ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	57/532	152/7206	8.46064725871e-27
ko05033	Nicotine addiction	32/532	56/7206	2.03609335383e-22
ko04727	GABAergic synapse	44/532	110/7206	3.32745799666e-22
ko04728	Dopaminergic synapse	53/532	185/7206	8.79123231469e-19
ko05032	Morphine addiction	40/532	110/7206	1.65595206676e-18
ko04723	Retrograde endocannabinoid signaling	50/532	175/7206	1.02629213857e-17
ko04713	Circadian entrainment	40/532	136/7206	7.49680969492e-15
ko04721	Synaptic vesicle cycle	28/532	80/7206	7.86608709623e-13
ko04080	Neuroactive ligand-receptor interaction	73/532	423/7206	2.10224377441e-12
ko04725	Cholinergic synapse	39/532	160/7206	1.18509489855e-11
ko05030	Cocaine addiction	23/532	73/7206	1.00616907128e-09
ko04911	Insulin secretion	29/532	117/7206	3.65768129879e-09
ko04024	cAMP signaling pathway	48/532	279/7206	2.64074790705e-08
ko04261	Adrenergic signaling in cardiomyocytes	38/532	205/7206	8.14633141364e-08
ko05031	Amphetamine addiction	22/532	91/7206	4.62599361865e-07
ko04720	Long-term potentiation	23/532	99/7206	5.45773202491e-07
ko04072	Phospholipase D signaling pathway	35/532	197/7206	9.95144362174e-07
ko04010	MAPK signaling pathway	48/532	321/7206	1.7491559845e-06
ko04514	Cell adhesion molecules (CAMs)	26/532	130/7206	2.18651056574e-06
ko04742	Taste transduction	16/532	61/7206	5.55714435551e-06
ko04726	Serotonergic synapse	26/532	137/7206	6.05540325779e-06
ko04020	Calcium signaling pathway	39/532	265/7206	3.2904402442e-05
ko04972	Pancreatic secretion	21/532	111/7206	4.96926653303e-05
ko04970	Salivary secretion	19/532	95/7206	5.11630776317e-05
ko05203	Viral carcinogenesis	5/532	277/7206	5.12670067881e-05
ko04360	Axon guidance	35/532	233/7206	5.43930155387e-05
ko04060	Cytokine-cytokine receptor interaction	2/532	191/7206	0.00010646707772
ko04921	Oxytocin signaling pathway	31/532	209/7206	0.000215437165722
ko04915	Estrogen signaling pathway	22/532	131/7206	0.000248525886747
ko05014	Amyotrophic lateral sclerosis (ALS)	15/532	74/7206	0.000267326267456
ko03040	Spliceosome	1/532	145/7206	0.000306334835327
ko04022	cGMP-PKG signaling pathway	30/532	216/7206	0.000782643872271
ko05414	Dilated cardiomyopathy	18/532	112/7206	0.0014833725249
ko04730	Long-term depression	14/532	78/7206	0.00150631874393
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/532	79/7206	0.00171005671755
ko04925	Aldosterone synthesis and secretion	17/532	105/7206	0.00192654543596
ko03013	RNA transport	3/532	166/7206	0.00236441869024
ko05168	Herpes simplex infection	4/532	182/7206	0.00367075344905
ko04930	Type II diabetes mellitus	10/532	54/7206	0.00548857448816
ko04062	Chemokine signaling pathway	26/532	201/7206	0.0055546259041
ko01200	Carbon metabolism	2/532	128/7206	0.00576212506633
ko05205	Proteoglycans in cancer	9/532	271/7206	0.0062002891611
ko05034	Alcoholism	29/532	238/7206	0.00749999540271
ko04371	Apelin signaling pathway	23/532	177/7206	0.00791035955657
ko00515	Mannose type O-glycan biosynthesis	6/532	25/7206	0.00830570507267
ko04540	Gap junction	18/532	128/7206	0.00905178268436
ko04144	Endocytosis	38/532	342/7206	0.0105495925605
ko04621	NOD-like receptor signaling pathway	4/532	157/7206	0.0132197525945
ko04015	Rap1 signaling pathway	32/532	278/7206	0.013297215895
ko04146	Peroxisome	1/532	89/7206	0.0138218078488
ko04744	Phototransduction	7/532	36/7206	0.0146471882653
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/532	14/7206	0.0161958227655
ko00240	Pyrimidine metabolism	2/532	110/7206	0.0165209713413
ko04260	Cardiac muscle contraction	14/532	98/7206	0.0169592610917
ko04014	Ras signaling pathway	31/532	279/7206	0.0192591907223
ko01230	Biosynthesis of amino acids	1/532	85/7206	0.0201367099473
ko05164	Influenza A	5/532	167/7206	0.0239702567415
ko05110	Vibrio cholerae infection	10/532	63/7206	0.0239750549281
ko04940	Type I diabetes mellitus	6/532	32/7206	0.0274397069558
ko05231	Choline metabolism in cancer	17/532	134/7206	0.0279732426789
ko03008	Ribosome biogenesis in eukaryotes	1/532	79/7206	0.0291188648846
ko04213	Longevity regulating pathway - multiple species	12/532	86/7206	0.0337724575239
ko04350	TGF-beta signaling pathway	2/532	103/7206	0.0338782751757
ko04066	HIF-1 signaling pathway	3/532	123/7206	0.0346002765116
ko04110	Cell cycle	4/532	145/7206	0.0347149861607
ko04962	Vasopressin-regulated water reabsorption	9/532	58/7206	0.0366195512056
ko04966	Collecting duct acid secretion	5/532	26/7206	0.0388117142036
ko04217	Necroptosis	6/532	178/7206	0.040489835062
ko00310	Lysine degradation	1/532	73/7206	0.0420787992013
ko00010	Glycolysis / Gluconeogenesis	1/532	74/7206	0.0422258817552
ko04612	Antigen processing and presentation	1/532	77/7206	0.0439872909462
ko04070	Phosphatidylinositol signaling system	14/532	112/7206	0.0443157778888
ko05213	Endometrial cancer	9/532	62/7206	0.045383498969
ko04071	Sphingolipid signaling pathway	19/532	162/7206	0.0459381314074
ko04120	Ubiquitin mediated proteolysis	4/532	138/7206	0.046164060146