ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	40/689	56/7206	5.53570657287e-29
ko04724	Glutamatergic synapse	64/689	152/7206	7.05195318726e-27
ko04080	Neuroactive ligand-receptor interaction	103/689	423/7206	2.19960251703e-20
ko04728	Dopaminergic synapse	61/689	185/7206	3.63370453509e-19
ko04727	GABAergic synapse	44/689	110/7206	9.58805304284e-18
ko04713	Circadian entrainment	49/689	136/7206	2.15252999653e-17
ko05032	Morphine addiction	43/689	110/7206	6.33065121351e-17
ko04723	Retrograde endocannabinoid signaling	54/689	175/7206	1.16045768126e-15
ko04725	Cholinergic synapse	49/689	160/7206	3.59589598068e-14
ko04721	Synaptic vesicle cycle	32/689	80/7206	3.0864113041e-13
ko04911	Insulin secretion	38/689	117/7206	3.91389974219e-12
ko04024	cAMP signaling pathway	62/689	279/7206	1.12422630237e-10
ko04744	Phototransduction	18/689	36/7206	6.25757493256e-10
ko05031	Amphetamine addiction	29/689	91/7206	2.39439544298e-09
ko05030	Cocaine addiction	25/689	73/7206	5.83368633126e-09
ko04726	Serotonergic synapse	36/689	137/7206	1.01749973513e-08
ko04514	Cell adhesion molecules (CAMs)	34/689	130/7206	2.98926905324e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	24/689	74/7206	3.96189827998e-08
ko04921	Oxytocin signaling pathway	46/689	209/7206	5.30000147573e-08
ko04261	Adrenergic signaling in cardiomyocytes	45/689	205/7206	8.0677308164e-08
ko04742	Taste transduction	21/689	61/7206	8.7933727041e-08
ko04720	Long-term potentiation	26/689	99/7206	1.17633044541e-06
ko04360	Axon guidance	46/689	233/7206	1.28830965032e-06
ko05203	Viral carcinogenesis	7/689	277/7206	5.29906561479e-06
ko03040	Spliceosome	1/689	145/7206	1.12344649165e-05
ko05164	Influenza A	2/689	167/7206	1.32456920074e-05
ko04060	Cytokine-cytokine receptor interaction	3/689	191/7206	1.42320916682e-05
ko04010	MAPK signaling pathway	55/689	321/7206	1.50352768245e-05
ko04970	Salivary secretion	23/689	95/7206	2.08439451203e-05
ko04120	Ubiquitin mediated proteolysis	1/689	138/7206	2.54459462152e-05
ko04020	Calcium signaling pathway	46/689	265/7206	6.47638602303e-05
ko03013	RNA transport	3/689	166/7206	8.52825867481e-05
ko05162	Measles	1/689	120/7206	0.000121939949936
ko04260	Cardiac muscle contraction	21/689	98/7206	0.000352186491753
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/689	79/7206	0.000365970831672
ko05322	Systemic lupus erythematosus	3/689	151/7206	0.000370790461684
ko04740	Olfactory transduction	18/689	80/7206	0.000431059838396
ko04964	Proximal tubule bicarbonate reclamation	9/689	29/7206	0.00109583316218
ko04925	Aldosterone synthesis and secretion	21/689	105/7206	0.00109731341801
ko05166	HTLV-I infection	13/689	292/7206	0.00150517314963
ko05168	Herpes simplex infection	6/689	182/7206	0.00193612294049
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/689	182/7206	0.00193612294049
ko04022	cGMP-PKG signaling pathway	35/689	216/7206	0.00200905365033
ko05205	Proteoglycans in cancer	12/689	271/7206	0.00210507942165
ko04745	Phototransduction - fly	10/689	38/7206	0.00237224252731
ko04971	Gastric acid secretion	19/689	98/7206	0.00261522091093
ko04972	Pancreatic secretion	21/689	111/7206	0.00277263768824
ko04621	NOD-like receptor signaling pathway	5/689	157/7206	0.00355905383721
ko04150	mTOR signaling pathway	7/689	184/7206	0.00481349395083
ko04014	Ras signaling pathway	41/689	279/7206	0.0048239198066
ko04630	Jak-STAT signaling pathway	4/689	132/7206	0.00654255940524
ko04140	Autophagy - animal	6/689	164/7206	0.00667033234623
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/689	14/7206	0.00757406386928
ko05169	Epstein-Barr virus infection	9/689	206/7206	0.00774507703136
ko05161	Hepatitis B	7/689	173/7206	0.00861046056498
ko04730	Long-term depression	15/689	78/7206	0.00983051978553
ko04976	Bile secretion	15/689	80/7206	0.0109547842676
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/689	59/7206	0.0114570064056
ko05220	Chronic myeloid leukemia	2/689	85/7206	0.0154764864667
ko04512	ECM-receptor interaction	14/689	79/7206	0.0197748089539
ko04110	Cell cycle	6/689	145/7206	0.0216682148266
ko03018	RNA degradation	2/689	84/7206	0.0227368348121
ko05414	Dilated cardiomyopathy	18/689	112/7206	0.0233328860455
ko00564	Glycerophospholipid metabolism	3/689	99/7206	0.0235692081297
ko05016	Huntington's disease	11/689	215/7206	0.0244216969079
ko04371	Apelin signaling pathway	26/689	177/7206	0.0266779659987
ko00561	Glycerolipid metabolism	1/689	63/7206	0.0282190843551
ko04640	Hematopoietic cell lineage	1/689	64/7206	0.0289940312733
ko04141	Protein processing in endoplasmic reticulum	9/689	184/7206	0.0297696820539
ko04612	Antigen processing and presentation	2/689	77/7206	0.0311476537177
ko04540	Gap junction	20/689	128/7206	0.0317967100602
ko00240	Pyrimidine metabolism	4/689	110/7206	0.03209384119
ko05215	Prostate cancer	4/689	111/7206	0.0324824748364
ko04966	Collecting duct acid secretion	6/689	26/7206	0.0326690214001
ko04064	NF-kappa B signaling pathway	3/689	96/7206	0.0334474509163
ko04930	Type II diabetes mellitus	10/689	54/7206	0.0342711614511
ko04142	Lysosome	7/689	151/7206	0.035280859565
ko05410	Hypertrophic cardiomyopathy (HCM)	16/689	100/7206	0.0378022752806
ko05321	Inflammatory bowel disease (IBD)	1/689	56/7206	0.0399603988283
ko04924	Renin secretion	14/689	86/7206	0.0412545427415
ko04214	Apoptosis - fly	2/689	72/7206	0.0439597536824
ko00310	Lysine degradation	2/689	73/7206	0.0440340523363
ko04146	Peroxisome	3/689	89/7206	0.0446257290781
ko05140	Leishmaniasis	2/689	75/7206	0.0450995376014
ko01524	Platinum drug resistance	2/689	76/7206	0.0460883616796