ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 22/277 96/7206 6.61766544358e-12 ko04512 ECM-receptor interaction 20/277 79/7206 8.6361600327e-12 ko05410 Hypertrophic cardiomyopathy (HCM) 17/277 100/7206 2.00231150198e-07 ko04510 Focal adhesion 27/277 240/7206 4.19948586837e-07 ko04260 Cardiac muscle contraction 16/277 98/7206 8.14951116621e-07 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 14/277 79/7206 1.45688546237e-06 ko00643 Styrene degradation 4/277 4/7206 2.13824145881e-06 ko00350 Tyrosine metabolism 9/277 33/7206 2.75497866604e-06 ko05414 Dilated cardiomyopathy 16/277 112/7206 5.03315117335e-06 ko04020 Calcium signaling pathway 23/277 265/7206 0.000227314605008 ko00500 Starch and sucrose metabolism 7/277 35/7206 0.000306175692519 ko00620 Pyruvate metabolism 8/277 46/7206 0.000314928648683 ko04261 Adrenergic signaling in cardiomyocytes 19/277 205/7206 0.000318682541944 ko00360 Phenylalanine metabolism 5/277 17/7206 0.000342302921648 ko00120 Primary bile acid biosynthesis 5/277 20/7206 0.000780013042915 ko00140 Steroid hormone biosynthesis 7/277 41/7206 0.000840354017202 ko00362 Benzoate degradation 3/277 6/7206 0.00103088197194 ko05416 Viral myocarditis 8/277 55/7206 0.00108937907952 ko03320 PPAR signaling pathway 9/277 69/7206 0.00120346444614 ko01200 Carbon metabolism 13/277 128/7206 0.00121788971629 ko00071 Fatty acid degradation 7/277 45/7206 0.00148774194946 ko00010 Glycolysis / Gluconeogenesis 9/277 74/7206 0.00198551511594 ko00380 Tryptophan metabolism 7/277 50/7206 0.00278066105862 ko05146 Amoebiasis 10/277 99/7206 0.00455336516464 ko04022 cGMP-PKG signaling pathway 17/277 216/7206 0.0056874132618 ko04151 PI3K-Akt signaling pathway 26/277 390/7206 0.00609995151624 ko05222 Small cell lung cancer 9/277 89/7206 0.0069272494098 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/277 11/7206 0.00736900810103 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/277 4/7206 0.00839183641546 ko04921 Oxytocin signaling pathway 16/277 209/7206 0.00886298135896 ko00640 Propanoate metabolism 5/277 34/7206 0.00902380987658 ko00053 Ascorbate and aldarate metabolism 4/277 22/7206 0.00903894410876 ko00410 beta-Alanine metabolism 5/277 35/7206 0.0102051075174 ko04152 AMPK signaling pathway 13/277 161/7206 0.0105906398168 ko04672 Intestinal immune network for IgA production 5/277 37/7206 0.012877006495 ko00281 Geraniol degradation 2/277 5/7206 0.0136327137092 ko00280 Valine, leucine and isoleucine degradation 6/277 54/7206 0.0167888202758 ko00710 Carbon fixation in photosynthetic organisms 4/277 27/7206 0.0186659337725 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/277 135/7206 0.0193593193762 ko00310 Lysine degradation 7/277 73/7206 0.0215217041685 ko01212 Fatty acid metabolism 6/277 60/7206 0.0269211187962 ko04614 Renin-angiotensin system 3/277 18/7206 0.0298885837391 ko05322 Systemic lupus erythematosus 1/277 151/7206 0.0312958295334 ko00561 Glycerolipid metabolism 6/277 63/7206 0.0332437322926 ko04976 Bile secretion 7/277 80/7206 0.0335215773758 ko00260 Glycine, serine and threonine metabolism 5/277 48/7206 0.0360247104809 ko05203 Viral carcinogenesis 4/277 277/7206 0.0360456736604 ko00401 Novobiocin biosynthesis 1/277 1/7206 0.0384401887318 ko00680 Methane metabolism 4/277 34/7206 0.0400577537591 ko00020 Citrate cycle (TCA cycle) 4/277 35/7206 0.0439097081125 ko00627 Aminobenzoate degradation 2/277 9/7206 0.0443359028214 ko01230 Biosynthesis of amino acids 7/277 85/7206 0.0443989139493 ko00100 Steroid biosynthesis 3/277 21/7206 0.0447866852317 ko04114 Oocyte meiosis 1/277 139/7206 0.0449838964439 ko03040 Spliceosome 1/277 145/7206 0.0457672869502 ko04110 Cell cycle 1/277 145/7206 0.0457672869502