ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	179/1030	423/7206	3.18586180488e-48
ko04724	Glutamatergic synapse	82/1030	152/7206	3.49074628502e-31
ko05033	Nicotine addiction	46/1030	56/7206	4.78730517014e-30
ko05032	Morphine addiction	63/1030	110/7206	4.1316415497e-26
ko04727	GABAergic synapse	61/1030	110/7206	2.7757727691e-24
ko04713	Circadian entrainment	67/1030	136/7206	1.13246504686e-22
ko04728	Dopaminergic synapse	78/1030	185/7206	6.97196468586e-21
ko04723	Retrograde endocannabinoid signaling	73/1030	175/7206	2.76577758916e-19
ko04725	Cholinergic synapse	68/1030	160/7206	1.47054294369e-18
ko04721	Synaptic vesicle cycle	45/1030	80/7206	1.51822514234e-18
ko04024	cAMP signaling pathway	95/1030	279/7206	2.02740545184e-17
ko04020	Calcium signaling pathway	89/1030	265/7206	5.20515097934e-16
ko04742	Taste transduction	34/1030	61/7206	3.70428528054e-14
ko04726	Serotonergic synapse	55/1030	137/7206	5.84790350046e-14
ko04911	Insulin secretion	49/1030	117/7206	2.08725391746e-13
ko04921	Oxytocin signaling pathway	68/1030	209/7206	1.28846253237e-11
ko04261	Adrenergic signaling in cardiomyocytes	65/1030	205/7206	9.84826686532e-11
ko05031	Amphetamine addiction	37/1030	91/7206	5.33026172589e-10
ko04744	Phototransduction	21/1030	36/7206	9.79697162754e-10
ko04720	Long-term potentiation	38/1030	99/7206	2.21207939326e-09
ko04970	Salivary secretion	37/1030	95/7206	2.24070649832e-09
ko03040	Spliceosome	1/1030	145/7206	5.73146137507e-09
ko05203	Viral carcinogenesis	12/1030	277/7206	6.18179318744e-08
ko04971	Gastric acid secretion	33/1030	98/7206	1.15482166486e-06
ko04060	Cytokine-cytokine receptor interaction	7/1030	191/7206	1.65114194129e-06
ko04925	Aldosterone synthesis and secretion	34/1030	105/7206	1.81684622716e-06
ko04022	cGMP-PKG signaling pathway	57/1030	216/7206	2.40315282512e-06
ko04360	Axon guidance	60/1030	233/7206	2.46136519975e-06
ko04740	Olfactory transduction	28/1030	80/7206	2.56203312676e-06
ko05322	Systemic lupus erythematosus	4/1030	151/7206	2.70172717087e-06
ko05030	Cocaine addiction	26/1030	73/7206	4.01805855927e-06
ko05168	Herpes simplex infection	7/1030	182/7206	4.8184629055e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1030	74/7206	5.36622565843e-06
ko05164	Influenza A	6/1030	167/7206	8.77920860497e-06
ko04010	MAPK signaling pathway	75/1030	321/7206	8.79678990037e-06
ko04514	Cell adhesion molecules (CAMs)	38/1030	130/7206	1.03037049106e-05
ko04070	Phosphatidylinositol signaling system	34/1030	112/7206	1.40752436287e-05
ko04621	NOD-like receptor signaling pathway	6/1030	157/7206	2.48626236443e-05
ko04014	Ras signaling pathway	65/1030	279/7206	3.67335555475e-05
ko03013	RNA transport	7/1030	166/7206	4.05473375665e-05
ko04972	Pancreatic secretion	32/1030	111/7206	5.60036206605e-05
ko04120	Ubiquitin mediated proteolysis	5/1030	138/7206	6.35119466417e-05
ko04072	Phospholipase D signaling pathway	49/1030	197/7206	7.11571687579e-05
ko04966	Collecting duct acid secretion	12/1030	26/7206	9.47407666251e-05
ko04745	Phototransduction - fly	15/1030	38/7206	0.00011744560539
ko04141	Protein processing in endoplasmic reticulum	10/1030	184/7206	0.000165215374597
ko04612	Antigen processing and presentation	1/1030	77/7206	0.000204010308535
ko04730	Long-term depression	24/1030	78/7206	0.000220382807182
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/1030	79/7206	0.000244602821309
ko04924	Renin secretion	25/1030	86/7206	0.000471882704886
ko04064	NF-kappa B signaling pathway	3/1030	96/7206	0.000575564736669
ko05161	Hepatitis B	10/1030	173/7206	0.00057707977843
ko04260	Cardiac muscle contraction	27/1030	98/7206	0.000642055325061
ko03008	Ribosome biogenesis in eukaryotes	2/1030	79/7206	0.000960021722078
ko05414	Dilated cardiomyopathy	29/1030	112/7206	0.000982589947959
ko04110	Cell cycle	8/1030	145/7206	0.00110409339618
ko04540	Gap junction	32/1030	128/7206	0.00124768093769
ko05140	Leishmaniasis	2/1030	75/7206	0.00137996402279
ko05162	Measles	6/1030	120/7206	0.00217028265316
ko05169	Epstein-Barr virus infection	15/1030	206/7206	0.00232291075658
ko05205	Proteoglycans in cancer	22/1030	271/7206	0.00249077939088
ko05110	Vibrio cholerae infection	18/1030	63/7206	0.00306242619929
ko00480	Glutathione metabolism	1/1030	55/7206	0.00326873605764
ko00562	Inositol phosphate metabolism	23/1030	89/7206	0.00344770869543
ko05166	HTLV-I infection	25/1030	292/7206	0.00355556358182
ko04371	Apelin signaling pathway	39/1030	177/7206	0.00451964377766
ko04217	Necroptosis	13/1030	178/7206	0.00472418351138
ko04964	Proximal tubule bicarbonate reclamation	10/1030	29/7206	0.00515676480241
ko04610	Complement and coagulation cascades	3/1030	79/7206	0.00517590921558
ko04146	Peroxisome	4/1030	89/7206	0.00542748015055
ko04976	Bile secretion	21/1030	80/7206	0.00542942868163
ko00240	Pyrimidine metabolism	6/1030	110/7206	0.00552405601216
ko04750	Inflammatory mediator regulation of TRP channels	29/1030	122/7206	0.00559236739743
ko04915	Estrogen signaling pathway	30/1030	131/7206	0.00763058447131
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/1030	59/7206	0.00828509273943
ko04626	Plant-pathogen interaction	7/1030	18/7206	0.00900845530819
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1030	14/7206	0.00904166862369
ko00330	Arginine and proline metabolism	2/1030	61/7206	0.00911268411029
ko04930	Type II diabetes mellitus	15/1030	54/7206	0.00947137642544
ko03420	Nucleotide excision repair	1/1030	46/7206	0.0108344726963
ko04510	Focal adhesion	21/1030	240/7206	0.0110806158479
ko05219	Bladder cancer	1/1030	48/7206	0.0111363666183
ko05215	Prostate cancer	7/1030	111/7206	0.0131898154011
ko04923	Regulation of lipolysis in adipocytes	19/1030	77/7206	0.0133952850754
ko03022	Basal transcription factors	1/1030	44/7206	0.0160789266956
ko05144	Malaria	1/1030	45/7206	0.0164526223908
ko00071	Fatty acid degradation	1/1030	45/7206	0.0164526223908
ko04140	Autophagy - animal	13/1030	164/7206	0.0172600875486
ko04015	Rap1 signaling pathway	54/1030	278/7206	0.0178855992077
ko04658	Th1 and Th2 cell differentiation	6/1030	96/7206	0.018731699359
ko04657	IL-17 signaling pathway	5/1030	87/7206	0.0197639646409
ko05410	Hypertrophic cardiomyopathy (HCM)	23/1030	100/7206	0.0200392036753
ko04630	Jak-STAT signaling pathway	10/1030	132/7206	0.02350772752
ko04214	Apoptosis - fly	4/1030	72/7206	0.0279098747164
ko00310	Lysine degradation	4/1030	73/7206	0.0279215351365
ko04330	Notch signaling pathway	3/1030	62/7206	0.0281963118244
ko04622	RIG-I-like receptor signaling pathway	3/1030	62/7206	0.0281963118244
ko04115	p53 signaling pathway	4/1030	74/7206	0.0282931568589
ko04922	Glucagon signaling pathway	27/1030	128/7206	0.0304551043706
ko04932	Non-alcoholic fatty liver disease (NAFLD)	16/1030	182/7206	0.0314611607934
ko05231	Choline metabolism in cancer	28/1030	134/7206	0.0336088989066
ko00260	Glycine, serine and threonine metabolism	2/1030	48/7206	0.0389449381935
ko05145	Toxoplasmosis	10/1030	126/7206	0.039393366146
ko04210	Apoptosis	16/1030	180/7206	0.0396256214776
ko05133	Pertussis	6/1030	87/7206	0.0451448447275
ko04142	Lysosome	13/1030	151/7206	0.0451640801422
ko05222	Small cell lung cancer	6/1030	89/7206	0.0458266834424
ko04710	Circadian rhythm	11/1030	43/7206	0.0461777598041
ko00680	Methane metabolism	9/1030	34/7206	0.0499918923269