ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	169/923	423/7206	2.78906470859e-48
ko04724	Glutamatergic synapse	76/923	152/7206	2.48605675885e-29
ko05033	Nicotine addiction	44/923	56/7206	2.60385393116e-29
ko05032	Morphine addiction	58/923	110/7206	3.94705960269e-24
ko04727	GABAergic synapse	56/923	110/7206	2.38282085407e-22
ko04024	cAMP signaling pathway	93/923	279/7206	9.4199281834e-20
ko04728	Dopaminergic synapse	70/923	185/7206	1.87322608017e-18
ko04713	Circadian entrainment	58/923	136/7206	2.35595961128e-18
ko04723	Retrograde endocannabinoid signaling	66/923	175/7206	2.26277143246e-17
ko04725	Cholinergic synapse	61/923	160/7206	2.11756197133e-16
ko04721	Synaptic vesicle cycle	40/923	80/7206	6.01660088437e-16
ko04020	Calcium signaling pathway	83/923	265/7206	7.74836945332e-16
ko04726	Serotonergic synapse	51/923	137/7206	2.00708386175e-13
ko04911	Insulin secretion	45/923	117/7206	1.42424340412e-12
ko04742	Taste transduction	29/923	61/7206	3.20537838842e-11
ko04261	Adrenergic signaling in cardiomyocytes	62/923	205/7206	3.40486002998e-11
ko04921	Oxytocin signaling pathway	62/923	209/7206	5.9662888218e-11
ko04360	Axon guidance	63/923	233/7206	2.98635012343e-09
ko04744	Phototransduction	18/923	36/7206	6.90745804871e-08
ko03040	Spliceosome	1/923	145/7206	9.38866922214e-08
ko04970	Salivary secretion	32/923	95/7206	1.05085282775e-07
ko05203	Viral carcinogenesis	10/923	277/7206	1.77900478538e-07
ko05031	Amphetamine addiction	30/923	91/7206	4.47709741332e-07
ko05030	Cocaine addiction	26/923	73/7206	4.80463538777e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/923	74/7206	6.52048033101e-07
ko04022	cGMP-PKG signaling pathway	53/923	216/7206	2.14315987844e-06
ko03013	RNA transport	4/923	166/7206	3.03128269664e-06
ko05164	Influenza A	4/923	167/7206	3.06044372211e-06
ko04720	Long-term potentiation	30/923	99/7206	4.45501314366e-06
ko04971	Gastric acid secretion	29/923	98/7206	9.39706250936e-06
ko04010	MAPK signaling pathway	69/923	321/7206	1.06497341854e-05
ko05168	Herpes simplex infection	6/923	182/7206	1.41425021894e-05
ko05322	Systemic lupus erythematosus	4/923	151/7206	1.98164975746e-05
ko04972	Pancreatic secretion	30/923	111/7206	4.3601421723e-05
ko04260	Cardiac muscle contraction	27/923	98/7206	8.74482924042e-05
ko04730	Long-term depression	23/923	78/7206	9.45405579626e-05
ko05169	Epstein-Barr virus infection	10/923	206/7206	0.000184082293409
ko04141	Protein processing in endoplasmic reticulum	8/923	184/7206	0.000185384843406
ko04060	Cytokine-cytokine receptor interaction	9/923	191/7206	0.000252019541511
ko04514	Cell adhesion molecules (CAMs)	32/923	130/7206	0.000267255663755
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/923	79/7206	0.000279935162907
ko04072	Phospholipase D signaling pathway	43/923	197/7206	0.000324804033678
ko04120	Ubiquitin mediated proteolysis	5/923	138/7206	0.000417308597077
ko04924	Renin secretion	23/923	86/7206	0.000462200306608
ko05414	Dilated cardiomyopathy	28/923	112/7206	0.000476826626528
ko04070	Phosphatidylinositol signaling system	28/923	112/7206	0.000476826626528
ko04621	NOD-like receptor signaling pathway	7/923	157/7206	0.000635189415766
ko04540	Gap junction	30/923	128/7206	0.000751171184341
ko04925	Aldosterone synthesis and secretion	26/923	105/7206	0.000958411850984
ko05205	Proteoglycans in cancer	18/923	271/7206	0.00112723338768
ko05162	Measles	5/923	120/7206	0.00219632330181
ko04612	Antigen processing and presentation	2/923	77/7206	0.00317800767167
ko04610	Complement and coagulation cascades	2/923	79/7206	0.00330672936394
ko04740	Olfactory transduction	20/923	80/7206	0.00346155728111
ko00330	Arginine and proline metabolism	1/923	61/7206	0.00352402374762
ko04966	Collecting duct acid secretion	9/923	26/7206	0.00364291868278
ko05161	Hepatitis B	10/923	173/7206	0.0036939912468
ko04146	Peroxisome	3/923	89/7206	0.00373211160702
ko04014	Ras signaling pathway	52/923	279/7206	0.00447082947748
ko04923	Regulation of lipolysis in adipocytes	19/923	77/7206	0.00507067720908
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/923	14/7206	0.00523125016107
ko04510	Focal adhesion	17/923	240/7206	0.0056934770576
ko00240	Pyrimidine metabolism	5/923	110/7206	0.00585665466809
ko05215	Prostate cancer	5/923	111/7206	0.00593247264108
ko04976	Bile secretion	19/923	80/7206	0.00633802200494
ko00310	Lysine degradation	2/923	73/7206	0.00705110343986
ko04964	Proximal tubule bicarbonate reclamation	9/923	29/7206	0.00819359513606
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/923	59/7206	0.00908493579806
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/923	182/7206	0.00934526306286
ko04915	Estrogen signaling pathway	27/923	131/7206	0.0114377098947
ko05110	Vibrio cholerae infection	15/923	63/7206	0.0133909437754
ko04140	Autophagy - animal	11/923	164/7206	0.0173666900355
ko04064	NF-kappa B signaling pathway	5/923	96/7206	0.0206127959286
ko04214	Apoptosis - fly	3/923	72/7206	0.0210948263582
ko03018	RNA degradation	4/923	84/7206	0.0211822443037
ko04115	p53 signaling pathway	3/923	74/7206	0.021382954312
ko05140	Leishmaniasis	3/923	75/7206	0.0219192593809
ko05410	Hypertrophic cardiomyopathy (HCM)	21/923	100/7206	0.0222666686155
ko04217	Necroptosis	13/923	178/7206	0.0229889121421
ko04745	Phototransduction - fly	10/923	38/7206	0.0238277818107
ko05144	Malaria	1/923	45/7206	0.0249484558256
ko00071	Fatty acid degradation	1/923	45/7206	0.0249484558256
ko03420	Nucleotide excision repair	1/923	46/7206	0.0250297344689
ko00260	Glycine, serine and threonine metabolism	1/923	48/7206	0.0265849819138
ko05131	Shigellosis	4/923	82/7206	0.0293299543078
ko04110	Cell cycle	10/923	145/7206	0.0319374587858
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/923	15/7206	0.0339887104245
ko03022	Basal transcription factors	1/923	44/7206	0.0378473671353
ko00280	Valine, leucine and isoleucine degradation	2/923	54/7206	0.0404914132922
ko00480	Glutathione metabolism	2/923	55/7206	0.0407639254022
ko05231	Choline metabolism in cancer	25/923	134/7206	0.0493456104877