jak-STAT signaling pathway	2/495	132/7206	0.00836051020999
ko05222	Small cell lung cancer	13/495	89/7206	0.00907307426456
ko04371	Apelin signaling pathway	4/495	177/7206	0.0098080661678
ko04072	Phospholipase D signaling pathway	5/495	197/7206	0.00983084985307
ko05168	Herpes simplex infection	22/495	182/7206	0.0104753096848
ko04151	PI3K-Akt signaling pathway	15/495	390/7206	0.0131282574103
ko04670	Leukocyte transendothelial migration	3/495	151/7206	0.0133303359427
ko05211	Renal cell carcinoma	1/495	96/7206	0.0140275538846
ko04064	NF-kappa B signaling pathway	1/495	96/7206	0.0140275538846
ko05100	Bacterial invasion of epithelial cells	1/495	99/7206	0.0143444275269
ko05146	Amoebiasis	1/495	99/7206	0.0143444275269
ko04620	Toll-like receptor signaling pathway	1/495	100/7206	0.0145963760288
ko03450	Non-homologous end-joining	4/495	15/7206	0.0163386128638
ko04530	Tight junction	7/495	228/7206	0.0163596787311
ko04115	p53 signaling pathway	11/495	74/7206	0.01662568198
ko04666	Fc gamma R-mediated phagocytosis	2/495	122/7206	0.0171122727944
ko03060	Protein export	5/495	23/7206	0.0179408464605
ko04916	Melanogenesis	3/495	142/7206	0.0180413296137
ko04611	Platelet activation	4/495	163/7206	0.018310049235
ko04391	Hippo signaling pathway - fly	1/495	90/7206	0.0203493728124
ko05031	Amphetamine addiction	1/495	91/7206	0.0203854639385
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/495	92/7206	0.020522622314
ko04621	NOD-like receptor signaling pathway	4/495	157/7206	0.0249416229918
ko00562	Inositol phosphate metabolism	1/495	89/7206	0.0310576174157
ko04659	Th17 cell differentiation	2/495	106/7206	0.0332850507421
ko05160	Hepatitis C	4/495	153/7206	0.0341033033598
ko04540	Gap junction	3/495	128/7206	0.0343559084279
ko04972	Pancreatic secretion	2/495	111/7206	0.0344287010531
ko04512	ECM-receptor interaction	1/495	79/7206	0.0426090526802
ko04976	Bile secretion	1/495	80/7206	0.0428453218247
ko05230	Central carbon metabolism in cancer	1/495	81/7206	0.0432725943425
ko04138	Autophagy - yeast	1/495	81/7206	0.0432725943425
ko04520	Adherens junction	2/495	103/7206	0.0471334022525
ko04750	Inflammatory mediator regulation of TRP channels	3/495	122/7206	0.0471437344812
ko04660	T cell receptor signaling pathway	3/495	124/7206	0.0472845033705
ko05145	Toxoplasmosis	3/495	126/7206	0.0479558394958