ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 34/280 191/7206 3.6828431627e-14 ko04650 Natural killer cell mediated cytotoxicity 20/280 97/7206 5.74655358136e-10 ko05340 Primary immunodeficiency 11/280 30/7206 7.09603493444e-09 ko04380 Osteoclast differentiation 22/280 134/7206 7.27428270497e-09 ko05140 Leishmaniasis 15/280 75/7206 1.33327485574e-07 ko05150 Staphylococcus aureus infection 10/280 36/7206 6.93307033079e-07 ko05321 Inflammatory bowel disease (IBD) 12/280 56/7206 1.13095977347e-06 ko04610 Complement and coagulation cascades 14/280 79/7206 1.65656759605e-06 ko05330 Allograft rejection 8/280 24/7206 2.01053416609e-06 ko04659 Th17 cell differentiation 16/280 106/7206 2.7650744517e-06 ko05162 Measles 17/280 120/7206 3.30515553416e-06 ko04640 Hematopoietic cell lineage 12/280 64/7206 5.0351827834e-06 ko04660 T cell receptor signaling pathway 17/280 124/7206 5.22042953677e-06 ko04658 Th1 and Th2 cell differentiation 14/280 96/7206 1.75801186566e-05 ko04064 NF-kappa B signaling pathway 14/280 96/7206 1.75801186566e-05 ko05168 Herpes simplex infection 20/280 182/7206 2.34309574169e-05 ko05145 Toxoplasmosis 16/280 126/7206 2.653480516e-05 ko05152 Tuberculosis 20/280 187/7206 3.48189958493e-05 ko04612 Antigen processing and presentation 12/280 77/7206 3.58617733871e-05 ko05332 Graft-versus-host disease 6/280 18/7206 4.08025183549e-05 ko05144 Malaria 9/280 45/7206 4.59035233099e-05 ko04630 Jak-STAT signaling pathway 16/280 132/7206 4.744333829e-05 ko04672 Intestinal immune network for IgA production 8/280 37/7206 6.79191981022e-05 ko05320 Autoimmune thyroid disease 7/280 29/7206 9.27150100884e-05 ko04145 Phagosome 17/280 162/7206 0.000171119229901 ko05164 Influenza A 17/280 167/7206 0.000247345856163 ko04217 Necroptosis 17/280 178/7206 0.000525117865167 ko04611 Platelet activation 16/280 163/7206 0.000564418653672 ko04062 Chemokine signaling pathway 18/280 201/7206 0.00109223887507 ko04621 NOD-like receptor signaling pathway 15/280 157/7206 0.00110470261917 ko04940 Type I diabetes mellitus 6/280 32/7206 0.00125886773369 ko04620 Toll-like receptor signaling pathway 11/280 100/7206 0.00163729581807 ko05034 Alcoholism 1/280 238/7206 0.00165556908243 ko04662 B cell receptor signaling pathway 10/280 88/7206 0.00206765874996 ko04666 Fc gamma R-mediated phagocytosis 12/280 122/7206 0.00267416730662 ko05310 Asthma 4/280 17/7206 0.00355611417601 ko04514 Cell adhesion molecules (CAMs) 12/280 130/7206 0.00451058419937 ko00120 Primary bile acid biosynthesis 4/280 20/7206 0.00660471325121 ko05323 Rheumatoid arthritis 9/280 89/7206 0.00741673629669 ko04670 Leukocyte transendothelial migration 13/280 151/7206 0.00810467729041 ko04664 Fc epsilon RI signaling pathway 8/280 77/7206 0.00968590170471 ko04310 Wnt signaling pathway 1/280 181/7206 0.010398373857 ko04141 Protein processing in endoplasmic reticulum 1/280 184/7206 0.0105273818793 ko04728 Dopaminergic synapse 1/280 185/7206 0.0106047674831 ko04022 cGMP-PKG signaling pathway 16/280 216/7206 0.0114335159103 ko00590 Arachidonic acid metabolism 6/280 52/7206 0.0148064861889 ko05224 Breast cancer 1/280 174/7206 0.0152621547654 ko04723 Retrograde endocannabinoid signaling 1/280 175/7206 0.0153786209445 ko05142 Chagas disease (American trypanosomiasis) 11/280 130/7206 0.0175874458017 ko03050 Proteasome 6/280 54/7206 0.0176170080888 ko05416 Viral myocarditis 6/280 55/7206 0.0191510229533 ko05133 Pertussis 8/280 87/7206 0.0193208036897 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/280 191/7206 0.0206176248641 ko03013 RNA transport 1/280 166/7206 0.0224639025031 ko04622 RIG-I-like receptor signaling pathway 6/280 62/7206 0.0324824236913 ko04360 Axon guidance 3/280 233/7206 0.0364168382898 ko04137 Mitophagy - animal 7/280 82/7206 0.0395342809167 ko05161 Hepatitis B 12/280 173/7206 0.0445945894091 ko04110 Cell cycle 1/280 145/7206 0.0463077730204