ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	40/652	80/7206	1.97957409911e-21
ko04080	Neuroactive ligand-receptor interaction	99/652	423/7206	4.70331580503e-20
ko05033	Nicotine addiction	32/652	56/7206	1.07151254417e-19
ko04724	Glutamatergic synapse	53/652	152/7206	4.43477020213e-19
ko04728	Dopaminergic synapse	57/652	185/7206	1.47432197043e-17
ko04713	Circadian entrainment	47/652	136/7206	7.34046331907e-17
ko05032	Morphine addiction	39/652	110/7206	1.30710837489e-14
ko04725	Cholinergic synapse	48/652	160/7206	1.89309119186e-14
ko04723	Retrograde endocannabinoid signaling	50/652	175/7206	4.5209698645e-14
ko04727	GABAergic synapse	38/652	110/7206	7.53811441054e-14
ko04911	Insulin secretion	38/652	117/7206	6.9858583246e-13
ko04024	cAMP signaling pathway	60/652	279/7206	1.43061928393e-10
ko04921	Oxytocin signaling pathway	49/652	209/7206	2.23475466161e-10
ko04726	Serotonergic synapse	35/652	137/7206	8.60235942154e-09
ko04970	Salivary secretion	28/652	95/7206	9.27394697838e-09
ko04261	Adrenergic signaling in cardiomyocytes	45/652	205/7206	1.40737831603e-08
ko05031	Amphetamine addiction	27/652	91/7206	1.46067695852e-08
ko04720	Long-term potentiation	26/652	99/7206	4.03791240123e-07
ko04020	Calcium signaling pathway	50/652	265/7206	4.99593143505e-07
ko04744	Phototransduction	14/652	36/7206	1.23753880908e-06
ko05030	Cocaine addiction	20/652	73/7206	4.3689632641e-06
ko04966	Collecting duct acid secretion	11/652	26/7206	6.66331739723e-06
ko05203	Viral carcinogenesis	7/652	277/7206	1.51100686419e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	19/652	74/7206	2.09639720501e-05
ko03040	Spliceosome	1/652	145/7206	2.61409137082e-05
ko04060	Cytokine-cytokine receptor interaction	3/652	191/7206	2.97040929651e-05
ko04514	Cell adhesion molecules (CAMs)	27/652	130/7206	3.34372693646e-05
ko04360	Axon guidance	41/652	233/7206	3.48993361318e-05
ko04971	Gastric acid secretion	22/652	98/7206	4.65682200042e-05
ko04742	Taste transduction	16/652	61/7206	7.06262096927e-05
ko04745	Phototransduction - fly	12/652	38/7206	8.11292039345e-05
ko05322	Systemic lupus erythematosus	2/652	151/7206	0.000138156010575
ko04022	cGMP-PKG signaling pathway	37/652	216/7206	0.000146095463054
ko04730	Long-term depression	18/652	78/7206	0.00015495806667
ko05164	Influenza A	3/652	167/7206	0.000182736861669
ko04010	MAPK signaling pathway	49/652	321/7206	0.000207628290136
ko05162	Measles	1/652	120/7206	0.000286849455838
ko05168	Herpes simplex infection	4/652	182/7206	0.000325581090961
ko04972	Pancreatic secretion	22/652	111/7206	0.00034659802849
ko05110	Vibrio cholerae infection	15/652	63/7206	0.000377101733329
ko04120	Ubiquitin mediated proteolysis	2/652	138/7206	0.000428930002223
ko04260	Cardiac muscle contraction	20/652	98/7206	0.000485084973261
ko04964	Proximal tubule bicarbonate reclamation	9/652	29/7206	0.000733895200729
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/652	14/7206	0.000853935375127
ko03013	RNA transport	4/652	166/7206	0.000892443327009
ko04925	Aldosterone synthesis and secretion	20/652	105/7206	0.00151572228876
ko04924	Renin secretion	17/652	86/7206	0.00181600765812
ko04070	Phosphatidylinositol signaling system	20/652	112/7206	0.0025541196825
ko04630	Jak-STAT signaling pathway	3/652	132/7206	0.00315463580755
ko05010	Alzheimer's disease	31/652	202/7206	0.00380096965377
ko04626	Plant-pathogen interaction	6/652	18/7206	0.0038540392972
ko05205	Proteoglycans in cancer	12/652	271/7206	0.00479158678838
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/652	92/7206	0.00485093142935
ko04510	Focal adhesion	10/652	240/7206	0.0056326973928
ko05169	Epstein-Barr virus infection	8/652	206/7206	0.00629584068024
ko04621	NOD-like receptor signaling pathway	5/652	157/7206	0.00687123337066
ko04540	Gap junction	21/652	128/7206	0.00726511350326
ko04141	Protein processing in endoplasmic reticulum	7/652	184/7206	0.00877062674901
ko04612	Antigen processing and presentation	1/652	77/7206	0.00897508269915
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/652	59/7206	0.00938020648817
ko04064	NF-kappa B signaling pathway	2/652	96/7206	0.0111063352176
ko00310	Lysine degradation	1/652	73/7206	0.0131015708398
ko05323	Rheumatoid arthritis	15/652	89/7206	0.0150698196288
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/652	79/7206	0.0153167653155
ko05166	HTLV-I infection	15/652	292/7206	0.0161128717637
ko04114	Oocyte meiosis	21/652	139/7206	0.0165284086276
ko05215	Prostate cancer	3/652	111/7206	0.0177561566584
ko04214	Apoptosis - fly	1/652	72/7206	0.0201540702446
ko05220	Chronic myeloid leukemia	2/652	85/7206	0.0223352772417
ko04146	Peroxisome	2/652	89/7206	0.0231968933445
ko04668	TNF signaling pathway	4/652	120/7206	0.0237065975909
ko04978	Mineral absorption	8/652	40/7206	0.0245842193836
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/652	182/7206	0.0251953074598
ko04014	Ras signaling pathway	36/652	279/7206	0.0254439313287
ko04145	Phagosome	23/652	162/7206	0.0262374849939
ko00190	Oxidative phosphorylation	19/652	127/7206	0.0273837961175
ko04640	Hematopoietic cell lineage	1/652	64/7206	0.0278388684209
ko04960	Aldosterone-regulated sodium reabsorption	8/652	41/7206	0.0282108426905
ko04740	Olfactory transduction	13/652	80/7206	0.030791744378
ko04750	Inflammatory mediator regulation of TRP channels	18/652	122/7206	0.0366840508652
ko04110	Cell cycle	6/652	145/7206	0.0390682360125
ko00330	Arginine and proline metabolism	1/652	61/7206	0.0408447854381
ko01200	Carbon metabolism	5/652	128/7206	0.0417244653518
ko00561	Glycerolipid metabolism	1/652	63/7206	0.0425099179669
ko05161	Hepatitis B	8/652	173/7206	0.0428409719118
ko04915	Estrogen signaling pathway	19/652	131/7206	0.0434022040161
ko00240	Pyrimidine metabolism	4/652	110/7206	0.0437298236477
ko01524	Platinum drug resistance	2/652	76/7206	0.0444988026172