ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	62/617	152/7206	7.58228292656e-28
ko04727	GABAergic synapse	51/617	110/7206	3.2254694728e-26
ko05033	Nicotine addiction	36/617	56/7206	2.19023013294e-25
ko05032	Morphine addiction	50/617	110/7206	3.17080978619e-25
ko04080	Neuroactive ligand-receptor interaction	101/617	423/7206	4.97387829257e-23
ko04744	Phototransduction	27/617	36/7206	3.9948104209e-22
ko04723	Retrograde endocannabinoid signaling	58/617	175/7206	9.49954463455e-21
ko04713	Circadian entrainment	46/617	136/7206	4.73361037349e-17
ko04728	Dopaminergic synapse	50/617	185/7206	5.56710193369e-14
ko04721	Synaptic vesicle cycle	30/617	80/7206	7.05155105698e-13
ko04725	Cholinergic synapse	42/617	160/7206	1.78304847021e-11
ko04024	cAMP signaling pathway	59/617	279/7206	3.54819406741e-11
ko04740	Olfactory transduction	27/617	80/7206	1.72272776998e-10
ko04911	Insulin secretion	33/617	117/7206	3.6250839486e-10
ko04921	Oxytocin signaling pathway	45/617	209/7206	3.82216753949e-09
ko04726	Serotonergic synapse	34/617	137/7206	7.66048342528e-09
ko05030	Cocaine addiction	23/617	73/7206	1.77017766658e-08
ko04742	Taste transduction	20/617	61/7206	7.20997343006e-08
ko05203	Viral carcinogenesis	4/617	277/7206	4.83717488716e-07
ko04261	Adrenergic signaling in cardiomyocytes	39/617	205/7206	1.47488207989e-06
ko05031	Amphetamine addiction	23/617	91/7206	1.49252646833e-06
ko04970	Salivary secretion	23/617	95/7206	3.32435105298e-06
ko05205	Proteoglycans in cancer	5/617	271/7206	3.97028169201e-06
ko04720	Long-term potentiation	23/617	99/7206	7.0219028843e-06
ko05164	Influenza A	1/617	167/7206	8.23710299508e-06
ko04020	Calcium signaling pathway	44/617	265/7206	1.54300478385e-05
ko04060	Cytokine-cytokine receptor interaction	3/617	191/7206	6.3201411544e-05
ko05169	Epstein-Barr virus infection	4/617	206/7206	0.000115626903936
ko05168	Herpes simplex infection	3/617	182/7206	0.000131607140964
ko04972	Pancreatic secretion	22/617	111/7206	0.00019075252971
ko04260	Cardiac muscle contraction	20/617	98/7206	0.000191604587628
ko05161	Hepatitis B	3/617	173/7206	0.000272829973214
ko05322	Systemic lupus erythematosus	2/617	151/7206	0.000307765220671
ko04022	cGMP-PKG signaling pathway	34/617	216/7206	0.000455584684827
ko05166	HTLV-I infection	10/617	292/7206	0.000573397434029
ko05034	Alcoholism	36/617	238/7206	0.000833686085175
ko04010	MAPK signaling pathway	45/617	321/7206	0.000981960045072
ko05014	Amyotrophic lateral sclerosis (ALS)	15/617	74/7206	0.00127303621327
ko04072	Phospholipase D signaling pathway	30/617	197/7206	0.00172231895951
ko03013	RNA transport	4/617	166/7206	0.00179834006667
ko04141	Protein processing in endoplasmic reticulum	5/617	184/7206	0.00192905231254
ko04510	Focal adhesion	8/617	240/7206	0.00204201503454
ko04514	Cell adhesion molecules (CAMs)	22/617	130/7206	0.0021269782082
ko04925	Aldosterone synthesis and secretion	19/617	105/7206	0.00215550002148
ko04668	TNF signaling pathway	2/617	120/7206	0.00268603014522
ko04730	Long-term depression	15/617	78/7206	0.00310578220056
ko04120	Ubiquitin mediated proteolysis	3/617	138/7206	0.00318171368102
ko04810	Regulation of actin cytoskeleton	10/617	264/7206	0.00329470840514
ko05418	Fluid shear stress and atherosclerosis	5/617	173/7206	0.00365871337822
ko04218	Cellular senescence	5/617	177/7206	0.00379510451994
ko04745	Phototransduction - fly	9/617	38/7206	0.00396334830875
ko04630	Jak-STAT signaling pathway	3/617	132/7206	0.00448810343145
ko04966	Collecting duct acid secretion	7/617	26/7206	0.00506379896983
ko05215	Prostate cancer	2/617	111/7206	0.00554252079667
ko04110	Cell cycle	4/617	145/7206	0.00673114931032
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/617	182/7206	0.00684253199493
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/617	79/7206	0.00739802580691
ko04660	T cell receptor signaling pathway	3/617	124/7206	0.00886521746536
ko04210	Apoptosis	6/617	180/7206	0.00954093240114
ko04971	Gastric acid secretion	16/617	98/7206	0.0100905201928
ko04620	Toll-like receptor signaling pathway	2/617	100/7206	0.0112260136562
ko04350	TGF-beta signaling pathway	2/617	103/7206	0.0115351136948
ko05224	Breast cancer	6/617	174/7206	0.0126406230569
ko04621	NOD-like receptor signaling pathway	5/617	157/7206	0.0131213794897
ko04371	Apelin signaling pathway	25/617	177/7206	0.0133309112921
ko04610	Complement and coagulation cascades	1/617	79/7206	0.0135023564148
ko03008	Ribosome biogenesis in eukaryotes	1/617	79/7206	0.0135023564148
ko05211	Renal cell carcinoma	2/617	96/7206	0.0159807943713
ko04070	Phosphatidylinositol signaling system	17/617	112/7206	0.0167798080401
ko05414	Dilated cardiomyopathy	17/617	112/7206	0.0167798080401
ko04670	Leukocyte transendothelial migration	5/617	151/7206	0.0175194681279
ko00230	Purine metabolism	26/617	194/7206	0.0189456200807
ko04214	Apoptosis - fly	1/617	72/7206	0.0194088334016
ko04062	Chemokine signaling pathway	27/617	201/7206	0.0202620565155
ko01524	Platinum drug resistance	1/617	76/7206	0.0204058608776
ko04014	Ras signaling pathway	35/617	279/7206	0.0212409274592
ko04140	Autophagy - animal	6/617	164/7206	0.0226023693179
ko04550	Signaling pathways regulating pluripotency of stem cells	6/617	165/7206	0.0229008109578
ko04976	Bile secretion	13/617	80/7206	0.0239309448804
ko05206	MicroRNAs in cancer	7/617	177/7206	0.0281294627071
ko05218	Melanoma	2/617	85/7206	0.0319779880787
ko05220	Chronic myeloid leukemia	2/617	85/7206	0.0319779880787
ko04657	IL-17 signaling pathway	2/617	87/7206	0.0321385185904
ko05133	Pertussis	2/617	87/7206	0.0321385185904
ko05222	Small cell lung cancer	2/617	89/7206	0.0330430979361
ko04964	Proximal tubule bicarbonate reclamation	6/617	29/7206	0.0333302746182
ko04910	Insulin signaling pathway	7/617	172/7206	0.0369185037682
ko05160	Hepatitis C	6/617	153/7206	0.0394051811532
ko04640	Hematopoietic cell lineage	1/617	64/7206	0.0411394744964
ko04931	Insulin resistance	5/617	137/7206	0.0429085143713
ko04150	mTOR signaling pathway	8/617	184/7206	0.04368552299
ko04137	Mitophagy - animal	2/617	82/7206	0.0451978442792
ko05132	Salmonella infection	3/617	98/7206	0.0455231689713
ko03018	RNA degradation	2/617	84/7206	0.0463443728007
ko04611	Platelet activation	7/617	163/7206	0.0470814911189
ko04924	Renin secretion	13/617	86/7206	0.0484677349