ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 48/336 145/7206 5.69953010761e-29 ko03022 Basal transcription factors 21/336 44/7206 4.50443065729e-17 ko03013 RNA transport 34/336 166/7206 1.10463204115e-13 ko03420 Nucleotide excision repair 14/336 46/7206 1.08335916617e-08 ko03008 Ribosome biogenesis in eukaryotes 18/336 79/7206 1.40967470966e-08 ko00240 Pyrimidine metabolism 21/336 110/7206 2.49635598119e-08 ko03020 RNA polymerase 11/336 29/7206 3.13015111531e-08 ko04110 Cell cycle 23/336 145/7206 1.95794311425e-07 ko03018 RNA degradation 15/336 84/7206 6.17435412495e-06 ko03410 Base excision repair 9/336 38/7206 4.59120828173e-05 ko03060 Protein export 7/336 23/7206 5.77500335093e-05 ko04111 Cell cycle - yeast 14/336 90/7206 6.30328675861e-05 ko04020 Calcium signaling pathway 1/336 265/7206 7.39934175375e-05 ko04113 Meiosis - yeast 12/336 70/7206 8.01223674476e-05 ko03440 Homologous recombination 9/336 41/7206 8.7174734539e-05 ko04120 Ubiquitin mediated proteolysis 16/336 138/7206 0.000650970124132 ko04921 Oxytocin signaling pathway 1/336 209/7206 0.00073366455752 ko05205 Proteoglycans in cancer 3/336 271/7206 0.00180297298191 ko04360 Axon guidance 2/336 233/7206 0.00221018311374 ko03460 Fanconi anemia pathway 8/336 51/7206 0.00225849141905 ko04060 Cytokine-cytokine receptor interaction 1/336 191/7206 0.00242908830526 ko00230 Purine metabolism 19/336 194/7206 0.00258449491608 ko05203 Viral carcinogenesis 24/336 277/7206 0.00318103838439 ko04371 Apelin signaling pathway 1/336 177/7206 0.00334749758465 ko04130 SNARE interactions in vesicular transport 7/336 44/7206 0.00388489019907 ko04151 PI3K-Akt signaling pathway 7/336 390/7206 0.00408419605344 ko03450 Non-homologous end-joining 4/336 15/7206 0.00420896860559 ko04022 cGMP-PKG signaling pathway 2/336 216/7206 0.00452480249333 ko05224 Breast cancer 1/336 174/7206 0.00515065759878 ko04024 cAMP signaling pathway 4/336 279/7206 0.00540395124372 ko05010 Alzheimer's disease 2/336 202/7206 0.00620443088564 ko04114 Oocyte meiosis 14/336 139/7206 0.00641653213978 ko04725 Cholinergic synapse 1/336 160/7206 0.00708232053312 ko04152 AMPK signaling pathway 1/336 161/7206 0.00711525216389 ko03030 DNA replication 6/336 38/7206 0.00766293399244 ko04914 Progesterone-mediated oocyte maturation 11/336 104/7206 0.00883899377535 ko04072 Phospholipase D signaling pathway 2/336 197/7206 0.00898218189491 ko05169 Epstein-Barr virus infection 18/336 206/7206 0.0104217200158 ko04810 Regulation of actin cytoskeleton 4/336 264/7206 0.0104334948915 ko03015 mRNA surveillance pathway 10/336 93/7206 0.0109952066775 ko04390 Hippo signaling pathway 2/336 188/7206 0.0126837839742 ko05200 Pathways in cancer 12/336 492/7206 0.0141934867046 ko05166 HTLV-I infection 23/336 292/7206 0.0147579924242 ko04916 Melanogenesis 1/336 142/7206 0.0148411391314 ko04144 Endocytosis 7/336 342/7206 0.0170334119639 ko03430 Mismatch repair 4/336 22/7206 0.017441731354 ko04015 Rap1 signaling pathway 5/336 278/7206 0.0189785337571 ko04726 Serotonergic synapse 1/336 137/7206 0.0218691867109 ko05034 Alcoholism 4/336 238/7206 0.026674162616 ko04660 T cell receptor signaling pathway 1/336 124/7206 0.0308929835457 ko05145 Toxoplasmosis 1/336 126/7206 0.0310229889369 ko04514 Cell adhesion molecules (CAMs) 1/336 130/7206 0.032065159367 ko04915 Estrogen signaling pathway 1/336 131/7206 0.0324885292973 ko04621 NOD-like receptor signaling pathway 2/336 157/7206 0.0346925997066 ko04623 Cytosolic DNA-sensing pathway 5/336 41/7206 0.0404830076441 ko04014 Ras signaling pathway 6/336 279/7206 0.0415012527426 ko04911 Insulin secretion 1/336 117/7206 0.0445631739218 ko04668 TNF signaling pathway 1/336 120/7206 0.0454233197177 ko04912 GnRH signaling pathway 1/336 122/7206 0.0464373232979 ko04666 Fc gamma R-mediated phagocytosis 1/336 122/7206 0.0464373232979