ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 22/238 120/7206 3.53504015081e-11 ko04621 NOD-like receptor signaling pathway 25/238 157/7206 3.84370091846e-11 ko04380 Osteoclast differentiation 22/238 134/7206 3.33182523558e-10 ko04217 Necroptosis 22/238 178/7206 7.54220088347e-08 ko04210 Apoptosis 22/238 180/7206 9.23556894259e-08 ko05164 Influenza A 20/238 167/7206 5.092677065e-07 ko05133 Pertussis 14/238 87/7206 7.92428259127e-07 ko04060 Cytokine-cytokine receptor interaction 21/238 191/7206 1.09979873546e-06 ko04064 NF-kappa B signaling pathway 14/238 96/7206 2.6898267146e-06 ko05132 Salmonella infection 14/238 98/7206 3.45779547929e-06 ko04620 Toll-like receptor signaling pathway 14/238 100/7206 4.415242446e-06 ko04657 IL-17 signaling pathway 13/238 87/7206 4.67065241755e-06 ko04623 Cytosolic DNA-sensing pathway 9/238 41/7206 5.59140389507e-06 ko05152 Tuberculosis 19/238 187/7206 1.16548657904e-05 ko04660 T cell receptor signaling pathway 15/238 124/7206 1.25731012281e-05 ko05131 Shigellosis 12/238 82/7206 1.36125597149e-05 ko05161 Hepatitis B 18/238 173/7206 1.43766380315e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/238 191/7206 1.58024995434e-05 ko05134 Legionellosis 11/238 74/7206 2.69094754094e-05 ko04115 p53 signaling pathway 11/238 74/7206 2.69094754094e-05 ko04662 B cell receptor signaling pathway 12/238 88/7206 2.8311485258e-05 ko05168 Herpes simplex infection 18/238 182/7206 2.87748639132e-05 ko05142 Chagas disease (American trypanosomiasis) 14/238 130/7206 9.04293409446e-05 ko04630 Jak-STAT signaling pathway 14/238 132/7206 0.000106802501206 ko04624 Toll and Imd signaling pathway 8/238 49/7206 0.000175784486103 ko05120 Epithelial cell signaling in Helicobacter pylori infection 11/238 92/7206 0.000204967766037 ko05145 Toxoplasmosis 13/238 126/7206 0.00024841205562 ko04932 Non-alcoholic fatty liver disease (NAFLD) 16/238 182/7206 0.000319489452133 ko05100 Bacterial invasion of epithelial cells 11/238 99/7206 0.000392253417384 ko04933 AGE-RAGE signaling pathway in diabetic complications 13/238 135/7206 0.000489285113848 ko05162 Measles 12/238 120/7206 0.00057122107091 ko05323 Rheumatoid arthritis 10/238 89/7206 0.000657552328552 ko04666 Fc gamma R-mediated phagocytosis 12/238 122/7206 0.000663505965734 ko04722 Neurotrophin signaling pathway 14/238 160/7206 0.000789865453339 ko04215 Apoptosis - multiple species 7/238 47/7206 0.000798465083494 ko04622 RIG-I-like receptor signaling pathway 8/238 62/7206 0.000910849056404 ko05160 Hepatitis C 13/238 153/7206 0.00158268273027 ko04020 Calcium signaling pathway 1/238 265/7206 0.00236293702918 ko04080 Neuroactive ligand-receptor interaction 4/238 423/7206 0.00281373121114 ko01524 Platinum drug resistance 8/238 76/7206 0.00341916750673 ko04062 Chemokine signaling pathway 15/238 201/7206 0.00365552782899 ko05130 Pathogenic Escherichia coli infection 8/238 77/7206 0.00370953024009 ko04931 Insulin resistance 11/238 137/7206 0.00549331549855 ko05210 Colorectal cancer 8/238 86/7206 0.00726180405459 ko04144 Endocytosis 21/238 342/7206 0.00737338473797 ko05418 Fluid shear stress and atherosclerosis 13/238 173/7206 0.0074364049138 ko04920 Adipocytokine signaling pathway 8/238 89/7206 0.00888541815838 ko05140 Leishmaniasis 7/238 75/7206 0.0115559728113 ko04658 Th1 and Th2 cell differentiation 8/238 96/7206 0.0137138732613 ko04010 MAPK signaling pathway 18/238 321/7206 0.024480394284 ko05203 Viral carcinogenesis 16/238 277/7206 0.0252029829561 ko04672 Intestinal immune network for IgA production 4/238 37/7206 0.0326461005792 ko04142 Lysosome 10/238 151/7206 0.0334797776225 ko04670 Leukocyte transendothelial migration 10/238 151/7206 0.0334797776225 ko05321 Inflammatory bowel disease (IBD) 5/238 56/7206 0.0367184120473 ko04650 Natural killer cell mediated cytotoxicity 7/238 97/7206 0.0408802261148 ko05020 Prion diseases 4/238 40/7206 0.0418692418372 ko05146 Amoebiasis 7/238 99/7206 0.0448616739558 ko04550 Signaling pathways regulating pluripotency of stem cells 1/238 165/7206 0.0453199690177