ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	169/1042	423/7206	1.18701627206e-40
ko04721	Synaptic vesicle cycle	57/1042	80/7206	8.48038036784e-31
ko04724	Glutamatergic synapse	80/1042	152/7206	4.31736836629e-29
ko05033	Nicotine addiction	45/1042	56/7206	2.09986947711e-28
ko05032	Morphine addiction	59/1042	110/7206	2.94246473334e-22
ko04713	Circadian entrainment	66/1042	136/7206	1.33024770664e-21
ko04727	GABAergic synapse	58/1042	110/7206	2.08647540556e-21
ko04728	Dopaminergic synapse	78/1042	185/7206	1.45081359797e-20
ko04725	Cholinergic synapse	68/1042	160/7206	2.78281624441e-18
ko04723	Retrograde endocannabinoid signaling	70/1042	175/7206	4.50259730121e-17
ko04742	Taste transduction	36/1042	61/7206	7.74678333843e-16
ko04024	cAMP signaling pathway	90/1042	279/7206	1.22174059164e-14
ko04744	Phototransduction	25/1042	36/7206	9.46729371511e-14
ko04726	Serotonergic synapse	55/1042	137/7206	9.62257405135e-14
ko04911	Insulin secretion	46/1042	117/7206	2.51005964814e-11
ko04921	Oxytocin signaling pathway	66/1042	209/7206	1.66957091417e-10
ko05031	Amphetamine addiction	38/1042	91/7206	1.71839625498e-10
ko04020	Calcium signaling pathway	77/1042	265/7206	3.74481918296e-10
ko04720	Long-term potentiation	39/1042	99/7206	7.83470779163e-10
ko04261	Adrenergic signaling in cardiomyocytes	62/1042	205/7206	3.91469477669e-09
ko04966	Collecting duct acid secretion	17/1042	26/7206	4.02292491199e-09
ko05030	Cocaine addiction	30/1042	73/7206	2.27608193905e-08
ko05203	Viral carcinogenesis	12/1042	277/7206	4.26967747452e-08
ko03040	Spliceosome	2/1042	145/7206	6.44076418691e-08
ko04970	Salivary secretion	34/1042	95/7206	1.56889860649e-07
ko04740	Olfactory transduction	30/1042	80/7206	2.60173161599e-07
ko04060	Cytokine-cytokine receptor interaction	6/1042	191/7206	3.17303349745e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1042	74/7206	5.25205626686e-07
ko05168	Herpes simplex infection	6/1042	182/7206	9.53603782362e-07
ko04360	Axon guidance	61/1042	233/7206	1.67258016727e-06
ko04925	Aldosterone synthesis and secretion	34/1042	105/7206	3.53179201598e-06
ko04971	Gastric acid secretion	32/1042	98/7206	3.87005137688e-06
ko03013	RNA transport	6/1042	166/7206	5.81767751713e-06
ko05164	Influenza A	6/1042	167/7206	5.85178762977e-06
ko04120	Ubiquitin mediated proteolysis	4/1042	138/7206	1.21500866484e-05
ko04010	MAPK signaling pathway	75/1042	321/7206	1.41841807631e-05
ko04924	Renin secretion	28/1042	86/7206	1.70239357616e-05
ko04540	Gap junction	37/1042	128/7206	1.94812702396e-05
ko05110	Vibrio cholerae infection	22/1042	63/7206	3.76987182259e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	21/1042	59/7206	4.07207480968e-05
ko04141	Protein processing in endoplasmic reticulum	9/1042	184/7206	4.41356985152e-05
ko05322	Systemic lupus erythematosus	6/1042	151/7206	5.1975090152e-05
ko04730	Long-term depression	25/1042	78/7206	6.42121843943e-05
ko04514	Cell adhesion molecules (CAMs)	36/1042	130/7206	7.22271334283e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1042	14/7206	0.000248108281756
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/1042	79/7206	0.000270578261189
ko04621	NOD-like receptor signaling pathway	8/1042	157/7206	0.000313625868651
ko05162	Measles	5/1042	120/7206	0.000362886219855
ko05205	Proteoglycans in cancer	20/1042	271/7206	0.000393823991987
ko04745	Phototransduction - fly	14/1042	38/7206	0.000518676594528
ko04022	cGMP-PKG signaling pathway	50/1042	216/7206	0.000530583780521
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/1042	182/7206	0.000558891759386
ko04260	Cardiac muscle contraction	27/1042	98/7206	0.000698343386607
ko03008	Ribosome biogenesis in eukaryotes	2/1042	79/7206	0.000987762944891
ko04972	Pancreatic secretion	29/1042	111/7206	0.00100248766605
ko04146	Peroxisome	3/1042	89/7206	0.00118332452587
ko04014	Ras signaling pathway	60/1042	279/7206	0.001235669228
ko05120	Epithelial cell signaling in Helicobacter pylori infection	25/1042	92/7206	0.00141524203053
ko05169	Epstein-Barr virus infection	15/1042	206/7206	0.00176184231056
ko04064	NF-kappa B signaling pathway	4/1042	96/7206	0.00188862641969
ko04626	Plant-pathogen interaction	8/1042	18/7206	0.002110404229
ko04915	Estrogen signaling pathway	32/1042	131/7206	0.00234205008717
ko03018	RNA degradation	3/1042	84/7206	0.00252013752533
ko04750	Inflammatory mediator regulation of TRP channels	30/1042	122/7206	0.00259740496152
ko05161	Hepatitis B	12/1042	173/7206	0.00295184232689
ko00280	Valine, leucine and isoleucine degradation	1/1042	54/7206	0.00325134683874
ko00480	Glutathione metabolism	1/1042	55/7206	0.0032533162207
ko00240	Pyrimidine metabolism	6/1042	110/7206	0.00394383300767
ko00590	Arachidonic acid metabolism	1/1042	52/7206	0.00484672268934
ko04612	Antigen processing and presentation	3/1042	77/7206	0.00497119254824
ko01200	Carbon metabolism	8/1042	128/7206	0.00506309306895
ko04964	Proximal tubule bicarbonate reclamation	10/1042	29/7206	0.005609871275
ko04976	Bile secretion	21/1042	80/7206	0.0057123054706
ko05414	Dilated cardiomyopathy	27/1042	112/7206	0.00622311329887
ko04640	Hematopoietic cell lineage	2/1042	64/7206	0.00636500494394
ko00310	Lysine degradation	3/1042	73/7206	0.00701973122712
ko05140	Leishmaniasis	3/1042	75/7206	0.00726538022422
ko04110	Cell cycle	10/1042	145/7206	0.00813500277565
ko05166	HTLV-I infection	27/1042	292/7206	0.00830535472386
ko04350	TGF-beta signaling pathway	6/1042	103/7206	0.0102837356812
ko03420	Nucleotide excision repair	1/1042	46/7206	0.0107334338604
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/1042	15/7206	0.0140338742003
ko05034	Alcoholism	48/1042	238/7206	0.014486997275
ko03022	Basal transcription factors	1/1042	44/7206	0.0161202929897
ko00071	Fatty acid degradation	1/1042	45/7206	0.0167070811071
ko05321	Inflammatory bowel disease (IBD)	2/1042	56/7206	0.0197386661486
ko05323	Rheumatoid arthritis	21/1042	89/7206	0.0215011169639
ko04145	Phagosome	34/1042	162/7206	0.0231202930542
ko04072	Phospholipase D signaling pathway	40/1042	197/7206	0.023325960258
ko04630	Jak-STAT signaling pathway	10/1042	132/7206	0.0236540942514
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1042	40/7206	0.0236541659619
ko04214	Apoptosis - fly	4/1042	72/7206	0.0277533732811
ko00330	Arginine and proline metabolism	3/1042	61/7206	0.0280670389747
ko00561	Glycerolipid metabolism	3/1042	63/7206	0.0287076429879
ko04115	p53 signaling pathway	4/1042	74/7206	0.0287566994992
ko04371	Apelin signaling pathway	36/1042	177/7206	0.0299504372541
ko04140	Autophagy - animal	14/1042	164/7206	0.0319729554957
ko00982	Drug metabolism - cytochrome P450	1/1042	37/7206	0.0350205623331
ko03320	PPAR signaling pathway	4/1042	69/7206	0.0381826276781
ko05219	Bladder cancer	2/1042	48/7206	0.038713304581
ko05206	MicroRNAs in cancer	16/1042	177/7206	0.0392013029464
ko04217	Necroptosis	16/1042	178/7206	0.0394901352907
ko00380	Tryptophan metabolism	2/1042	50/7206	0.0402645089061
ko04070	Phosphatidylinositol signaling system	24/1042	112/7206	0.0415526357228
ko04015	Rap1 signaling pathway	52/1042	278/7206	0.0452002466621
ko04391	Hippo signaling pathway - fly	20/1042	90/7206	0.0480322522247
ko01524	Platinum drug resistance	5/1042	76/7206	0.04877952546