ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 26/304 134/7206 3.79027502948e-11 ko05140 Leishmaniasis 16/304 75/7206 6.07420741449e-08 ko05164 Influenza A 24/304 167/7206 1.08431613164e-07 ko04610 Complement and coagulation cascades 15/304 79/7206 7.89150627832e-07 ko05162 Measles 18/304 120/7206 2.36076068475e-06 ko04668 TNF signaling pathway 18/304 120/7206 2.36076068475e-06 ko04620 Toll-like receptor signaling pathway 16/304 100/7206 3.66583435769e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 23/304 191/7206 4.73850880495e-06 ko04621 NOD-like receptor signaling pathway 20/304 157/7206 8.58668915641e-06 ko05161 Hepatitis B 21/304 173/7206 1.09446218723e-05 ko04060 Cytokine-cytokine receptor interaction 22/304 191/7206 1.57249289081e-05 ko05145 Toxoplasmosis 17/304 126/7206 1.925898541e-05 ko05152 Tuberculosis 21/304 187/7206 3.61251403763e-05 ko04623 Cytosolic DNA-sensing pathway 9/304 41/7206 3.99347696888e-05 ko04660 T cell receptor signaling pathway 16/304 124/7206 5.90623465035e-05 ko05321 Inflammatory bowel disease (IBD) 10/304 56/7206 9.7462637203e-05 ko04137 Mitophagy - animal 12/304 82/7206 0.000149105856509 ko04650 Natural killer cell mediated cytotoxicity 13/304 97/7206 0.000198029362559 ko05160 Hepatitis C 17/304 153/7206 0.000228566806872 ko04662 B cell receptor signaling pathway 12/304 88/7206 0.000294702558829 ko04630 Jak-STAT signaling pathway 15/304 132/7206 0.000416624665448 ko04659 Th17 cell differentiation 13/304 106/7206 0.000480862012986 ko04933 AGE-RAGE signaling pathway in diabetic complications 15/304 135/7206 0.000530693296749 ko04672 Intestinal immune network for IgA production 7/304 37/7206 0.000766570111758 ko05132 Salmonella infection 12/304 98/7206 0.000799709273028 ko05168 Herpes simplex infection 18/304 182/7206 0.000987492448558 ko04622 RIG-I-like receptor signaling pathway 9/304 62/7206 0.00106147733352 ko05340 Primary immunodeficiency 6/304 30/7206 0.00135079158436 ko04664 Fc epsilon RI signaling pathway 10/304 77/7206 0.00137195441634 ko00140 Steroid hormone biosynthesis 7/304 41/7206 0.00144869074209 ko05418 Fluid shear stress and atherosclerosis 17/304 173/7206 0.00148602860777 ko05166 HTLV-I infection 24/304 292/7206 0.00153747215202 ko04217 Necroptosis 17/304 178/7206 0.0017397321712 ko04066 HIF-1 signaling pathway 13/304 123/7206 0.00195307358472 ko04658 Th1 and Th2 cell differentiation 11/304 96/7206 0.00225613877443 ko04064 NF-kappa B signaling pathway 11/304 96/7206 0.00225613877443 ko05215 Prostate cancer 12/304 111/7206 0.00238225854345 ko05133 Pertussis 10/304 87/7206 0.00345289151252 ko05150 Staphylococcus aureus infection 6/304 36/7206 0.00358278042983 ko04611 Platelet activation 15/304 163/7206 0.0043930163932 ko04612 Antigen processing and presentation 9/304 77/7206 0.00486050828111 ko04666 Fc gamma R-mediated phagocytosis 12/304 122/7206 0.00519394174279 ko00590 Arachidonic acid metabolism 7/304 52/7206 0.00580501457247 ko04670 Leukocyte transendothelial migration 14/304 151/7206 0.00589285397229 ko00592 alpha-Linolenic acid metabolism 4/304 19/7206 0.00728160049867 ko05146 Amoebiasis 10/304 99/7206 0.00863235287698 ko00120 Primary bile acid biosynthesis 4/304 20/7206 0.0088050655055 ko04145 Phagosome 14/304 162/7206 0.00917336775283 ko05144 Malaria 6/304 45/7206 0.0109153079371 ko05142 Chagas disease (American trypanosomiasis) 12/304 130/7206 0.0120535424495 ko05323 Rheumatoid arthritis 9/304 89/7206 0.0123499696185 ko04210 Apoptosis 15/304 180/7206 0.0124113957488 ko05010 Alzheimer's disease 2/304 202/7206 0.0125481693791 ko01524 Platinum drug resistance 8/304 76/7206 0.0142746445573 ko05012 Parkinson's disease 1/304 155/7206 0.0229546236184 ko05212 Pancreatic cancer 8/304 83/7206 0.0232173776416 ko00051 Fructose and mannose metabolism 5/304 42/7206 0.0306503954354 ko05310 Asthma 3/304 17/7206 0.0325854074094 ko05169 Epstein-Barr virus infection 15/304 206/7206 0.0338709787008 ko05134 Legionellosis 7/304 74/7206 0.0357475259995 ko04115 p53 signaling pathway 7/304 74/7206 0.0357475259995 ko00190 Oxidative phosphorylation 1/304 127/7206 0.0447431986335 ko01200 Carbon metabolism 1/304 128/7206 0.0447493958439 ko04540 Gap junction 1/304 128/7206 0.0447493958439 ko04215 Apoptosis - multiple species 5/304 47/7206 0.0466932908277 ko05034 Alcoholism 4/304 238/7206 0.0475298915393 ko03013 RNA transport 2/304 166/7206 0.0489030647219