ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	59/675	152/7206	4.08207100528e-23
ko04721	Synaptic vesicle cycle	38/675	80/7206	6.86671702191e-19
ko05033	Nicotine addiction	31/675	56/7206	4.00180758805e-18
ko04080	Neuroactive ligand-receptor interaction	93/675	423/7206	8.82327549086e-16
ko04727	GABAergic synapse	41/675	110/7206	1.19045055344e-15
ko04728	Dopaminergic synapse	54/675	185/7206	6.71169640842e-15
ko04713	Circadian entrainment	45/675	136/7206	8.20926053429e-15
ko04744	Phototransduction	22/675	36/7206	1.84347973244e-14
ko05032	Morphine addiction	39/675	110/7206	4.12642688214e-14
ko04723	Retrograde endocannabinoid signaling	49/675	175/7206	7.28764363593e-13
ko04725	Cholinergic synapse	44/675	160/7206	2.20612006524e-11
ko04911	Insulin secretion	36/675	117/7206	4.6794597464e-11
ko04024	cAMP signaling pathway	59/675	279/7206	1.34710891421e-09
ko04726	Serotonergic synapse	34/675	137/7206	7.31491150745e-08
ko04740	Olfactory transduction	23/675	80/7206	6.07061646105e-07
ko04261	Adrenergic signaling in cardiomyocytes	42/675	205/7206	1.04716856121e-06
ko04970	Salivary secretion	25/675	95/7206	1.23947056088e-06
ko05203	Viral carcinogenesis	6/675	277/7206	1.56991971396e-06
ko05031	Amphetamine addiction	24/675	91/7206	1.93784373995e-06
ko04964	Proximal tubule bicarbonate reclamation	12/675	29/7206	4.80654729503e-06
ko05030	Cocaine addiction	20/675	73/7206	7.41420801198e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	20/675	74/7206	9.28485479985e-06
ko04720	Long-term potentiation	24/675	99/7206	9.5279861468e-06
ko05322	Systemic lupus erythematosus	1/675	151/7206	1.23738983785e-05
ko03040	Spliceosome	1/675	145/7206	1.73292167157e-05
ko05164	Influenza A	2/675	167/7206	1.9984366266e-05
ko04742	Taste transduction	17/675	61/7206	2.80255661787e-05
ko04921	Oxytocin signaling pathway	39/675	209/7206	2.89509920437e-05
ko04120	Ubiquitin mediated proteolysis	1/675	138/7206	4.02826072789e-05
ko05168	Herpes simplex infection	3/675	182/7206	4.41206181374e-05
ko04966	Collecting duct acid secretion	10/675	26/7206	6.43403416497e-05
ko04925	Aldosterone synthesis and secretion	23/675	105/7206	0.000111793814723
ko05166	HTLV-I infection	10/675	292/7206	0.000124109884799
ko04020	Calcium signaling pathway	44/675	265/7206	0.000143566865884
ko04514	Cell adhesion molecules (CAMs)	26/675	130/7206	0.000180013336996
ko04972	Pancreatic secretion	23/675	111/7206	0.000214969634152
ko04022	cGMP-PKG signaling pathway	36/675	216/7206	0.000522189093852
ko04140	Autophagy - animal	4/675	164/7206	0.000623329765082
ko04971	Gastric acid secretion	20/675	98/7206	0.000685792283335
ko04924	Renin secretion	18/675	86/7206	0.00104471181298
ko04621	NOD-like receptor signaling pathway	4/675	157/7206	0.00124473202622
ko04668	TNF signaling pathway	2/675	120/7206	0.00127076295463
ko05205	Proteoglycans in cancer	11/675	271/7206	0.00129850508409
ko04976	Bile secretion	17/675	80/7206	0.00133973303318
ko05161	Hepatitis B	5/675	173/7206	0.00134697438412
ko05169	Epstein-Barr virus infection	7/675	206/7206	0.00143677009377
ko04060	Cytokine-cytokine receptor interaction	6/675	191/7206	0.00143816797385
ko04810	Regulation of actin cytoskeleton	11/675	264/7206	0.00169796038955
ko04141	Protein processing in endoplasmic reticulum	6/675	184/7206	0.00192578839024
ko04745	Phototransduction - fly	10/675	38/7206	0.00203384118711
ko04974	Protein digestion and absorption	19/675	96/7206	0.00207147131274
ko04260	Cardiac muscle contraction	19/675	98/7206	0.00229919980429
ko04730	Long-term depression	16/675	78/7206	0.00245531791455
ko05215	Prostate cancer	2/675	111/7206	0.00262893961598
ko04210	Apoptosis	6/675	180/7206	0.00264244913693
ko03013	RNA transport	5/675	166/7206	0.00265300506703
ko04978	Mineral absorption	10/675	40/7206	0.00307264908079
ko04010	MAPK signaling pathway	46/675	321/7206	0.00311975608009
ko05220	Chronic myeloid leukemia	1/675	85/7206	0.00416754615912
ko04610	Complement and coagulation cascades	1/675	79/7206	0.00604760708056
ko03008	Ribosome biogenesis in eukaryotes	1/675	79/7206	0.00604760708056
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/675	182/7206	0.00647025346894
ko05110	Vibrio cholerae infection	13/675	63/7206	0.00685241101941
ko05211	Renal cell carcinoma	2/675	96/7206	0.00764989162089
ko05140	Leishmaniasis	1/675	75/7206	0.0088601656039
ko01524	Platinum drug resistance	1/675	76/7206	0.00891529299374
ko04612	Antigen processing and presentation	1/675	77/7206	0.0090633293523
ko04110	Cell cycle	5/675	145/7206	0.00913817219827
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/675	59/7206	0.0105046253437
ko05418	Fluid shear stress and atherosclerosis	7/675	173/7206	0.0115907671506
ko04660	T cell receptor signaling pathway	4/675	124/7206	0.0124689154806
ko04657	IL-17 signaling pathway	2/675	87/7206	0.0155641804707
ko04146	Peroxisome	2/675	89/7206	0.0157714719899
ko05222	Small cell lung cancer	2/675	89/7206	0.0157714719899
ko01521	EGFR tyrosine kinase inhibitor resistance	3/675	106/7206	0.0171608142637
ko04371	Apelin signaling pathway	26/675	177/7206	0.018352934742
ko05223	Non-small cell lung cancer	1/675	66/7206	0.0189344381184
ko04611	Platelet activation	7/675	163/7206	0.0204096801698
ko04540	Gap junction	20/675	128/7206	0.0206155372075
ko04626	Plant-pathogen interaction	5/675	18/7206	0.0216953576933
ko04630	Jak-STAT signaling pathway	5/675	132/7206	0.0228596026009
ko04218	Cellular senescence	8/675	177/7206	0.0252534642114
ko04330	Notch signaling pathway	1/675	62/7206	0.027597969582
ko00561	Glycerolipid metabolism	1/675	63/7206	0.0277675397958
ko05120	Epithelial cell signaling in Helicobacter pylori infection	15/675	92/7206	0.0293513254084
ko04510	Focal adhesion	13/675	240/7206	0.0317284443057
ko04064	NF-kappa B signaling pathway	3/675	96/7206	0.0326324710322
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/675	14/7206	0.0356708806704
ko04150	mTOR signaling pathway	9/675	184/7206	0.0389092061879
ko04211	Longevity regulating pathway	5/675	123/7206	0.0412553465183
ko01522	Endocrine resistance	5/675	124/7206	0.041559477166
ko04217	Necroptosis	9/675	178/7206	0.0494548434788