ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	137/887	423/7206	2.04624787672e-29
ko05033	Nicotine addiction	42/887	56/7206	2.70743914172e-27
ko04724	Glutamatergic synapse	72/887	152/7206	4.65062458624e-27
ko04727	GABAergic synapse	53/887	110/7206	1.32700428106e-20
ko05032	Morphine addiction	53/887	110/7206	1.32700428106e-20
ko04721	Synaptic vesicle cycle	44/887	80/7206	3.17581249514e-20
ko04728	Dopaminergic synapse	67/887	185/7206	1.80031727217e-17
ko04713	Circadian entrainment	54/887	136/7206	2.66441897528e-16
ko04723	Retrograde endocannabinoid signaling	62/887	175/7206	1.02158643822e-15
ko04744	Phototransduction	25/887	36/7206	2.08263058998e-15
ko04725	Cholinergic synapse	57/887	160/7206	1.15997830439e-14
ko04742	Taste transduction	28/887	61/7206	7.69661264605e-11
ko04024	cAMP signaling pathway	72/887	279/7206	3.19609937567e-10
ko04911	Insulin secretion	40/887	117/7206	4.8904327485e-10
ko04726	Serotonergic synapse	43/887	137/7206	2.29123031656e-09
ko05203	Viral carcinogenesis	8/887	277/7206	3.43996240414e-08
ko03040	Spliceosome	1/887	145/7206	1.43558464334e-07
ko05030	Cocaine addiction	26/887	73/7206	2.17206612283e-07
ko04921	Oxytocin signaling pathway	52/887	209/7206	4.97129299767e-07
ko04261	Adrenergic signaling in cardiomyocytes	51/887	205/7206	6.96614586285e-07
ko05164	Influenza A	3/887	167/7206	1.05365884107e-06
ko05031	Amphetamine addiction	28/887	91/7206	2.28287921131e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/887	74/7206	4.3250897596e-06
ko04060	Cytokine-cytokine receptor interaction	6/887	191/7206	1.02699942063e-05
ko05205	Proteoglycans in cancer	12/887	271/7206	1.14358423233e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/887	79/7206	1.52554004094e-05
ko05168	Herpes simplex infection	6/887	182/7206	2.95937519522e-05
ko04120	Ubiquitin mediated proteolysis	3/887	138/7206	3.37106589287e-05
ko04260	Cardiac muscle contraction	27/887	98/7206	3.52429273243e-05
ko03013	RNA transport	5/887	166/7206	3.62600261492e-05
ko04010	MAPK signaling pathway	65/887	321/7206	3.74047159658e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/887	14/7206	7.74564316954e-05
ko04740	Olfactory transduction	23/887	80/7206	8.61151528966e-05
ko04621	NOD-like receptor signaling pathway	5/887	157/7206	0.000107282512425
ko04514	Cell adhesion molecules (CAMs)	32/887	130/7206	0.000114052579791
ko04966	Collecting duct acid secretion	11/887	26/7206	0.000123182761515
ko04720	Long-term potentiation	26/887	99/7206	0.00014136164282
ko05322	Systemic lupus erythematosus	5/887	151/7206	0.000148312543984
ko04020	Calcium signaling pathway	54/887	265/7206	0.00017553954219
ko04970	Salivary secretion	25/887	95/7206	0.000194450343876
ko04360	Axon guidance	48/887	233/7206	0.000238964448698
ko05166	HTLV-I infection	17/887	292/7206	0.000251201762081
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/887	182/7206	0.000351205627428
ko04972	Pancreatic secretion	27/887	111/7206	0.000383286425396
ko03008	Ribosome biogenesis in eukaryotes	1/887	79/7206	0.000771901033941
ko04141	Protein processing in endoplasmic reticulum	9/887	184/7206	0.000892914304831
ko05161	Hepatitis B	8/887	173/7206	0.000914857552479
ko05162	Measles	4/887	120/7206	0.00107134720635
ko05169	Epstein-Barr virus infection	11/887	206/7206	0.00113005800517
ko04730	Long-term depression	20/887	78/7206	0.00133122534024
ko04976	Bile secretion	20/887	80/7206	0.00161932971137
ko04964	Proximal tubule bicarbonate reclamation	10/887	29/7206	0.00167921630086
ko04064	NF-kappa B signaling pathway	3/887	96/7206	0.00268315238773
ko04640	Hematopoietic cell lineage	1/887	64/7206	0.00360621075477
ko04217	Necroptosis	10/887	178/7206	0.00372572473483
ko04146	Peroxisome	3/887	89/7206	0.00542643905213
ko00561	Glycerolipid metabolism	1/887	63/7206	0.00567443041816
ko05016	Huntington's disease	14/887	215/7206	0.00606282361142
ko05140	Leishmaniasis	2/887	75/7206	0.00697452643217
ko04022	cGMP-PKG signaling pathway	40/887	216/7206	0.00814451955562
ko04110	Cell cycle	8/887	145/7206	0.0100265582719
ko05110	Vibrio cholerae infection	15/887	63/7206	0.0105801012707
ko03018	RNA degradation	3/887	84/7206	0.0110509727185
ko04140	Autophagy - animal	10/887	164/7206	0.0112809478631
ko00280	Valine, leucine and isoleucine degradation	1/887	54/7206	0.0116704617005
ko00480	Glutathione metabolism	1/887	55/7206	0.0118119927523
ko05414	Dilated cardiomyopathy	23/887	112/7206	0.0127453596881
ko05418	Fluid shear stress and atherosclerosis	11/887	173/7206	0.0134821999764
ko01200	Carbon metabolism	7/887	128/7206	0.0140643040407
ko00590	Arachidonic acid metabolism	1/887	52/7206	0.0175455148809
ko05145	Toxoplasmosis	7/887	126/7206	0.0190178853194
ko04971	Gastric acid secretion	20/887	98/7206	0.0195052811683
ko04924	Renin secretion	18/887	86/7206	0.0200616733115
ko04218	Cellular senescence	12/887	177/7206	0.0203032280589
ko01524	Platinum drug resistance	3/887	76/7206	0.021455216389
ko04612	Antigen processing and presentation	3/887	77/7206	0.0217287272692
ko04630	Jak-STAT signaling pathway	8/887	132/7206	0.0229923467501
ko04925	Aldosterone synthesis and secretion	21/887	105/7206	0.023437323444
ko04668	TNF signaling pathway	7/887	120/7206	0.0249162785666
ko04014	Ras signaling pathway	47/887	279/7206	0.0251592221807
ko05219	Bladder cancer	1/887	48/7206	0.0254693711148
ko00240	Pyrimidine metabolism	6/887	110/7206	0.0270210240147
ko05215	Prostate cancer	6/887	111/7206	0.0274494068759
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/887	59/7206	0.0287326375305
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/887	15/7206	0.0291222731531
ko00330	Arginine and proline metabolism	2/887	61/7206	0.0291912055282
ko00564	Glycerophospholipid metabolism	5/887	99/7206	0.029260911548
ko04214	Apoptosis - fly	3/887	72/7206	0.0299061096798
ko05410	Hypertrophic cardiomyopathy (HCM)	20/887	100/7206	0.0300196856257
ko00310	Lysine degradation	3/887	73/7206	0.0300976987969
ko04657	IL-17 signaling pathway	4/887	87/7206	0.0306978126429
ko05133	Pertussis	4/887	87/7206	0.0306978126429
ko04670	Leukocyte transendothelial migration	10/887	151/7206	0.0323878960731
ko04930	Type II diabetes mellitus	12/887	54/7206	0.035563971991
ko03022	Basal transcription factors	1/887	44/7206	0.0371841140547
ko00071	Fatty acid degradation	1/887	45/7206	0.0376158915551
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/887	92/7206	0.0381172807727
ko00620	Pyruvate metabolism	1/887	46/7206	0.0386447667819
ko03420	Nucleotide excision repair	1/887	46/7206	0.0386447667819
ko05321	Inflammatory bowel disease (IBD)	2/887	56/7206	0.0410374304805
ko03320	PPAR signaling pathway	3/887	69/7206	0.0416735627977