ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 29/283 157/7206 1.57820462816e-12 ko04060 Cytokine-cytokine receptor interaction 30/283 191/7206 4.7224369787e-11 ko04380 Osteoclast differentiation 25/283 134/7206 4.72376993951e-11 ko05164 Influenza A 26/283 167/7206 1.21569662442e-09 ko04064 NF-kappa B signaling pathway 18/283 96/7206 2.47645235767e-08 ko04217 Necroptosis 24/283 178/7206 9.60741920346e-08 ko05133 Pertussis 16/283 87/7206 2.00427478741e-07 ko05145 Toxoplasmosis 19/283 126/7206 3.78402173901e-07 ko05162 Measles 18/283 120/7206 8.37491201854e-07 ko04620 Toll-like receptor signaling pathway 16/283 100/7206 1.43494023002e-06 ko04623 Cytosolic DNA-sensing pathway 10/283 41/7206 2.83311134837e-06 ko05131 Shigellosis 14/283 82/7206 2.98816786571e-06 ko04062 Chemokine signaling pathway 23/283 201/7206 3.38662763197e-06 ko04668 TNF signaling pathway 17/283 120/7206 3.82010593964e-06 ko04622 RIG-I-like receptor signaling pathway 12/283 62/7206 3.96609990197e-06 ko04666 Fc gamma R-mediated phagocytosis 17/283 122/7206 4.80978960242e-06 ko04660 T cell receptor signaling pathway 17/283 124/7206 6.0241241965e-06 ko05168 Herpes simplex infection 21/283 182/7206 8.02750404305e-06 ko05161 Hepatitis B 20/283 173/7206 1.28841599203e-05 ko04650 Natural killer cell mediated cytotoxicity 14/283 97/7206 2.23616294922e-05 ko05132 Salmonella infection 14/283 98/7206 2.51828582715e-05 ko04657 IL-17 signaling pathway 13/283 87/7206 3.01706055028e-05 ko05140 Leishmaniasis 12/283 75/7206 3.0370723815e-05 ko05340 Primary immunodeficiency 7/283 30/7206 0.000125044872391 ko05152 Tuberculosis 19/283 187/7206 0.000126713163898 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/283 191/7206 0.000167729663425 ko05160 Hepatitis C 16/283 153/7206 0.000311464130405 ko04658 Th1 and Th2 cell differentiation 12/283 96/7206 0.000347877291594 ko05150 Staphylococcus aureus infection 7/283 36/7206 0.000418868601429 ko04672 Intestinal immune network for IgA production 7/283 37/7206 0.000499516502437 ko04662 B cell receptor signaling pathway 11/283 88/7206 0.000610951733404 ko04630 Jak-STAT signaling pathway 14/283 132/7206 0.000637377754077 ko04670 Leukocyte transendothelial migration 15/283 151/7206 0.000823359892418 ko05321 Inflammatory bowel disease (IBD) 8/283 56/7206 0.00141082360586 ko05134 Legionellosis 9/283 74/7206 0.00229857409034 ko05323 Rheumatoid arthritis 10/283 89/7206 0.0024342460625 ko04659 Th17 cell differentiation 11/283 106/7206 0.00284231316975 ko04610 Complement and coagulation cascades 9/283 79/7206 0.00360891259124 ko00140 Steroid hormone biosynthesis 6/283 41/7206 0.0049107243528 ko05100 Bacterial invasion of epithelial cells 10/283 99/7206 0.00529006671114 ko00051 Fructose and mannose metabolism 6/283 42/7206 0.00554474093065 ko04390 Hippo signaling pathway 1/283 188/7206 0.00716163953815 ko00643 Styrene degradation 2/283 4/7206 0.00875004601277 ko04080 Neuroactive ligand-receptor interaction 7/283 423/7206 0.00944965202043 ko04215 Apoptosis - multiple species 6/283 47/7206 0.00964042935977 ko05120 Epithelial cell signaling in Helicobacter pylori infection 9/283 92/7206 0.00979310489188 ko05130 Pathogenic Escherichia coli infection 8/283 77/7206 0.0102927369078 ko04664 Fc epsilon RI signaling pathway 8/283 77/7206 0.0102927369078 ko04728 Dopaminergic synapse 1/283 185/7206 0.0108034974906 ko04640 Hematopoietic cell lineage 7/283 64/7206 0.0122470864302 ko04611 Platelet activation 13/283 163/7206 0.0129768426195 ko05224 Breast cancer 1/283 174/7206 0.0154900318991 ko04210 Apoptosis 14/283 180/7206 0.0168451751655 ko05142 Chagas disease (American trypanosomiasis) 11/283 130/7206 0.018207853033 ko05416 Viral myocarditis 6/283 55/7206 0.0200749085217 ko04144 Endocytosis 22/283 342/7206 0.0213382753973 ko04550 Signaling pathways regulating pluripotency of stem cells 1/283 165/7206 0.0226333899323 ko05034 Alcoholism 3/283 238/7206 0.0261856676351 ko04130 SNARE interactions in vesicular transport 5/283 44/7206 0.0280186322251 ko05144 Malaria 5/283 45/7206 0.0305452723466 ko04612 Antigen processing and presentation 7/283 77/7206 0.0309094660678 ko05012 Parkinson's disease 1/283 155/7206 0.032653221709 ko04512 ECM-receptor interaction 7/283 79/7206 0.0348982152093 ko04145 Phagosome 12/283 162/7206 0.0363109795419 ko04514 Cell adhesion molecules (CAMs) 10/283 130/7206 0.0366802098091 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/283 135/7206 0.0435373613454 ko04713 Circadian entrainment 1/283 136/7206 0.0449397218595 ko05016 Huntington's disease 3/283 215/7206 0.0491378721304 ko04310 Wnt signaling pathway 2/283 181/7206 0.049582359873