ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	45/485	152/7206	2.89236658103e-18
ko05033	Nicotine addiction	26/485	56/7206	1.76554490874e-16
ko04721	Synaptic vesicle cycle	29/485	80/7206	9.51842070738e-15
ko04728	Dopaminergic synapse	43/485	185/7206	2.33042167701e-13
ko04727	GABAergic synapse	32/485	110/7206	4.50662953004e-13
ko04723	Retrograde endocannabinoid signaling	39/485	175/7206	1.30275323948e-11
ko05032	Morphine addiction	29/485	110/7206	8.38612199874e-11
ko04713	Circadian entrainment	32/485	136/7206	2.18715014432e-10
ko04911	Insulin secretion	28/485	117/7206	2.00848708797e-09
ko04725	Cholinergic synapse	33/485	160/7206	4.29734346796e-09
ko04726	Serotonergic synapse	30/485	137/7206	5.08513327461e-09
ko04080	Neuroactive ligand-receptor interaction	60/485	423/7206	1.82110446766e-08
ko04261	Adrenergic signaling in cardiomyocytes	34/485	205/7206	6.83210057479e-07
ko04024	cAMP signaling pathway	40/485	279/7206	3.99416385803e-06
ko04514	Cell adhesion molecules (CAMs)	24/485	130/7206	4.66127234051e-06
ko04720	Long-term potentiation	19/485	99/7206	2.60129149031e-05
ko05203	Viral carcinogenesis	4/485	277/7206	4.31886157949e-05
ko04020	Calcium signaling pathway	36/485	265/7206	4.55317892019e-05
ko05030	Cocaine addiction	15/485	73/7206	8.12333273695e-05
ko05031	Amphetamine addiction	17/485	91/7206	9.80354970053e-05
ko04921	Oxytocin signaling pathway	29/485	209/7206	0.000192611767975
ko04966	Collecting duct acid secretion	8/485	26/7206	0.000210354027844
ko04010	MAPK signaling pathway	39/485	321/7206	0.000342506770905
ko05322	Systemic lupus erythematosus	1/485	151/7206	0.000463233528401
ko04970	Salivary secretion	16/485	95/7206	0.000534821321729
ko03040	Spliceosome	1/485	145/7206	0.00068087196929
ko04745	Phototransduction - fly	9/485	38/7206	0.000737708789324
ko05014	Amyotrophic lateral sclerosis (ALS)	13/485	74/7206	0.00116633925217
ko04360	Axon guidance	29/485	233/7206	0.00120981130331
ko05164	Influenza A	2/485	167/7206	0.0014382587899
ko04730	Long-term depression	13/485	78/7206	0.00192045164085
ko04022	cGMP-PKG signaling pathway	27/485	216/7206	0.00205221832455
ko04744	Phototransduction	8/485	36/7206	0.00224399579263
ko04630	Jak-STAT signaling pathway	1/485	132/7206	0.00224634522213
ko05168	Herpes simplex infection	3/485	182/7206	0.00241965138969
ko05205	Proteoglycans in cancer	7/485	271/7206	0.00286765713705
ko05110	Vibrio cholerae infection	11/485	63/7206	0.00288210372672
ko04260	Cardiac muscle contraction	15/485	98/7206	0.00318297371927
ko04972	Pancreatic secretion	16/485	111/7206	0.00332871212039
ko05166	HTLV-I infection	8/485	292/7206	0.00384540833147
ko04626	Plant-pathogen interaction	5/485	18/7206	0.00556342810475
ko04611	Platelet activation	3/485	163/7206	0.00669498521028
ko04120	Ubiquitin mediated proteolysis	2/485	138/7206	0.00873975315124
ko05120	Epithelial cell signaling in Helicobacter pylori infection	13/485	92/7206	0.00981386154856
ko04014	Ras signaling pathway	30/485	279/7206	0.00995660320126
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/485	79/7206	0.0101042032672
ko04964	Proximal tubule bicarbonate reclamation	6/485	29/7206	0.0113298666825
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/485	14/7206	0.0117946137868
ko04510	Focal adhesion	7/485	240/7206	0.012377810619
ko05161	Hepatitis B	4/485	173/7206	0.0134408365237
ko05010	Alzheimer's disease	23/485	202/7206	0.0142353309467
ko04211	Longevity regulating pathway	2/485	123/7206	0.0169175739217
ko04110	Cell cycle	3/485	145/7206	0.0181074084639
ko03013	RNA transport	4/485	166/7206	0.0183698899232
ko04740	Olfactory transduction	11/485	80/7206	0.0212161402316
ko05169	Epstein-Barr virus infection	6/485	206/7206	0.0231506067201
ko00680	Methane metabolism	6/485	34/7206	0.0241588547699
ko04930	Type II diabetes mellitus	8/485	54/7206	0.0267655386175
ko04925	Aldosterone synthesis and secretion	13/485	105/7206	0.0288065279539
ko04621	NOD-like receptor signaling pathway	4/485	157/7206	0.034407607834
ko04071	Sphingolipid signaling pathway	18/485	162/7206	0.0368894075516
ko04971	Gastric acid secretion	12/485	98/7206	0.0393580085411
ko04060	Cytokine-cytokine receptor interaction	6/485	191/7206	0.0404207614744
ko05418	Fluid shear stress and atherosclerosis	5/485	173/7206	0.0439406423158
ko05034	Alcoholism	24/485	238/7206	0.0468882530935
ko04978	Mineral absorption	6/485	40/7206	0.0492225178438