ko pathway ratio_in_study ratio_in_pop p_value ko04137 Mitophagy - animal 20/405 82/7206 1.52235637126e-08 ko04380 Osteoclast differentiation 25/405 134/7206 8.04174528235e-08 ko04621 NOD-like receptor signaling pathway 24/405 157/7206 6.14238073709e-06 ko05340 Primary immunodeficiency 9/405 30/7206 2.54408295521e-05 ko04060 Cytokine-cytokine receptor interaction 26/405 191/7206 3.520670184e-05 ko05164 Influenza A 23/405 167/7206 5.35265081069e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 25/405 191/7206 7.40170813499e-05 ko04668 TNF signaling pathway 18/405 120/7206 0.000115194209148 ko05152 Tuberculosis 24/405 187/7206 0.000133174134434 ko04068 FoxO signaling pathway 22/405 167/7206 0.000208260721825 ko05321 Inflammatory bowel disease (IBD) 11/405 56/7206 0.000231253274522 ko05140 Leishmaniasis 13/405 75/7206 0.000239537962764 ko04650 Natural killer cell mediated cytotoxicity 15/405 97/7206 0.00030153096658 ko04630 Jak-STAT signaling pathway 18/405 132/7206 0.000390338503783 ko00051 Fructose and mannose metabolism 9/405 42/7206 0.000434355125571 ko04064 NF-kappa B signaling pathway 14/405 96/7206 0.00087103723033 ko05162 Measles 16/405 120/7206 0.00104019760282 ko04217 Necroptosis 21/405 178/7206 0.00130563777398 ko05168 Herpes simplex infection 21/405 182/7206 0.00155402298958 ko04670 Leukocyte transendothelial migration 18/405 151/7206 0.00207152430345 ko04710 Circadian rhythm 8/405 43/7206 0.00236963638706 ko05145 Toxoplasmosis 16/405 126/7206 0.00239589089029 ko00592 alpha-Linolenic acid metabolism 5/405 19/7206 0.00330006210143 ko05150 Staphylococcus aureus infection 7/405 36/7206 0.0033947113387 ko04620 Toll-like receptor signaling pathway 13/405 100/7206 0.00375667576963 ko05034 Alcoholism 4/405 238/7206 0.00383671765905 ko00120 Primary bile acid biosynthesis 5/405 20/7206 0.00420029243597 ko04610 Complement and coagulation cascades 11/405 79/7206 0.00439170140719 ko04145 Phagosome 18/405 162/7206 0.00499735514736 ko03040 Spliceosome 1/405 145/7206 0.0050870017664 ko04611 Platelet activation 18/405 163/7206 0.0052359087081 ko04136 Autophagy - other 6/405 31/7206 0.00673712796225 ko04659 Th17 cell differentiation 13/405 106/7206 0.00827554529115 ko03013 RNA transport 2/405 166/7206 0.00912504124139 ko05166 HTLV-I infection 27/405 292/7206 0.00918432933232 ko04066 HIF-1 signaling pathway 14/405 123/7206 0.00961779677832 ko03010 Ribosome 1/405 129/7206 0.0103719049401 ko04664 Fc epsilon RI signaling pathway 10/405 77/7206 0.0105304456989 ko05418 Fluid shear stress and atherosclerosis 18/405 173/7206 0.0108926109771 ko04658 Th1 and Th2 cell differentiation 12/405 96/7206 0.0109537308919 ko05144 Malaria 7/405 45/7206 0.0119576934157 ko04933 AGE-RAGE signaling pathway in diabetic complications 15/405 135/7206 0.0119990168016 ko00710 Carbon fixation in photosynthetic organisms 5/405 27/7206 0.0158303731415 ko04672 Intestinal immune network for IgA production 6/405 37/7206 0.0160252221622 ko04110 Cell cycle 2/405 145/7206 0.0172617778933 ko04723 Retrograde endocannabinoid signaling 3/405 175/7206 0.0186728464139 ko04622 RIG-I-like receptor signaling pathway 8/405 62/7206 0.0218744478499 ko04666 Fc gamma R-mediated phagocytosis 13/405 122/7206 0.025878087287 ko05161 Hepatitis B 17/405 173/7206 0.0273964884716 ko04662 B cell receptor signaling pathway 10/405 88/7206 0.0311167813284 ko05323 Rheumatoid arthritis 10/405 89/7206 0.0326003670342 ko04015 Rap1 signaling pathway 24/405 278/7206 0.0327950019324 ko00052 Galactose metabolism 5/405 33/7206 0.035383037797 ko00071 Fatty acid degradation 6/405 45/7206 0.0386228304389 ko04612 Antigen processing and presentation 9/405 77/7206 0.0392373758325 ko04072 Phospholipase D signaling pathway 18/405 197/7206 0.0396188612111 ko00362 Benzoate degradation 2/405 6/7206 0.0406494710338 ko00220 Arginine biosynthesis 4/405 24/7206 0.0427611106167 ko04138 Autophagy - yeast 9/405 81/7206 0.0461022806724 ko01040 Biosynthesis of unsaturated fatty acids 4/405 25/7206 0.048730464518 ko04540 Gap junction 2/405 128/7206 0.0491705907254