ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	108/580	423/7206	1.06910361577e-29
ko05033	Nicotine addiction	37/580	56/7206	1.09212242664e-27
ko04724	Glutamatergic synapse	58/580	152/7206	1.00892620062e-25
ko04721	Synaptic vesicle cycle	37/580	80/7206	3.50443601219e-20
ko04727	GABAergic synapse	43/580	110/7206	8.80309422133e-20
ko05032	Morphine addiction	42/580	110/7206	6.82551570226e-19
ko04723	Retrograde endocannabinoid signaling	52/580	175/7206	1.48641025703e-17
ko04728	Dopaminergic synapse	53/580	185/7206	4.20862031137e-17
ko04713	Circadian entrainment	42/580	136/7206	4.87810146805e-15
ko04726	Serotonergic synapse	37/580	137/7206	1.97136608119e-11
ko04725	Cholinergic synapse	40/580	160/7206	4.12808171144e-11
ko04024	cAMP signaling pathway	55/580	279/7206	2.46979361428e-10
ko04744	Phototransduction	17/580	36/7206	4.01725036441e-10
ko04742	Taste transduction	21/580	61/7206	4.17138292686e-09
ko04911	Insulin secretion	29/580	117/7206	2.59799743475e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	22/580	74/7206	3.84937261001e-08
ko05031	Amphetamine addiction	24/580	91/7206	1.18892673811e-07
ko05030	Cocaine addiction	21/580	73/7206	1.47616853027e-07
ko04261	Adrenergic signaling in cardiomyocytes	38/580	205/7206	1.26404532879e-06
ko04720	Long-term potentiation	22/580	99/7206	8.82410760469e-06
ko04514	Cell adhesion molecules (CAMs)	26/580	130/7206	1.06537986138e-05
ko04921	Oxytocin signaling pathway	36/580	209/7206	1.22625462935e-05
ko04970	Salivary secretion	21/580	95/7206	1.53615656252e-05
ko05205	Proteoglycans in cancer	5/580	271/7206	1.78800525077e-05
ko05164	Influenza A	1/580	167/7206	1.88281984003e-05
ko04010	MAPK signaling pathway	48/580	321/7206	2.09575890515e-05
ko04060	Cytokine-cytokine receptor interaction	2/580	191/7206	3.36568909117e-05
ko04730	Long-term depression	17/580	78/7206	0.000118832819229
ko04966	Collecting duct acid secretion	9/580	26/7206	0.000119591847423
ko03040	Spliceosome	1/580	145/7206	0.00014106511546
ko05203	Viral carcinogenesis	7/580	277/7206	0.000166186608953
ko04120	Ubiquitin mediated proteolysis	1/580	138/7206	0.000199923305171
ko04972	Pancreatic secretion	20/580	111/7206	0.000559789026672
ko05322	Systemic lupus erythematosus	2/580	151/7206	0.000671847585117
ko04260	Cardiac muscle contraction	18/580	98/7206	0.000964775889786
ko05162	Measles	1/580	120/7206	0.000974804172617
ko05168	Herpes simplex infection	4/580	182/7206	0.00131477359607
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/580	182/7206	0.00131477359607
ko04022	cGMP-PKG signaling pathway	31/580	216/7206	0.00134796831571
ko04020	Calcium signaling pathway	36/580	265/7206	0.00171120996861
ko05034	Alcoholism	33/580	238/7206	0.00217268879145
ko03013	RNA transport	4/580	166/7206	0.00356581801097
ko05169	Epstein-Barr virus infection	6/580	206/7206	0.00384242865327
ko05166	HTLV-I infection	11/580	292/7206	0.00406910877949
ko05146	Amoebiasis	1/580	99/7206	0.00441195784468
ko04540	Gap junction	20/580	128/7206	0.00442938849198
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/580	79/7206	0.00507809837221
ko04140	Autophagy - animal	4/580	164/7206	0.00512688717476
ko04964	Proximal tubule bicarbonate reclamation	7/580	29/7206	0.00688773398539
ko04621	NOD-like receptor signaling pathway	4/580	157/7206	0.00691391754994
ko04971	Gastric acid secretion	16/580	98/7206	0.00723852862535
ko04146	Peroxisome	1/580	89/7206	0.00941491401225
ko04360	Axon guidance	30/580	233/7206	0.0095979182393
ko04740	Olfactory transduction	13/580	80/7206	0.0120318314829
ko05016	Huntington's disease	8/580	215/7206	0.0149769274148
ko05110	Vibrio cholerae infection	11/580	63/7206	0.0158779107675
ko04350	TGF-beta signaling pathway	2/580	103/7206	0.0163252932696
ko05120	Epithelial cell signaling in Helicobacter pylori infection	14/580	92/7206	0.0185596080809
ko04612	Antigen processing and presentation	1/580	77/7206	0.0196910499317
ko03008	Ribosome biogenesis in eukaryotes	1/580	79/7206	0.0199699817435
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/580	14/7206	0.0216707168301
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/580	59/7206	0.0251223772435
ko04071	Sphingolipid signaling pathway	21/580	162/7206	0.0273232817767
ko04925	Aldosterone synthesis and secretion	15/580	105/7206	0.0277600192549
ko04141	Protein processing in endoplasmic reticulum	7/580	184/7206	0.0277637483695
ko04214	Apoptosis - fly	1/580	72/7206	0.0285954096951
ko01524	Platinum drug resistance	1/580	76/7206	0.0301850004709
ko01200	Carbon metabolism	4/580	128/7206	0.0330036981902
ko00240	Pyrimidine metabolism	3/580	110/7206	0.0334489314686
ko04976	Bile secretion	12/580	80/7206	0.0348441432488
ko04217	Necroptosis	7/580	178/7206	0.0364262287762
ko04978	Mineral absorption	7/580	40/7206	0.0382767768853
ko04014	Ras signaling pathway	32/580	279/7206	0.0422690245321
ko04110	Cell cycle	5/580	145/7206	0.0430107044781
ko04066	HIF-1 signaling pathway	4/580	123/7206	0.0446577110225
ko04072	Phospholipase D signaling pathway	24/580	197/7206	0.0446896128085
ko05161	Hepatitis B	7/580	173/7206	0.0475322994803
ko04062	Chemokine signaling pathway	24/580	201/7206	0.0475816329107
ko04915	Estrogen signaling pathway	17/580	131/7206	0.0493449246643