ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	58/501	145/7206	1.889111365e-30
ko04110	Cell cycle	48/501	145/7206	3.97186452061e-21
ko03030	DNA replication	25/501	38/7206	1.47564930695e-20
ko04111	Cell cycle - yeast	37/501	90/7206	3.22217063893e-20
ko03430	Mismatch repair	14/501	22/7206	9.86398287933e-12
ko04113	Meiosis - yeast	23/501	70/7206	1.17465434331e-10
ko03410	Base excision repair	16/501	38/7206	1.25213914625e-09
ko03015	mRNA surveillance pathway	24/501	93/7206	1.11509825076e-08
ko00240	Pyrimidine metabolism	26/501	110/7206	1.99343179034e-08
ko03013	RNA transport	33/501	166/7206	2.52769025654e-08
ko03460	Fanconi anemia pathway	17/501	51/7206	2.54892690774e-08
ko04020	Calcium signaling pathway	1/501	265/7206	1.82142279106e-07
ko03420	Nucleotide excision repair	15/501	46/7206	2.37957349868e-07
ko03440	Homologous recombination	13/501	41/7206	2.19687460689e-06
ko05217	Basal cell carcinoma	17/501	68/7206	2.55297824953e-06
ko03008	Ribosome biogenesis in eukaryotes	18/501	79/7206	5.43890817266e-06
ko04144	Endocytosis	7/501	342/7206	4.57731661807e-05
ko04723	Retrograde endocannabinoid signaling	1/501	175/7206	6.56614031845e-05
ko04371	Apelin signaling pathway	1/501	177/7206	6.6293299039e-05
ko04330	Notch signaling pathway	14/501	62/7206	6.69208374852e-05
ko05166	HTLV-I infection	39/501	292/7206	7.99753183101e-05
ko04910	Insulin signaling pathway	1/501	172/7206	9.89298313857e-05
ko04022	cGMP-PKG signaling pathway	3/501	216/7206	0.000204191969522
ko04725	Cholinergic synapse	1/501	160/7206	0.000213515224072
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/501	182/7206	0.000320626799657
ko04921	Oxytocin signaling pathway	3/501	209/7206	0.000435881954814
ko00230	Purine metabolism	27/501	194/7206	0.000469214882013
ko04072	Phospholipase D signaling pathway	3/501	197/7206	0.000877735807968
ko04713	Circadian entrainment	1/501	136/7206	0.000989760768035
ko04931	Insulin resistance	1/501	137/7206	0.000997231646559
ko04915	Estrogen signaling pathway	1/501	131/7206	0.00145845731038
ko04550	Signaling pathways regulating pluripotency of stem cells	23/501	165/7206	0.00154525771986
ko04024	cAMP signaling pathway	7/501	279/7206	0.00159167293627
ko04261	Adrenergic signaling in cardiomyocytes	4/501	205/7206	0.00192010306413
ko04621	NOD-like receptor signaling pathway	2/501	157/7206	0.00209125068862
ko05224	Breast cancer	23/501	174/7206	0.00235584364531
ko04310	Wnt signaling pathway	24/501	181/7206	0.0025755342559
ko04390	Hippo signaling pathway	24/501	188/7206	0.00330280905224
ko04211	Longevity regulating pathway	1/501	123/7206	0.00333390685753
ko04911	Insulin secretion	1/501	117/7206	0.00483008879297
ko04728	Dopaminergic synapse	4/501	185/7206	0.00512087763768
ko04340	Hedgehog signaling pathway	10/501	58/7206	0.00608503368566
ko04062	Chemokine signaling pathway	5/501	201/7206	0.00721103008913
ko03018	RNA degradation	13/501	84/7206	0.00723073526218
ko05231	Choline metabolism in cancer	2/501	134/7206	0.00875157541517
ko04270	Vascular smooth muscle contraction	3/501	154/7206	0.00941880994347
ko04114	Oocyte meiosis	18/501	139/7206	0.0101684850872
ko04612	Antigen processing and presentation	12/501	77/7206	0.0102273173502
ko04066	HIF-1 signaling pathway	2/501	123/7206	0.0117992634898
ko04922	Glucagon signaling pathway	2/501	128/7206	0.0123823019068
ko04060	Cytokine-cytokine receptor interaction	5/501	191/7206	0.01339441311
ko04974	Protein digestion and absorption	1/501	96/7206	0.0140383458058
ko04650	Natural killer cell mediated cytotoxicity	1/501	97/7206	0.0141571218633
ko00564	Glycerophospholipid metabolism	1/501	99/7206	0.014619538782
ko05206	MicroRNAs in cancer	21/501	177/7206	0.0154495560842
ko04218	Cellular senescence	21/501	177/7206	0.0154495560842
ko00514	Other types of O-glycan biosynthesis	6/501	30/7206	0.0155267493811
ko04120	Ubiquitin mediated proteolysis	17/501	138/7206	0.0175926228655
ko05031	Amphetamine addiction	1/501	91/7206	0.0204962897175
ko05200	Pathways in cancer	47/501	492/7206	0.0217009355539
ko05414	Dilated cardiomyopathy	2/501	112/7206	0.0236111163836
ko04380	Osteoclast differentiation	3/501	134/7206	0.0248908126646
ko05203	Viral carcinogenesis	29/501	277/7206	0.0289660807521
ko04924	Renin secretion	1/501	86/7206	0.0299556759097
ko04350	TGF-beta signaling pathway	13/501	103/7206	0.0305965541276
ko05222	Small cell lung cancer	12/501	89/7206	0.0317978061533
ko04925	Aldosterone synthesis and secretion	2/501	105/7206	0.0332076068862
ko04659	Th17 cell differentiation	2/501	106/7206	0.033228142495
ko01521	EGFR tyrosine kinase inhibitor resistance	2/501	106/7206	0.033228142495
ko04540	Gap junction	3/501	128/7206	0.0343161946116
ko04151	PI3K-Akt signaling pathway	17/501	390/7206	0.039951957965
ko04730	Long-term depression	1/501	78/7206	0.0425240596699
ko04137	Mitophagy - animal	1/501	82/7206	0.0446122302927
ko04720	Long-term potentiation	2/501	99/7206	0.0465736797971
ko05146	Amoebiasis	2/501	99/7206	0.0465736797971
ko05410	Hypertrophic cardiomyopathy (HCM)	2/501	100/7206	0.0466029581308
ko04620	Toll-like receptor signaling pathway	2/501	100/7206	0.0466029581308
ko04912	GnRH signaling pathway	3/501	122/7206	0.0471214218827
ko04750	Inflammatory mediator regulation of TRP channels	3/501	122/7206	0.0471214218827
ko03020	RNA polymerase	5/501	29/7206	0.0472286374054