ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 24/335 68/7206 1.07473824634e-15 ko04550 Signaling pathways regulating pluripotency of stem cells 33/335 165/7206 4.86226269039e-13 ko04360 Axon guidance 37/335 233/7206 2.65738906904e-11 ko05224 Breast cancer 31/335 174/7206 6.04600894493e-11 ko04340 Hedgehog signaling pathway 17/335 58/7206 5.12719388935e-10 ko04950 Maturity onset diabetes of the young 11/335 29/7206 3.03489470558e-08 ko05200 Pathways in cancer 51/335 492/7206 4.12653085512e-08 ko05202 Transcriptional misregulation in cancer 26/335 188/7206 4.79040284958e-07 ko04330 Notch signaling pathway 14/335 62/7206 6.41374580702e-07 ko04310 Wnt signaling pathway 25/335 181/7206 8.2144939223e-07 ko04390 Hippo signaling pathway 25/335 188/7206 1.68313836754e-06 ko04512 ECM-receptor interaction 15/335 79/7206 2.67928859871e-06 ko04080 Neuroactive ligand-receptor interaction 5/335 423/7206 0.000108413334499 ko04974 Protein digestion and absorption 13/335 96/7206 0.000459070329584 ko04916 Melanogenesis 16/335 142/7206 0.00086331300831 ko04391 Hippo signaling pathway - fly 12/335 90/7206 0.00086915228434 ko00230 Purine metabolism 1/335 194/7206 0.00157058462657 ko04072 Phospholipase D signaling pathway 1/335 197/7206 0.00159670220845 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/335 182/7206 0.00348365626314 ko04510 Focal adhesion 21/335 240/7206 0.0045530241949 ko04723 Retrograde endocannabinoid signaling 1/335 175/7206 0.00519480301883 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 5/335 26/7206 0.00618324602276 ko05010 Alzheimer's disease 2/335 202/7206 0.00620210185879 ko04921 Oxytocin signaling pathway 2/335 209/7206 0.00652859473419 ko04611 Platelet activation 1/335 163/7206 0.00720077269233 ko04341 Hedgehog signaling pathway - fly 6/335 38/7206 0.00755512821089 ko05222 Small cell lung cancer 10/335 89/7206 0.00798640251315 ko05206 MicroRNAs in cancer 16/335 177/7206 0.00998080103778 ko04020 Calcium signaling pathway 4/335 265/7206 0.0104532477123 ko05012 Parkinson's disease 1/335 155/7206 0.0105034445686 ko05205 Proteoglycans in cancer 22/335 271/7206 0.0112554626713 ko00514 Other types of O-glycan biosynthesis 5/335 30/7206 0.011509572212 ko04141 Protein processing in endoplasmic reticulum 2/335 184/7206 0.0124616074558 ko05166 HTLV-I infection 23/335 292/7206 0.0146084870938 ko04371 Apelin signaling pathway 2/335 177/7206 0.0176328761762 ko04151 PI3K-Akt signaling pathway 28/335 390/7206 0.0186539429384 ko05203 Viral carcinogenesis 5/335 277/7206 0.0187887506375 ko00310 Lysine degradation 8/335 73/7206 0.0193873623345 ko04514 Cell adhesion molecules (CAMs) 12/335 130/7206 0.0194068643014 ko04919 Thyroid hormone signaling pathway 13/335 143/7206 0.0237576420889 ko04062 Chemokine signaling pathway 3/335 201/7206 0.0260151074872 ko05034 Alcoholism 4/335 238/7206 0.0265246316703 ko03410 Base excision repair 5/335 38/7206 0.0300015986883 ko00190 Oxidative phosphorylation 1/335 127/7206 0.0311242888745 ko05142 Chagas disease (American trypanosomiasis) 1/335 130/7206 0.0319265629011 ko04144 Endocytosis 8/335 342/7206 0.0347457393932 ko04071 Sphingolipid signaling pathway 2/335 162/7206 0.0352669270633 ko04140 Autophagy - animal 2/335 164/7206 0.0358821908624 ko04912 GnRH signaling pathway 1/335 122/7206 0.0462372969685 ko04750 Inflammatory mediator regulation of TRP channels 1/335 122/7206 0.0462372969685 ko04022 cGMP-PKG signaling pathway 4/335 216/7206 0.0473850119674 ko05322 Systemic lupus erythematosus 2/335 151/7206 0.0487046686579