ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	149/939	423/7206	7.9981640382e-34
ko05033	Nicotine addiction	44/939	56/7206	5.48157307085e-29
ko04724	Glutamatergic synapse	76/939	152/7206	8.01140719031e-29
ko05032	Morphine addiction	58/939	110/7206	9.69285961704e-24
ko04727	GABAergic synapse	55/939	110/7206	4.04084563585e-21
ko04728	Dopaminergic synapse	72/939	185/7206	2.46603210006e-19
ko04723	Retrograde endocannabinoid signaling	69/939	175/7206	6.20320311974e-19
ko04721	Synaptic vesicle cycle	43/939	80/7206	2.57941646256e-18
ko04713	Circadian entrainment	57/939	136/7206	2.81270067408e-17
ko04725	Cholinergic synapse	62/939	160/7206	1.10083440726e-16
ko04744	Phototransduction	25/939	36/7206	8.08636850594e-15
ko04726	Serotonergic synapse	50/939	137/7206	1.64135155179e-12
ko04024	cAMP signaling pathway	78/939	279/7206	1.82141675233e-11
ko04742	Taste transduction	29/939	61/7206	4.91695705595e-11
ko04911	Insulin secretion	42/939	117/7206	1.88940858326e-10
ko04020	Calcium signaling pathway	72/939	265/7206	3.34459691578e-10
ko05203	Viral carcinogenesis	9/939	277/7206	2.6012534328e-08
ko03040	Spliceosome	1/939	145/7206	5.80620367577e-08
ko04514	Cell adhesion molecules (CAMs)	40/939	130/7206	8.97592736057e-08
ko04921	Oxytocin signaling pathway	54/939	209/7206	3.64664450981e-07
ko05031	Amphetamine addiction	30/939	91/7206	6.51565729949e-07
ko05030	Cocaine addiction	26/939	73/7206	6.74492419215e-07
ko03013	RNA transport	4/939	166/7206	2.03295645281e-06
ko04720	Long-term potentiation	30/939	99/7206	5.60543519421e-06
ko04261	Adrenergic signaling in cardiomyocytes	50/939	205/7206	7.09544088238e-06
ko04120	Ubiquitin mediated proteolysis	3/939	138/7206	9.8356679374e-06
ko05164	Influenza A	5/939	167/7206	1.16587114844e-05
ko05322	Systemic lupus erythematosus	4/939	151/7206	1.32725195062e-05
ko04070	Phosphatidylinositol signaling system	31/939	112/7206	2.76480348229e-05
ko04621	NOD-like receptor signaling pathway	5/939	157/7206	3.41564802088e-05
ko04966	Collecting duct acid secretion	12/939	26/7206	3.73089458944e-05
ko05168	Herpes simplex infection	7/939	182/7206	4.52596675545e-05
ko05205	Proteoglycans in cancer	15/939	271/7206	6.51540840116e-05
ko04970	Salivary secretion	27/939	95/7206	7.42822530933e-05
ko04971	Gastric acid secretion	27/939	98/7206	0.000106410986995
ko04141	Protein processing in endoplasmic reticulum	8/939	184/7206	0.000131169709564
ko04964	Proximal tubule bicarbonate reclamation	12/939	29/7206	0.000137765594246
ko04060	Cytokine-cytokine receptor interaction	9/939	191/7206	0.000180722257409
ko04610	Complement and coagulation cascades	1/939	79/7206	0.000316067512764
ko05014	Amyotrophic lateral sclerosis (ALS)	21/939	74/7206	0.000373197876332
ko04110	Cell cycle	6/939	145/7206	0.000431720773643
ko04972	Pancreatic secretion	28/939	111/7206	0.000499114712808
ko04072	Phospholipase D signaling pathway	43/939	197/7206	0.0005256940607
ko04740	Olfactory transduction	22/939	80/7206	0.000579241313416
ko05161	Hepatitis B	9/939	173/7206	0.000858595750229
ko04730	Long-term depression	21/939	78/7206	0.000965717786296
ko04976	Bile secretion	21/939	80/7206	0.00123341005558
ko05166	HTLV-I infection	21/939	292/7206	0.0017890590562
ko04925	Aldosterone synthesis and secretion	25/939	105/7206	0.00202008227609
ko05169	Epstein-Barr virus infection	13/939	206/7206	0.00221822277103
ko04010	MAPK signaling pathway	60/939	321/7206	0.00294941460532
ko04612	Antigen processing and presentation	2/939	77/7206	0.00320110265119
ko04260	Cardiac muscle contraction	23/939	98/7206	0.00381524607001
ko04360	Axon guidance	46/939	233/7206	0.00387611616369
ko05140	Leishmaniasis	2/939	75/7206	0.00484304489848
ko04064	NF-kappa B signaling pathway	4/939	96/7206	0.00564056231385
ko04630	Jak-STAT signaling pathway	7/939	132/7206	0.00567428693995
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/939	14/7206	0.00570466975224
ko05162	Measles	6/939	120/7206	0.00579068449668
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/939	79/7206	0.00648942432831
ko04022	cGMP-PKG signaling pathway	42/939	216/7206	0.0072712118518
ko04217	Necroptosis	12/939	178/7206	0.00922188526599
ko04710	Circadian rhythm	12/939	43/7206	0.00960933492025
ko04745	Phototransduction - fly	11/939	38/7206	0.0122585821684
ko04930	Type II diabetes mellitus	14/939	54/7206	0.0125144765236
ko04115	p53 signaling pathway	3/939	74/7206	0.0149094887123
ko05133	Pertussis	4/939	87/7206	0.0152928401584
ko00562	Inositol phosphate metabolism	20/939	89/7206	0.0159808279306
ko00260	Glycine, serine and threonine metabolism	1/939	48/7206	0.0167905639822
ko05219	Bladder cancer	1/939	48/7206	0.0167905639822
ko04014	Ras signaling pathway	50/939	279/7206	0.0179474115428
ko04711	Circadian rhythm - fly	5/939	13/7206	0.0194161281297
ko00330	Arginine and proline metabolism	2/939	61/7206	0.0200298560785
ko00310	Lysine degradation	3/939	73/7206	0.0213444028554
ko05110	Vibrio cholerae infection	15/939	63/7206	0.0215307476284
ko04218	Cellular senescence	13/939	177/7206	0.023040963972
ko05016	Huntington's disease	17/939	215/7206	0.0231350294311
ko05144	Malaria	1/939	45/7206	0.0247977892883
ko00071	Fatty acid degradation	1/939	45/7206	0.0247977892883
ko04510	Focal adhesion	20/939	240/7206	0.024948921961
ko03420	Nucleotide excision repair	1/939	46/7206	0.0252473287402
ko04140	Autophagy - animal	12/939	164/7206	0.0254866475641
ko05200	Pathways in cancer	48/939	492/7206	0.0261743249016
ko05418	Fluid shear stress and atherosclerosis	13/939	173/7206	0.0291804258182
ko00240	Pyrimidine metabolism	7/939	110/7206	0.0323149858074
ko04210	Apoptosis	14/939	180/7206	0.0327764985565
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/939	182/7206	0.0331967302017
ko05231	Choline metabolism in cancer	26/939	134/7206	0.0369422912507
ko04657	IL-17 signaling pathway	5/939	87/7206	0.0376140370797
ko04146	Peroxisome	5/939	89/7206	0.0378957787104
ko03022	Basal transcription factors	1/939	44/7206	0.0387398309852
ko00280	Valine, leucine and isoleucine degradation	2/939	54/7206	0.0404881386222
ko00480	Glutathione metabolism	2/939	55/7206	0.0412803507807
ko05416	Viral myocarditis	2/939	55/7206	0.0412803507807
ko05145	Toxoplasmosis	9/939	126/7206	0.0453226669009
ko04658	Th1 and Th2 cell differentiation	6/939	96/7206	0.0466177231705
ko04915	Estrogen signaling pathway	25/939	131/7206	0.048162297546