ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	149/787	423/7206	1.76520642926e-43
ko04724	Glutamatergic synapse	69/787	152/7206	9.0076513463e-28
ko05033	Nicotine addiction	40/787	56/7206	1.03383215332e-26
ko05032	Morphine addiction	52/787	110/7206	3.64448676695e-22
ko04713	Circadian entrainment	56/787	136/7206	3.3887548306e-20
ko04728	Dopaminergic synapse	66/787	185/7206	1.31607135538e-19
ko04727	GABAergic synapse	46/787	110/7206	4.18444710137e-17
ko04723	Retrograde endocannabinoid signaling	60/787	175/7206	5.8552685703e-17
ko04721	Synaptic vesicle cycle	37/787	80/7206	1.02229398005e-15
ko04024	cAMP signaling pathway	76/787	279/7206	1.28106285066e-14
ko04020	Calcium signaling pathway	72/787	265/7206	7.56715512721e-14
ko04726	Serotonergic synapse	47/787	137/7206	1.53031816916e-13
ko04725	Cholinergic synapse	50/787	160/7206	1.50295068351e-12
ko04921	Oxytocin signaling pathway	59/787	209/7206	1.85127949133e-12
ko05031	Amphetamine addiction	35/787	91/7206	4.89012533472e-12
ko04911	Insulin secretion	40/787	117/7206	1.1772849911e-11
ko04720	Long-term potentiation	34/787	99/7206	3.67457639078e-10
ko04261	Adrenergic signaling in cardiomyocytes	52/787	205/7206	3.69430397334e-09
ko04744	Phototransduction	18/787	36/7206	5.45978127223e-09
ko04742	Taste transduction	24/787	61/7206	6.75001498292e-09
ko04970	Salivary secretion	30/787	95/7206	3.68466263126e-08
ko04971	Gastric acid secretion	29/787	98/7206	3.00100893448e-07
ko05030	Cocaine addiction	24/787	73/7206	3.71828145402e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/787	74/7206	4.94441574879e-07
ko04060	Cytokine-cytokine receptor interaction	3/787	191/7206	8.27592446022e-07
ko05164	Influenza A	2/787	167/7206	1.76049160727e-06
ko04925	Aldosterone synthesis and secretion	28/787	105/7206	4.73273954362e-06
ko04730	Long-term depression	23/787	78/7206	5.39570354827e-06
ko05322	Systemic lupus erythematosus	2/787	151/7206	8.09281552077e-06
ko03010	Ribosome	1/787	129/7206	1.03748307381e-05
ko04010	MAPK signaling pathway	61/787	321/7206	1.33393032958e-05
ko05168	Herpes simplex infection	4/787	182/7206	1.68740259566e-05
ko03040	Spliceosome	2/787	145/7206	1.846046704e-05
ko05110	Vibrio cholerae infection	19/787	63/7206	2.4759997404e-05
ko05203	Viral carcinogenesis	11/787	277/7206	3.19939500597e-05
ko04966	Collecting duct acid secretion	11/787	26/7206	4.04750899618e-05
ko04022	cGMP-PKG signaling pathway	43/787	216/7206	8.38247548521e-05
ko04740	Olfactory transduction	21/787	80/7206	9.26801772821e-05
ko05169	Epstein-Barr virus infection	7/787	206/7206	0.000100271540751
ko04745	Phototransduction - fly	13/787	38/7206	0.000114028822427
ko04120	Ubiquitin mediated proteolysis	3/787	138/7206	0.000161910961335
ko04510	Focal adhesion	10/787	240/7206	0.000206443226292
ko05166	HTLV-I infection	14/787	292/7206	0.000245810792394
ko04540	Gap junction	28/787	128/7206	0.000270495172963
ko04626	Plant-pathogen interaction	8/787	18/7206	0.000313946935104
ko04514	Cell adhesion molecules (CAMs)	28/787	130/7206	0.00033228935402
ko04972	Pancreatic secretion	25/787	111/7206	0.00033415058432
ko04630	Jak-STAT signaling pathway	3/787	132/7206	0.00033918660968
ko05215	Prostate cancer	2/787	111/7206	0.000561295271204
ko04922	Glucagon signaling pathway	27/787	128/7206	0.000794061972754
ko04072	Phospholipase D signaling pathway	37/787	197/7206	0.00103069828275
ko05200	Pathways in cancer	33/787	492/7206	0.00124977892976
ko04924	Renin secretion	20/787	86/7206	0.00128687042215
ko04110	Cell cycle	5/787	145/7206	0.00174393719311
ko04750	Inflammatory mediator regulation of TRP channels	25/787	122/7206	0.00177114770091
ko04621	NOD-like receptor signaling pathway	6/787	157/7206	0.00179680854439
ko05161	Hepatitis B	7/787	173/7206	0.00182850939305
ko00010	Glycolysis / Gluconeogenesis	17/787	74/7206	0.00231111413181
ko05140	Leishmaniasis	1/787	75/7206	0.00260980869958
ko01524	Platinum drug resistance	1/787	76/7206	0.0026098810366
ko04612	Antigen processing and presentation	1/787	77/7206	0.00265133267397
ko04260	Cardiac muscle contraction	21/787	98/7206	0.00269412045501
ko05205	Proteoglycans in cancer	15/787	271/7206	0.00271717670067
ko04070	Phosphatidylinositol signaling system	23/787	112/7206	0.00312681947196
ko04550	Signaling pathways regulating pluripotency of stem cells	7/787	165/7206	0.0033735544401
ko03013	RNA transport	7/787	166/7206	0.00342108998457
ko04668	TNF signaling pathway	4/787	120/7206	0.00449138385369
ko05222	Small cell lung cancer	2/787	89/7206	0.00524994014901
ko04141	Protein processing in endoplasmic reticulum	9/787	184/7206	0.00556993881227
ko04064	NF-kappa B signaling pathway	3/787	96/7206	0.0081254813644
ko00680	Methane metabolism	9/787	34/7206	0.00893028744164
ko05202	Transcriptional misregulation in cancer	10/787	188/7206	0.0090287064649
ko04915	Estrogen signaling pathway	24/787	131/7206	0.0102151463158
ko03008	Ribosome biogenesis in eukaryotes	2/787	79/7206	0.0103451463653
ko04014	Ras signaling pathway	44/787	279/7206	0.0107352735611
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/787	59/7206	0.0108718123907
ko04931	Insulin resistance	6/787	137/7206	0.0118575857559
ko04330	Notch signaling pathway	1/787	62/7206	0.0124475581444
ko04114	Oocyte meiosis	25/787	139/7206	0.0124762623441
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/787	14/7206	0.0132320528213
ko04210	Apoptosis	10/787	180/7206	0.0153978287141
ko04350	TGF-beta signaling pathway	4/787	103/7206	0.0163411742621
ko04214	Apoptosis - fly	2/787	72/7206	0.0212107054496
ko05220	Chronic myeloid leukemia	3/787	85/7206	0.0223430972488
ko04657	IL-17 signaling pathway	3/787	87/7206	0.0227709456122
ko05418	Fluid shear stress and atherosclerosis	10/787	173/7206	0.0258688434676
ko05034	Alcoholism	37/787	238/7206	0.0258705270724
ko00280	Valine, leucine and isoleucine degradation	1/787	54/7206	0.0265359377859
ko00520	Amino sugar and nucleotide sugar metabolism	1/787	55/7206	0.0270201410781
ko00480	Glutathione metabolism	1/787	55/7206	0.0270201410781
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/787	92/7206	0.0272782080817
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/787	79/7206	0.0283170190724
ko05010	Alzheimer's disease	32/787	202/7206	0.0290700827887
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/787	182/7206	0.0299766211697
ko05217	Basal cell carcinoma	2/787	68/7206	0.0301106356539
ko05211	Renal cell carcinoma	4/787	96/7206	0.0308795597116
ko04360	Axon guidance	36/787	233/7206	0.0319347340368
ko04371	Apelin signaling pathway	28/787	177/7206	0.0382432373795
ko00590	Arachidonic acid metabolism	1/787	52/7206	0.0402998495449
ko05221	Acute myeloid leukemia	2/787	63/7206	0.0425316046351
ko04610	Complement and coagulation cascades	3/787	79/7206	0.0436908669572
ko04930	Type II diabetes mellitus	11/787	54/7206	0.0437977478735
ko04710	Circadian rhythm	9/787	43/7206	0.0464131793505
ko05224	Breast cancer	11/787	174/7206	0.0486533889961
ko05206	MicroRNAs in cancer	11/787	177/7206	0.0495580537264