ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	160/898	423/7206	1.42288980078e-43
ko05033	Nicotine addiction	42/898	56/7206	4.4914729923e-27
ko04724	Glutamatergic synapse	67/898	152/7206	1.06784758342e-22
ko04721	Synaptic vesicle cycle	41/898	80/7206	3.02788861222e-17
ko05032	Morphine addiction	49/898	110/7206	4.02219125249e-17
ko04727	GABAergic synapse	48/898	110/7206	2.35394912524e-16
ko04728	Dopaminergic synapse	65/898	185/7206	6.02244481162e-16
ko04024	cAMP signaling pathway	79/898	279/7206	3.79298955018e-13
ko04713	Circadian entrainment	49/898	136/7206	8.81668283227e-13
ko04723	Retrograde endocannabinoid signaling	56/898	175/7206	5.60144095835e-12
ko04725	Cholinergic synapse	52/898	160/7206	1.69952338126e-11
ko04911	Insulin secretion	39/898	117/7206	2.68006509374e-09
ko04726	Serotonergic synapse	43/898	137/7206	3.36288791664e-09
ko04742	Taste transduction	26/898	61/7206	3.49588093221e-09
ko04360	Axon guidance	60/898	233/7206	2.3922293723e-08
ko04020	Calcium signaling pathway	65/898	265/7206	3.69111714571e-08
ko03040	Spliceosome	1/898	145/7206	1.4388180653e-07
ko05031	Amphetamine addiction	30/898	91/7206	2.44315548343e-07
ko04261	Adrenergic signaling in cardiomyocytes	52/898	205/7206	2.74181063485e-07
ko05030	Cocaine addiction	26/898	73/7206	2.78125320855e-07
ko05203	Viral carcinogenesis	10/898	277/7206	3.62709333118e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/898	74/7206	1.46971698448e-06
ko04010	MAPK signaling pathway	70/898	321/7206	1.53231103153e-06
ko04514	Cell adhesion molecules (CAMs)	36/898	130/7206	2.47655041831e-06
ko04921	Oxytocin signaling pathway	50/898	209/7206	3.36536248494e-06
ko05322	Systemic lupus erythematosus	3/898	151/7206	4.82649152819e-06
ko05168	Herpes simplex infection	5/898	182/7206	6.08798562906e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/898	79/7206	1.88087501594e-05
ko03013	RNA transport	5/898	166/7206	2.49783900198e-05
ko04060	Cytokine-cytokine receptor interaction	7/898	191/7206	3.25831458521e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/898	14/7206	8.47439210263e-05
ko04970	Salivary secretion	26/898	95/7206	0.000107627220883
ko04720	Long-term potentiation	26/898	99/7206	0.000161910427044
ko04141	Protein processing in endoplasmic reticulum	8/898	184/7206	0.000253649683635
ko05164	Influenza A	7/898	167/7206	0.000338603044555
ko03008	Ribosome biogenesis in eukaryotes	1/898	79/7206	0.000491357864492
ko04120	Ubiquitin mediated proteolysis	5/898	138/7206	0.000593759327233
ko00240	Pyrimidine metabolism	3/898	110/7206	0.000649157544777
ko04966	Collecting duct acid secretion	10/898	26/7206	0.000694743732486
ko04022	cGMP-PKG signaling pathway	44/898	216/7206	0.000759551385179
ko04621	NOD-like receptor signaling pathway	7/898	157/7206	0.000891507459851
ko04744	Phototransduction	12/898	36/7206	0.000932908887449
ko05205	Proteoglycans in cancer	17/898	271/7206	0.000965428141814
ko04730	Long-term depression	20/898	78/7206	0.00144028256206
ko04014	Ras signaling pathway	53/898	279/7206	0.00155510780174
ko01200	Carbon metabolism	5/898	128/7206	0.00163657271072
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/898	59/7206	0.00215013791125
ko03018	RNA degradation	2/898	84/7206	0.00228180278172
ko04924	Renin secretion	21/898	86/7206	0.00249838599615
ko05169	Epstein-Barr virus infection	12/898	206/7206	0.00251063882929
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/898	182/7206	0.0028536644699
ko04260	Cardiac muscle contraction	23/898	98/7206	0.00287167648438
ko04972	Pancreatic secretion	25/898	111/7206	0.00324635566547
ko04140	Autophagy - animal	9/898	164/7206	0.00391864160887
ko04612	Antigen processing and presentation	2/898	77/7206	0.00474894460932
ko04971	Gastric acid secretion	22/898	98/7206	0.00503997430868
ko04146	Peroxisome	3/898	89/7206	0.00542420238703
ko04350	TGF-beta signaling pathway	4/898	103/7206	0.00604401157176
ko04925	Aldosterone synthesis and secretion	23/898	105/7206	0.00658049747552
ko04214	Apoptosis - fly	2/898	72/7206	0.00677072081904
ko00310	Lysine degradation	2/898	73/7206	0.00678786061153
ko05140	Leishmaniasis	2/898	75/7206	0.00715003393376
ko05321	Inflammatory bowel disease (IBD)	1/898	56/7206	0.00786844533428
ko05414	Dilated cardiomyopathy	24/898	112/7206	0.00855796562966
ko04391	Hippo signaling pathway - fly	20/898	90/7206	0.00912971844584
ko05162	Measles	6/898	120/7206	0.0112102095029
ko04064	NF-kappa B signaling pathway	4/898	96/7206	0.0116205164501
ko00480	Glutathione metabolism	1/898	55/7206	0.0119621509576
ko05145	Toxoplasmosis	7/898	126/7206	0.0139814769679
ko04217	Necroptosis	12/898	178/7206	0.0157315962113
ko00590	Arachidonic acid metabolism	1/898	52/7206	0.0178105385096
ko00561	Glycerolipid metabolism	2/898	63/7206	0.0201653073249
ko04640	Hematopoietic cell lineage	2/898	64/7206	0.0205128532573
ko05146	Amoebiasis	5/898	99/7206	0.0208568356588
ko04110	Cell cycle	9/898	145/7206	0.021279709952
ko05133	Pertussis	4/898	87/7206	0.0214349052606
ko04964	Proximal tubule bicarbonate reclamation	8/898	29/7206	0.0219771091562
ko04950	Maturity onset diabetes of the young	8/898	29/7206	0.0219771091562
ko04611	Platelet activation	11/898	163/7206	0.0224180137924
ko05161	Hepatitis B	12/898	173/7206	0.0260713060119
ko00515	Mannose type O-glycan biosynthesis	7/898	25/7206	0.0290031249655
ko00330	Arginine and proline metabolism	2/898	61/7206	0.0295563065049
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/898	15/7206	0.0305565678368
ko05410	Hypertrophic cardiomyopathy (HCM)	20/898	100/7206	0.0311550379732
ko03022	Basal transcription factors	1/898	44/7206	0.0371884444707
ko04930	Type II diabetes mellitus	12/898	54/7206	0.0375524301757
ko05144	Malaria	1/898	45/7206	0.0379563514753
ko00071	Fatty acid degradation	1/898	45/7206	0.0379563514753
ko03420	Nucleotide excision repair	1/898	46/7206	0.0393354372364
ko04015	Rap1 signaling pathway	46/898	278/7206	0.0412095238747
ko05131	Shigellosis	4/898	82/7206	0.0412845909381
ko04540	Gap junction	24/898	128/7206	0.0413069705882
ko04915	Estrogen signaling pathway	24/898	131/7206	0.0452422248669
ko04630	Jak-STAT signaling pathway	9/898	132/7206	0.0459264386977
ko05418	Fluid shear stress and atherosclerosis	13/898	173/7206	0.0470937407694
ko04072	Phospholipase D signaling pathway	34/898	197/7206	0.0480754980684