ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	53/851	80/7206	1.04425165325e-30
ko04080	Neuroactive ligand-receptor interaction	129/851	423/7206	1.17083316422e-26
ko04724	Glutamatergic synapse	65/851	152/7206	1.78995002706e-22
ko05033	Nicotine addiction	37/851	56/7206	1.06887240543e-21
ko04728	Dopaminergic synapse	66/851	185/7206	8.76399510414e-18
ko04727	GABAergic synapse	45/851	110/7206	5.03452159461e-15
ko05032	Morphine addiction	45/851	110/7206	5.03452159461e-15
ko04713	Circadian entrainment	51/851	136/7206	5.20151795237e-15
ko04723	Retrograde endocannabinoid signaling	57/851	175/7206	1.56932817434e-13
ko04725	Cholinergic synapse	50/851	160/7206	2.87755795251e-11
ko04966	Collecting duct acid secretion	17/851	26/7206	1.61455215749e-10
ko04911	Insulin secretion	39/851	117/7206	5.50553370856e-10
ko05031	Amphetamine addiction	33/851	91/7206	1.01885501207e-09
ko04024	cAMP signaling pathway	68/851	279/7206	2.15384047046e-09
ko04261	Adrenergic signaling in cardiomyocytes	52/851	205/7206	5.88271183232e-08
ko04726	Serotonergic synapse	38/851	137/7206	2.74075055564e-07
ko03040	Spliceosome	1/851	145/7206	3.48452747355e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/851	74/7206	5.30985844087e-07
ko04720	Long-term potentiation	30/851	99/7206	5.86612944178e-07
ko04921	Oxytocin signaling pathway	50/851	209/7206	6.12120200007e-07
ko05110	Vibrio cholerae infection	22/851	63/7206	1.34823027394e-06
ko05203	Viral carcinogenesis	10/851	277/7206	1.50471335499e-06
ko05030	Cocaine addiction	24/851	73/7206	1.5672279022e-06
ko04514	Cell adhesion molecules (CAMs)	35/851	130/7206	1.64744643497e-06
ko04742	Taste transduction	21/851	61/7206	3.05005928622e-06
ko04360	Axon guidance	52/851	233/7206	3.95051081397e-06
ko04744	Phototransduction	15/851	36/7206	5.41477010313e-06
ko04060	Cytokine-cytokine receptor interaction	5/851	191/7206	6.3205360785e-06
ko04120	Ubiquitin mediated proteolysis	2/851	138/7206	7.36113196647e-06
ko04970	Salivary secretion	27/851	95/7206	8.25574771455e-06
ko05168	Herpes simplex infection	5/851	182/7206	1.2899718561e-05
ko05120	Epithelial cell signaling in Helicobacter pylori infection	25/851	92/7206	4.97750833306e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/851	14/7206	5.71974704464e-05
ko03013	RNA transport	5/851	166/7206	7.66565090605e-05
ko05164	Influenza A	5/851	167/7206	7.81929902739e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/851	59/7206	9.6220569861e-05
ko04020	Calcium signaling pathway	52/851	265/7206	0.000197438322803
ko04145	Phagosome	35/851	162/7206	0.000304199959621
ko04924	Renin secretion	22/851	86/7206	0.000321773882597
ko04971	Gastric acid secretion	24/851	98/7206	0.000392549956009
ko05162	Measles	3/851	120/7206	0.000477645836497
ko04621	NOD-like receptor signaling pathway	6/851	157/7206	0.000648145615933
ko04141	Protein processing in endoplasmic reticulum	8/851	184/7206	0.000689696545465
ko04010	MAPK signaling pathway	58/851	321/7206	0.000733070510013
ko04745	Phototransduction - fly	12/851	38/7206	0.000988812456676
ko04612	Antigen processing and presentation	1/851	77/7206	0.00113269434793
ko04925	Aldosterone synthesis and secretion	24/851	105/7206	0.00116854478955
ko03008	Ribosome biogenesis in eukaryotes	1/851	79/7206	0.00118851338008
ko04540	Gap junction	28/851	128/7206	0.00122363879476
ko05322	Systemic lupus erythematosus	6/851	151/7206	0.0012601513634
ko05323	Rheumatoid arthritis	21/851	89/7206	0.00145883006822
ko05161	Hepatitis B	8/851	173/7206	0.0017371430341
ko04022	cGMP-PKG signaling pathway	41/851	216/7206	0.00177911363464
ko04626	Plant-pathogen interaction	7/851	18/7206	0.00306749089027
ko04140	Autophagy - animal	8/851	164/7206	0.00313757801108
ko04064	NF-kappa B signaling pathway	3/851	96/7206	0.00391357201787
ko04730	Long-term depression	18/851	78/7206	0.00421315079966
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/851	79/7206	0.00471041075218
ko04964	Proximal tubule bicarbonate reclamation	9/851	29/7206	0.00478392770825
ko00190	Oxidative phosphorylation	26/851	127/7206	0.00493741308942
ko05205	Proteoglycans in cancer	18/851	271/7206	0.00528056260759
ko05166	HTLV-I infection	20/851	292/7206	0.00539850004659
ko00561	Glycerolipid metabolism	1/851	63/7206	0.00545943612328
ko04630	Jak-STAT signaling pathway	6/851	132/7206	0.00607521186845
ko04260	Cardiac muscle contraction	21/851	98/7206	0.00646962363139
ko04972	Pancreatic secretion	23/851	111/7206	0.00683551110571
ko04740	Olfactory transduction	18/851	80/7206	0.00763820690776
ko04146	Peroxisome	3/851	89/7206	0.00784327313745
ko05146	Amoebiasis	4/851	99/7206	0.0114865074485
ko04976	Bile secretion	17/851	80/7206	0.0137104965912
ko04668	TNF signaling pathway	6/851	120/7206	0.0150770912182
ko00240	Pyrimidine metabolism	5/851	110/7206	0.0160086784427
ko04950	Maturity onset diabetes of the young	8/851	29/7206	0.0162709425822
ko05206	MicroRNAs in cancer	11/851	177/7206	0.0177731660263
ko00520	Amino sugar and nucleotide sugar metabolism	1/851	55/7206	0.0183035128545
ko00480	Glutathione metabolism	1/851	55/7206	0.0183035128545
ko05169	Epstein-Barr virus infection	14/851	206/7206	0.0211615283206
ko04962	Vasopressin-regulated water reabsorption	13/851	58/7206	0.0216744284707
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/851	15/7206	0.0247438758754
ko05414	Dilated cardiomyopathy	21/851	112/7206	0.026749980413
ko00590	Arachidonic acid metabolism	1/851	52/7206	0.0273484205812
ko04915	Estrogen signaling pathway	24/851	131/7206	0.0276436394008
ko04350	TGF-beta signaling pathway	5/851	103/7206	0.0295625407451
ko04640	Hematopoietic cell lineage	2/851	64/7206	0.0298641899197
ko05140	Leishmaniasis	3/851	75/7206	0.0303331864632
ko01524	Platinum drug resistance	3/851	76/7206	0.0305021316151
ko04933	AGE-RAGE signaling pathway in diabetic complications	8/851	135/7206	0.030596657619
ko04114	Oocyte meiosis	25/851	139/7206	0.0323839836357
ko04210	Apoptosis	12/851	180/7206	0.0341962502864
ko05010	Alzheimer's disease	34/851	202/7206	0.0346739215824
ko04110	Cell cycle	9/851	145/7206	0.0364165877393
ko05215	Prostate cancer	6/851	111/7206	0.0365341979129
ko00620	Pyruvate metabolism	1/851	46/7206	0.0377176233879
ko03420	Nucleotide excision repair	1/851	46/7206	0.0377176233879
ko00260	Glycine, serine and threonine metabolism	1/851	48/7206	0.0392429960162
ko05219	Bladder cancer	1/851	48/7206	0.0392429960162
ko05220	Chronic myeloid leukemia	4/851	85/7206	0.0410964511267
ko04214	Apoptosis - fly	3/851	72/7206	0.0422320031894
ko04014	Ras signaling pathway	44/851	279/7206	0.0461973857625
ko04391	Hippo signaling pathway - fly	17/851	90/7206	0.0467592630431
ko04611	Platelet activation	11/851	163/7206	0.0482817613906