ko pathway ratio_in_study ratio_in_pop p_value ko04721 Synaptic vesicle cycle 12/105 80/7206 1.27980972495e-09 ko05033 Nicotine addiction 8/105 56/7206 1.23706645633e-06 ko04724 Glutamatergic synapse 12/105 152/7206 1.81200276405e-06 ko04728 Dopaminergic synapse 13/105 185/7206 2.4448588491e-06 ko04727 GABAergic synapse 10/105 110/7206 3.90789602495e-06 ko04723 Retrograde endocannabinoid signaling 11/105 175/7206 4.35267863234e-05 ko04725 Cholinergic synapse 10/105 160/7206 0.000103522846817 ko05032 Morphine addiction 8/105 110/7206 0.000186505996432 ko04911 Insulin secretion 7/105 117/7206 0.00152315641131 ko04961 Endocrine and other factor-regulated calcium reabsorption 5/105 59/7206 0.00160086038364 ko04514 Cell adhesion molecules (CAMs) 7/105 130/7206 0.00278138582804 ko04261 Adrenergic signaling in cardiomyocytes 9/105 205/7206 0.00290312469315 ko04726 Serotonergic synapse 7/105 137/7206 0.00372780196251 ko04010 MAPK signaling pathway 11/105 321/7206 0.00681893763912 ko04964 Proximal tubule bicarbonate reclamation 3/105 29/7206 0.00834262966469 ko04940 Type I diabetes mellitus 3/105 32/7206 0.0109734551118 ko04260 Cardiac muscle contraction 5/105 98/7206 0.0139086997923 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/105 1/7206 0.0145711906745 ko04360 Axon guidance 8/105 233/7206 0.0200329516859 ko04978 Mineral absorption 3/105 40/7206 0.0201045759062 ko04960 Aldosterone-regulated sodium reabsorption 3/105 41/7206 0.0214668774725 ko05014 Amyotrophic lateral sclerosis (ALS) 4/105 74/7206 0.0224815625651 ko04972 Pancreatic secretion 5/105 111/7206 0.0226540189396 ko04973 Carbohydrate digestion and absorption 3/105 42/7206 0.0228786525699 ko04071 Sphingolipid signaling pathway 6/105 162/7206 0.0305469587509 ko04080 Neuroactive ligand-receptor interaction 12/105 423/7206 0.0323070424408 ko04924 Renin secretion 4/105 86/7206 0.0363912219605 ko04918 Thyroid hormone synthesis 4/105 86/7206 0.0363912219605 ko04970 Salivary secretion 4/105 95/7206 0.0494706040145