ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	57/451	152/7206	1.19025284531e-30
ko05033	Nicotine addiction	36/451	56/7206	3.01612134386e-30
ko04080	Neuroactive ligand-receptor interaction	89/451	423/7206	4.09300530269e-26
ko04727	GABAergic synapse	36/451	110/7206	2.13779492551e-17
ko04723	Retrograde endocannabinoid signaling	43/451	175/7206	2.09058108075e-15
ko04728	Dopaminergic synapse	43/451	185/7206	1.77899555023e-14
ko04024	cAMP signaling pathway	54/451	279/7206	2.66151534816e-14
ko05032	Morphine addiction	32/451	110/7206	5.94469189808e-14
ko04713	Circadian entrainment	33/451	136/7206	6.43718873921e-12
ko04911	Insulin secretion	29/451	117/7206	7.32173266841e-11
ko04721	Synaptic vesicle cycle	23/451	80/7206	2.91610628679e-10
ko04725	Cholinergic synapse	32/451	160/7206	2.75096125696e-09
ko05031	Amphetamine addiction	23/451	91/7206	4.71275470391e-09
ko04514	Cell adhesion molecules (CAMs)	27/451	130/7206	2.13917133667e-08
ko05030	Cocaine addiction	19/451	73/7206	6.32205872315e-08
ko04020	Calcium signaling pathway	41/451	265/7206	7.07212670658e-08
ko04720	Long-term potentiation	22/451	99/7206	1.26137442572e-07
ko04726	Serotonergic synapse	26/451	137/7206	2.64569502723e-07
ko04742	Taste transduction	16/451	61/7206	6.28002344855e-07
ko04010	MAPK signaling pathway	44/451	321/7206	6.73146506868e-07
ko04261	Adrenergic signaling in cardiomyocytes	32/451	205/7206	1.17278001932e-06
ko04072	Phospholipase D signaling pathway	31/451	197/7206	1.44957842126e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	17/451	74/7206	2.12151505869e-06
ko04921	Oxytocin signaling pathway	31/451	209/7206	6.30678625138e-06
ko04970	Salivary secretion	17/451	95/7206	6.97151976215e-05
ko04925	Aldosterone synthesis and secretion	18/451	105/7206	7.71179033197e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/451	79/7206	0.000334652478794
ko04360	Axon guidance	29/451	233/7206	0.000455893397632
ko04730	Long-term depression	13/451	78/7206	0.000991278014961
ko03040	Spliceosome	1/451	145/7206	0.00149575941201
ko04930	Type II diabetes mellitus	10/451	54/7206	0.0016516047037
ko04972	Pancreatic secretion	16/451	111/7206	0.00211068126054
ko05203	Viral carcinogenesis	6/451	277/7206	0.00215558093297
ko04022	cGMP-PKG signaling pathway	25/451	216/7206	0.00247487858317
ko03013	RNA transport	2/451	166/7206	0.00298107123229
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/451	59/7206	0.00327675616911
ko04060	Cytokine-cytokine receptor interaction	3/451	191/7206	0.00350525240827
ko04260	Cardiac muscle contraction	14/451	98/7206	0.00464840286422
ko04971	Gastric acid secretion	14/451	98/7206	0.00464840286422
ko05414	Dilated cardiomyopathy	15/451	112/7206	0.00468229160841
ko00190	Oxidative phosphorylation	1/451	127/7206	0.00470354722491
ko04915	Estrogen signaling pathway	17/451	131/7206	0.00508620340459
ko05205	Proteoglycans in cancer	7/451	271/7206	0.00702982334046
ko04964	Proximal tubule bicarbonate reclamation	6/451	29/7206	0.00804081488915
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/451	14/7206	0.00916071952325
ko02024	Quorum sensing	4/451	15/7206	0.0118851412868
ko04145	Phagosome	3/451	162/7206	0.0131785082833
ko05164	Influenza A	3/451	167/7206	0.0137818201848
ko00240	Pyrimidine metabolism	1/451	110/7206	0.0149209776379
ko04540	Gap junction	15/451	128/7206	0.0158167183319
ko04621	NOD-like receptor signaling pathway	3/451	157/7206	0.0184057974322
ko05168	Herpes simplex infection	4/451	182/7206	0.0187830939014
ko04071	Sphingolipid signaling pathway	18/451	162/7206	0.0196325342809
ko04350	TGF-beta signaling pathway	1/451	103/7206	0.0213805168354
ko04015	Rap1 signaling pathway	27/451	278/7206	0.0220580476261
ko04014	Ras signaling pathway	27/451	279/7206	0.0224179163583
ko01200	Carbon metabolism	2/451	128/7206	0.0247007978141
ko04142	Lysosome	3/451	151/7206	0.0255563034305
ko05322	Systemic lupus erythematosus	3/451	151/7206	0.0255563034305
ko04962	Vasopressin-regulated water reabsorption	8/451	58/7206	0.0268985567851
ko05231	Choline metabolism in cancer	15/451	134/7206	0.0280678545845
ko05162	Measles	2/451	120/7206	0.0341579781669
ko04110	Cell cycle	3/451	145/7206	0.0353816215603
ko04960	Aldosterone-regulated sodium reabsorption	6/451	41/7206	0.0405567170176
ko04973	Carbohydrate digestion and absorption	6/451	42/7206	0.0449222569785
ko04940	Type I diabetes mellitus	5/451	32/7206	0.0466837079299
ko04120	Ubiquitin mediated proteolysis	3/451	138/7206	0.0483691076677