ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	198/1286	423/7206	8.24580490835e-46
ko04724	Glutamatergic synapse	88/1286	152/7206	5.15236163286e-29
ko05033	Nicotine addiction	46/1286	56/7206	1.05852449612e-25
ko04713	Circadian entrainment	74/1286	136/7206	2.72706451399e-22
ko05032	Morphine addiction	64/1286	110/7206	1.55660003557e-21
ko04727	GABAergic synapse	62/1286	110/7206	6.49832732683e-20
ko04020	Calcium signaling pathway	109/1286	265/7206	1.38441654358e-19
ko04728	Dopaminergic synapse	85/1286	185/7206	3.92899116053e-19
ko04725	Cholinergic synapse	77/1286	160/7206	6.59236347594e-19
ko04024	cAMP signaling pathway	106/1286	279/7206	3.99276358805e-16
ko04721	Synaptic vesicle cycle	46/1286	80/7206	1.51277498942e-15
ko04911	Insulin secretion	58/1286	117/7206	2.87023258771e-15
ko04723	Retrograde endocannabinoid signaling	75/1286	175/7206	6.42966012516e-15
ko04921	Oxytocin signaling pathway	83/1286	209/7206	5.13357138246e-14
ko04726	Serotonergic synapse	62/1286	137/7206	6.84283944607e-14
ko04742	Taste transduction	34/1286	61/7206	2.60774422422e-11
ko05031	Amphetamine addiction	43/1286	91/7206	8.77867658226e-11
ko03010	Ribosome	1/1286	129/7206	3.41120219115e-10
ko04970	Salivary secretion	43/1286	95/7206	4.90880902269e-10
ko04720	Long-term potentiation	43/1286	99/7206	2.3926706491e-09
ko04261	Adrenergic signaling in cardiomyocytes	71/1286	205/7206	4.80243171193e-09
ko04925	Aldosterone synthesis and secretion	44/1286	105/7206	6.96681544393e-09
ko05322	Systemic lupus erythematosus	4/1286	151/7206	9.248544268e-09
ko04971	Gastric acid secretion	42/1286	98/7206	9.7096730761e-09
ko03040	Spliceosome	4/1286	145/7206	3.27463556912e-08
ko04744	Phototransduction	21/1286	36/7206	5.94112247824e-08
ko04022	cGMP-PKG signaling pathway	71/1286	216/7206	6.19434918962e-08
ko03013	RNA transport	7/1286	166/7206	1.65690259553e-07
ko05203	Viral carcinogenesis	20/1286	277/7206	3.41265179246e-07
ko04976	Bile secretion	33/1286	80/7206	8.790299349e-07
ko05168	Herpes simplex infection	10/1286	182/7206	1.07266187071e-06
ko04972	Pancreatic secretion	40/1286	111/7206	4.07114406763e-06
ko05030	Cocaine addiction	29/1286	73/7206	9.00908627476e-06
ko04110	Cell cycle	8/1286	145/7206	1.52013649851e-05
ko04070	Phosphatidylinositol signaling system	39/1286	112/7206	1.52682634545e-05
ko04730	Long-term depression	30/1286	78/7206	1.63768208727e-05
ko04360	Axon guidance	68/1286	233/7206	1.67144344337e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	29/1286	74/7206	1.92461250724e-05
ko04740	Olfactory transduction	30/1286	80/7206	2.52512561928e-05
ko04745	Phototransduction - fly	18/1286	38/7206	2.69814432946e-05
ko04270	Vascular smooth muscle contraction	48/1286	154/7206	4.40981652692e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1286	79/7206	4.45706973441e-05
ko05164	Influenza A	12/1286	167/7206	8.8577788109e-05
ko04072	Phospholipase D signaling pathway	57/1286	197/7206	9.78716573049e-05
ko04514	Cell adhesion molecules (CAMs)	41/1286	130/7206	0.000117133000043
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1286	79/7206	0.000161803248853
ko04924	Renin secretion	30/1286	86/7206	0.000161900982947
ko04120	Ubiquitin mediated proteolysis	9/1286	138/7206	0.000175199192537
ko04966	Collecting duct acid secretion	13/1286	26/7206	0.000181269139195
ko04710	Circadian rhythm	18/1286	43/7206	0.000198338464235
ko04060	Cytokine-cytokine receptor interaction	16/1286	191/7206	0.000246397261709
ko04750	Inflammatory mediator regulation of TRP channels	38/1286	122/7206	0.000296437960589
ko04010	MAPK signaling pathway	82/1286	321/7206	0.00043041512276
ko00520	Amino sugar and nucleotide sugar metabolism	1/1286	55/7206	0.000533918352089
ko05140	Leishmaniasis	3/1286	75/7206	0.000661019004884
ko04014	Ras signaling pathway	72/1286	279/7206	0.000760982753416
ko04922	Glucagon signaling pathway	38/1286	128/7206	0.000976059104404
ko04540	Gap junction	38/1286	128/7206	0.000976059104404
ko04621	NOD-like receptor signaling pathway	13/1286	157/7206	0.000980843267767
ko04141	Protein processing in endoplasmic reticulum	17/1286	184/7206	0.00122233114294
ko05110	Vibrio cholerae infection	22/1286	63/7206	0.00129123045453
ko05166	HTLV-I infection	32/1286	292/7206	0.00131441068262
ko05161	Hepatitis B	16/1286	173/7206	0.00175872766041
ko04371	Apelin signaling pathway	48/1286	177/7206	0.00193803905645
ko05414	Dilated cardiomyopathy	33/1286	112/7206	0.00254459009492
ko04964	Proximal tubule bicarbonate reclamation	12/1286	29/7206	0.002577816379
ko03022	Basal transcription factors	1/1286	44/7206	0.00271098965653
ko03420	Nucleotide excision repair	1/1286	46/7206	0.00287610254891
ko05169	Epstein-Barr virus infection	21/1286	206/7206	0.00297320232549
ko04915	Estrogen signaling pathway	37/1286	131/7206	0.00367287525412
ko04622	RIG-I-like receptor signaling pathway	3/1286	62/7206	0.00416918682937
ko04657	IL-17 signaling pathway	6/1286	87/7206	0.00460915990449
ko05133	Pertussis	6/1286	87/7206	0.00460915990449
ko05162	Measles	10/1286	120/7206	0.00526513875134
ko04217	Necroptosis	18/1286	178/7206	0.00528829514812
ko05410	Hypertrophic cardiomyopathy (HCM)	29/1286	100/7206	0.00542459488567
ko04930	Type II diabetes mellitus	18/1286	54/7206	0.00632053099271
ko04612	Antigen processing and presentation	5/1286	77/7206	0.00650212431648
ko04260	Cardiac muscle contraction	28/1286	98/7206	0.00765187629451
ko05219	Bladder cancer	2/1286	48/7206	0.00778614576831
ko04626	Plant-pathogen interaction	8/1286	18/7206	0.00810067090279
ko05131	Shigellosis	6/1286	82/7206	0.0087924500237
ko00630	Glyoxylate and dicarboxylate metabolism	1/1286	38/7206	0.0093907615054
ko03410	Base excision repair	1/1286	38/7206	0.0093907615054
ko04658	Th1 and Th2 cell differentiation	8/1286	96/7206	0.0107063938867
ko04064	NF-kappa B signaling pathway	8/1286	96/7206	0.0107063938867
ko05205	Proteoglycans in cancer	33/1286	271/7206	0.0120129945648
ko05321	Inflammatory bowel disease (IBD)	3/1286	56/7206	0.012745272229
ko04932	Non-alcoholic fatty liver disease (NAFLD)	20/1286	182/7206	0.0138608888838
ko04973	Carbohydrate digestion and absorption	14/1286	42/7206	0.0139678616936
ko04630	Jak-STAT signaling pathway	13/1286	132/7206	0.0153673750509
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/1286	59/7206	0.0159305314045
ko04610	Complement and coagulation cascades	6/1286	79/7206	0.0169147548286
ko05144	Malaria	2/1286	45/7206	0.0170979163592
ko04711	Circadian rhythm - fly	6/1286	13/7206	0.0175111720753
ko00280	Valine, leucine and isoleucine degradation	3/1286	54/7206	0.0185002059368
ko02010	ABC transporters	13/1286	39/7206	0.0188626586888
ko03015	mRNA surveillance pathway	8/1286	93/7206	0.0194946748521
ko03018	RNA degradation	7/1286	84/7206	0.0209561188341
ko04923	Regulation of lipolysis in adipocytes	22/1286	77/7206	0.0233519960232
ko05016	Huntington's disease	26/1286	215/7206	0.023703611097
ko04146	Peroxisome	8/1286	89/7206	0.0255329077418
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1286	14/7206	0.026106024357
ko04214	Apoptosis - fly	6/1286	72/7206	0.0304467079078
ko00310	Lysine degradation	6/1286	73/7206	0.0305117090746
ko04115	p53 signaling pathway	6/1286	74/7206	0.0310775417932
ko05340	Primary immunodeficiency	1/1286	30/7206	0.0316146882222
ko04912	GnRH signaling pathway	31/1286	122/7206	0.0318118683998
ko04916	Melanogenesis	35/1286	142/7206	0.0356808582982
ko04962	Vasopressin-regulated water reabsorption	17/1286	58/7206	0.036488198871
ko04960	Aldosterone-regulated sodium reabsorption	13/1286	41/7206	0.0374091660224
ko04113	Meiosis - yeast	6/1286	70/7206	0.0410014470857
ko05202	Transcriptional misregulation in cancer	23/1286	188/7206	0.0424396706721
ko05012	Parkinson's disease	18/1286	155/7206	0.0433235488195
ko04330	Notch signaling pathway	5/1286	62/7206	0.0446625944203
ko04620	Toll-like receptor signaling pathway	10/1286	100/7206	0.0471638195253
ko05416	Viral myocarditis	4/1286	55/7206	0.0492924064104