ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	99/823	145/7206	2.52848496944e-60
ko05322	Systemic lupus erythematosus	72/823	151/7206	2.17788619315e-29
ko03013	RNA transport	74/823	166/7206	8.10610584107e-28
ko04110	Cell cycle	67/823	145/7206	2.19039410216e-26
ko03440	Homologous recombination	32/823	41/7206	5.1742320482e-23
ko03008	Ribosome biogenesis in eukaryotes	42/823	79/7206	7.3650043482e-20
ko05034	Alcoholism	78/823	238/7206	3.35740907699e-19
ko03030	DNA replication	28/823	38/7206	4.1716457341e-19
ko04111	Cell cycle - yeast	44/823	90/7206	6.9902883673e-19
ko03460	Fanconi anemia pathway	32/823	51/7206	2.30944288404e-18
ko05203	Viral carcinogenesis	81/823	277/7206	1.46836141321e-16
ko04020	Calcium signaling pathway	1/823	265/7206	3.6719827855e-13
ko04113	Meiosis - yeast	32/823	70/7206	4.83533810045e-13
ko00240	Pyrimidine metabolism	40/823	110/7206	5.17918800476e-12
ko03420	Nucleotide excision repair	24/823	46/7206	1.18399305448e-11
ko03430	Mismatch repair	16/823	22/7206	2.81138189528e-11
ko03022	Basal transcription factors	22/823	44/7206	2.55465758394e-10
ko04144	Endocytosis	8/823	342/7206	4.59449942502e-10
ko03015	mRNA surveillance pathway	33/823	93/7206	8.14520951755e-10
ko03018	RNA degradation	30/823	84/7206	4.04250670176e-09
ko03410	Base excision repair	19/823	38/7206	4.35155563344e-09
ko03020	RNA polymerase	16/823	29/7206	1.17305055283e-08
ko05010	Alzheimer's disease	2/823	202/7206	1.37212462736e-08
ko04024	cAMP signaling pathway	7/823	279/7206	4.27091510007e-08
ko04060	Cytokine-cytokine receptor interaction	2/823	191/7206	4.51120379468e-08
ko04151	PI3K-Akt signaling pathway	17/823	390/7206	7.13933212722e-07
ko04022	cGMP-PKG signaling pathway	5/823	216/7206	1.06607578246e-06
ko04723	Retrograde endocannabinoid signaling	3/823	175/7206	1.69687314478e-06
ko04724	Glutamatergic synapse	2/823	152/7206	3.56663863506e-06
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/823	182/7206	5.06023707242e-06
ko00190	Oxidative phosphorylation	1/823	127/7206	6.61580006322e-06
ko04621	NOD-like receptor signaling pathway	3/823	157/7206	1.14464141662e-05
ko04015	Rap1 signaling pathway	11/823	278/7206	1.1918658585e-05
ko04261	Adrenergic signaling in cardiomyocytes	6/823	205/7206	1.6424058731e-05
ko04713	Circadian entrainment	2/823	136/7206	1.66194944032e-05
ko04270	Vascular smooth muscle contraction	3/823	154/7206	1.66733499237e-05
ko05012	Parkinson's disease	3/823	155/7206	1.68360226985e-05
ko04911	Insulin secretion	1/823	117/7206	2.27723798049e-05
ko04921	Oxytocin signaling pathway	7/823	209/7206	3.53783288969e-05
ko04514	Cell adhesion molecules (CAMs)	2/823	130/7206	3.64053651888e-05
ko04725	Cholinergic synapse	4/823	160/7206	4.59052383229e-05
ko05145	Toxoplasmosis	2/823	126/7206	5.32762707452e-05
ko04010	MAPK signaling pathway	16/823	321/7206	6.83716288261e-05
ko04014	Ras signaling pathway	13/823	279/7206	0.000105013492409
ko04810	Regulation of actin cytoskeleton	12/823	264/7206	0.000105965827379
ko04510	Focal adhesion	10/823	240/7206	0.000110865319191
ko04668	TNF signaling pathway	2/823	120/7206	0.0001173031397
ko04611	Platelet activation	5/823	163/7206	0.000157477005542
ko04380	Osteoclast differentiation	3/823	134/7206	0.000159463572497
ko04971	Gastric acid secretion	1/823	98/7206	0.000160593727017
ko04972	Pancreatic secretion	2/823	111/7206	0.000246447612205
ko05414	Dilated cardiomyopathy	2/823	112/7206	0.000247451223217
ko05152	Tuberculosis	7/823	187/7206	0.000260966703689
ko04728	Dopaminergic synapse	7/823	185/7206	0.000370430004061
ko04727	GABAergic synapse	2/823	110/7206	0.000376084779742
ko04924	Renin secretion	1/823	86/7206	0.000525371935642
ko04920	Adipocytokine signaling pathway	1/823	89/7206	0.000559030645841
ko04114	Oocyte meiosis	30/823	139/7206	0.000608124455937
ko04530	Tight junction	11/823	228/7206	0.000653600609684
ko04062	Chemokine signaling pathway	9/823	201/7206	0.000691264487609
ko03450	Non-homologous end-joining	7/823	15/7206	0.000695045244489
ko05410	Hypertrophic cardiomyopathy (HCM)	2/823	100/7206	0.000767831761381
ko04620	Toll-like receptor signaling pathway	2/823	100/7206	0.000767831761381
ko04915	Estrogen signaling pathway	4/823	131/7206	0.000787217631763
ko04218	Cellular senescence	35/823	177/7206	0.00107883195867
ko05142	Chagas disease (American trypanosomiasis)	4/823	130/7206	0.00114379175542
ko04721	Synaptic vesicle cycle	1/823	80/7206	0.00116198258643
ko04976	Bile secretion	1/823	80/7206	0.00116198258643
ko04740	Olfactory transduction	1/823	80/7206	0.00116198258643
ko05169	Epstein-Barr virus infection	39/823	206/7206	0.0011945876626
ko04072	Phospholipase D signaling pathway	9/823	197/7206	0.00130630480588
ko05032	Morphine addiction	3/823	110/7206	0.00138197431954
ko04914	Progesterone-mediated oocyte maturation	23/823	104/7206	0.00157573694902
ko04726	Serotonergic synapse	5/823	137/7206	0.00168997107765
ko04371	Apelin signaling pathway	8/823	177/7206	0.00174913041039
ko00230	Purine metabolism	37/823	194/7206	0.00179245290978
ko05166	HTLV-I infection	51/823	292/7206	0.00181073351316
ko04750	Inflammatory mediator regulation of TRP channels	4/823	122/7206	0.00223522303544
ko05030	Cocaine addiction	1/823	73/7206	0.00255407133894
ko05134	Legionellosis	1/823	74/7206	0.00261036299737
ko05140	Leishmaniasis	1/823	75/7206	0.00271328582614
ko04925	Aldosterone synthesis and secretion	3/823	105/7206	0.00284987092215
ko04659	Th17 cell differentiation	3/823	106/7206	0.00292553088046
ko04360	Axon guidance	13/823	233/7206	0.00315171635736
ko04146	Peroxisome	2/823	89/7206	0.003597808582
ko04120	Ubiquitin mediated proteolysis	27/823	138/7206	0.00428362604514
ko04658	Th1 and Th2 cell differentiation	3/823	96/7206	0.0056357404757
ko05132	Salmonella infection	3/823	98/7206	0.00576619558335
ko00564	Glycerophospholipid metabolism	3/823	99/7206	0.00592988017901
ko04931	Insulin resistance	6/823	137/7206	0.00619625197725
ko04912	GnRH signaling pathway	5/823	122/7206	0.00619633164311
ko04070	Phosphatidylinositol signaling system	4/823	112/7206	0.00625259260936
ko05200	Pathways in cancer	38/823	492/7206	0.00648178779499
ko00561	Glycerolipid metabolism	1/823	63/7206	0.00832614777748
ko04640	Hematopoietic cell lineage	1/823	64/7206	0.00858540662376
ko05202	Transcriptional misregulation in cancer	33/823	188/7206	0.0103406846814
ko04923	Regulation of lipolysis in adipocytes	2/823	77/7206	0.0103500493429
ko01200	Carbon metabolism	6/823	128/7206	0.011320386245
ko04922	Glucagon signaling pathway	6/823	128/7206	0.011320386245
ko05031	Amphetamine addiction	3/823	91/7206	0.0115453816198
ko03060	Protein export	7/823	23/7206	0.0116954763631
ko05168	Herpes simplex infection	32/823	182/7206	0.0125618372814
ko04142	Lysosome	8/823	151/7206	0.0135699481367
ko04670	Leukocyte transendothelial migration	8/823	151/7206	0.0135699481367
ko00010	Glycolysis / Gluconeogenesis	2/823	74/7206	0.0150613107265
ko05133	Pertussis	3/823	87/7206	0.0160781290453
ko04152	AMPK signaling pathway	9/823	161/7206	0.0166094244832
ko04930	Type II diabetes mellitus	1/823	54/7206	0.0177445095334
ko05205	Proteoglycans in cancer	19/823	271/7206	0.0190547157952
ko04933	AGE-RAGE signaling pathway in diabetic complications	7/823	135/7206	0.0193764515443
ko04066	HIF-1 signaling pathway	6/823	123/7206	0.0209065667499
ko04138	Autophagy - yeast	3/823	81/7206	0.0220106355425
ko04115	p53 signaling pathway	15/823	74/7206	0.0252930161553
ko04630	Jak-STAT signaling pathway	7/823	132/7206	0.0259037426571
ko05160	Hepatitis C	9/823	153/7206	0.0282076496225
ko05130	Pathogenic Escherichia coli infection	3/823	77/7206	0.0306940388499
ko04512	ECM-receptor interaction	3/823	79/7206	0.0309897799122
ko04540	Gap junction	7/823	128/7206	0.0341038916028
ko04712	Circadian rhythm - plant	3/823	7/7206	0.0364962798152
ko04910	Insulin signaling pathway	11/823	172/7206	0.0381372496304
ko05204	Chemical carcinogenesis	1/823	48/7206	0.0382543631124
ko00260	Glycine, serine and threonine metabolism	1/823	48/7206	0.0382543631124
ko05418	Fluid shear stress and atherosclerosis	11/823	173/7206	0.0385095838287
ko00510	N-Glycan biosynthesis	1/823	50/7206	0.0401566979865
ko04662	B cell receptor signaling pathway	4/823	88/7206	0.0415370321319
ko00562	Inositol phosphate metabolism	4/823	89/7206	0.0420424144663
ko01212	Fatty acid metabolism	2/823	60/7206	0.04204272984
ko04622	RIG-I-like receptor signaling pathway	2/823	62/7206	0.042452470022
ko04660	T cell receptor signaling pathway	7/823	124/7206	0.0447132681244