ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	132/931	423/7206	2.33418212669e-24
ko04724	Glutamatergic synapse	70/931	152/7206	4.06577928641e-24
ko05033	Nicotine addiction	36/931	56/7206	3.27881418725e-19
ko04728	Dopaminergic synapse	65/931	185/7206	3.68357727025e-15
ko05032	Morphine addiction	47/931	110/7206	5.47706722936e-15
ko04713	Circadian entrainment	53/931	136/7206	1.03961079105e-14
ko04725	Cholinergic synapse	58/931	160/7206	2.45981983177e-14
ko04727	GABAergic synapse	46/931	110/7206	2.84812831933e-14
ko04723	Retrograde endocannabinoid signaling	61/931	175/7206	4.07766741862e-14
ko04721	Synaptic vesicle cycle	37/931	80/7206	2.27855116604e-13
ko04020	Calcium signaling pathway	74/931	265/7206	3.33020045034e-11
ko04726	Serotonergic synapse	47/931	137/7206	6.9909660949e-11
ko04024	cAMP signaling pathway	75/931	279/7206	2.13319486141e-10
ko04911	Insulin secretion	41/931	117/7206	5.59730604107e-10
ko04921	Oxytocin signaling pathway	58/931	209/7206	6.23148311426e-09
ko04070	Phosphatidylinositol signaling system	37/931	112/7206	2.42270212169e-08
ko03040	Spliceosome	1/931	145/7206	5.75066871943e-08
ko04261	Adrenergic signaling in cardiomyocytes	54/931	205/7206	1.35492150988e-07
ko04720	Long-term potentiation	32/931	99/7206	3.77385727278e-07
ko03010	Ribosome	1/931	129/7206	4.60424074365e-07
ko04514	Cell adhesion molecules (CAMs)	38/931	130/7206	8.43531144714e-07
ko04360	Axon guidance	57/931	233/7206	1.22599203719e-06
ko05031	Amphetamine addiction	29/931	91/7206	1.83832540359e-06
ko04730	Long-term depression	26/931	78/7206	2.43293907114e-06
ko05322	Systemic lupus erythematosus	3/931	151/7206	3.26915368409e-06
ko04072	Phospholipase D signaling pathway	49/931	197/7206	4.04042982275e-06
ko04010	MAPK signaling pathway	69/931	321/7206	1.19005406084e-05
ko04970	Salivary secretion	28/931	95/7206	1.65536256213e-05
ko03013	RNA transport	5/931	166/7206	1.73196150777e-05
ko05030	Cocaine addiction	23/931	73/7206	2.61393602056e-05
ko04742	Taste transduction	20/931	61/7206	4.59955041167e-05
ko04710	Circadian rhythm	16/931	43/7206	4.64508525943e-05
ko04014	Ras signaling pathway	60/931	279/7206	5.20442722294e-05
ko04022	cGMP-PKG signaling pathway	48/931	216/7206	0.000118251236201
ko05203	Viral carcinogenesis	17/931	277/7206	0.000242744202169
ko04925	Aldosterone synthesis and secretion	27/931	105/7206	0.00033423872614
ko04972	Pancreatic secretion	28/931	111/7206	0.000471977614431
ko04971	Gastric acid secretion	25/931	98/7206	0.000661108917789
ko04966	Collecting duct acid secretion	10/931	26/7206	0.000927408156811
ko00562	Inositol phosphate metabolism	23/931	89/7206	0.00112801309907
ko05014	Amyotrophic lateral sclerosis (ALS)	20/931	74/7206	0.00124572574247
ko04960	Aldosterone-regulated sodium reabsorption	13/931	41/7206	0.00138475377702
ko05168	Herpes simplex infection	10/931	182/7206	0.00155286348978
ko04745	Phototransduction - fly	12/931	38/7206	0.00218169758576
ko04964	Proximal tubule bicarbonate reclamation	10/931	29/7206	0.00243173734011
ko04141	Protein processing in endoplasmic reticulum	11/931	184/7206	0.00257023756138
ko04612	Antigen processing and presentation	2/931	77/7206	0.00317706484817
ko04015	Rap1 signaling pathway	53/931	278/7206	0.0033385475981
ko04750	Inflammatory mediator regulation of TRP channels	27/931	122/7206	0.00399562971062
ko05231	Choline metabolism in cancer	29/931	134/7206	0.00405469949235
ko04744	Phototransduction	11/931	36/7206	0.00439377840531
ko04540	Gap junction	28/931	128/7206	0.00473084155188
ko05164	Influenza A	10/931	167/7206	0.00482510605765
ko04621	NOD-like receptor signaling pathway	9/931	157/7206	0.0052355275561
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/931	14/7206	0.00546406949439
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/931	79/7206	0.00613154025741
ko04071	Sphingolipid signaling pathway	33/931	162/7206	0.00629065814951
ko05110	Vibrio cholerae infection	16/931	63/7206	0.00689976198886
ko05230	Central carbon metabolism in cancer	19/931	81/7206	0.00742798335904
ko00280	Valine, leucine and isoleucine degradation	1/931	54/7206	0.00772390425103
ko04973	Carbohydrate digestion and absorption	12/931	42/7206	0.00840833574699
ko04260	Cardiac muscle contraction	22/931	98/7206	0.00896876317851
ko04120	Ubiquitin mediated proteolysis	8/931	138/7206	0.0097837153398
ko04919	Thyroid hormone signaling pathway	29/931	143/7206	0.0114319431429
ko04915	Estrogen signaling pathway	27/931	131/7206	0.0119738326385
ko04110	Cell cycle	9/931	145/7206	0.0119815977514
ko04722	Neurotrophin signaling pathway	31/931	160/7206	0.0171084766764
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/931	59/7206	0.0187430140233
ko04711	Circadian rhythm - fly	5/931	13/7206	0.0187518891425
ko04666	Fc gamma R-mediated phagocytosis	25/931	122/7206	0.0194853933807
ko04626	Plant-pathogen interaction	6/931	18/7206	0.0214546970642
ko04930	Type II diabetes mellitus	13/931	54/7206	0.0227330818653
ko05016	Huntington's disease	17/931	215/7206	0.0231204624719
ko05144	Malaria	1/931	45/7206	0.0248386981159
ko03420	Nucleotide excision repair	1/931	46/7206	0.0251025927898
ko05214	Glioma	17/931	79/7206	0.0279343596589
ko04012	ErbB signaling pathway	22/931	109/7206	0.0299061755943
ko04371	Apelin signaling pathway	33/931	177/7206	0.0301727880112
ko04922	Glucagon signaling pathway	25/931	128/7206	0.0323335862472
ko05210	Colorectal cancer	18/931	86/7206	0.0341854656285
ko04146	Peroxisome	5/931	89/7206	0.0377464011642
ko03022	Basal transcription factors	1/931	44/7206	0.0382477642838
ko04217	Necroptosis	14/931	178/7206	0.0413363142075
ko00240	Pyrimidine metabolism	7/931	110/7206	0.0433363692315
ko05169	Epstein-Barr virus infection	17/931	206/7206	0.0446573418168
ko04064	NF-kappa B signaling pathway	6/931	96/7206	0.0467471135352