ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 12/98 152/7206 8.56297811371e-07 ko05033 Nicotine addiction 7/98 56/7206 9.3281439198e-06 ko04080 Neuroactive ligand-receptor interaction 18/98 423/7206 1.25013742927e-05 ko04727 GABAergic synapse 8/98 110/7206 0.000114979681821 ko05032 Morphine addiction 8/98 110/7206 0.000114979681821 ko04723 Retrograde endocannabinoid signaling 10/98 175/7206 0.000121925668796 ko04728 Dopaminergic synapse 10/98 185/7206 0.000192755443485 ko05014 Amyotrophic lateral sclerosis (ALS) 6/98 74/7206 0.000476671649266 ko04713 Circadian entrainment 8/98 136/7206 0.000494485083111 ko00350 Tyrosine metabolism 4/98 33/7206 0.00097261084037 ko04514 Cell adhesion molecules (CAMs) 7/98 130/7206 0.00187563464162 ko04726 Serotonergic synapse 7/98 137/7206 0.00252838239306 ko04670 Leukocyte transendothelial migration 7/98 151/7206 0.00434696404092 ko04024 cAMP signaling pathway 10/98 279/7206 0.00445353120069 ko04740 Olfactory transduction 5/98 80/7206 0.0045136863882 ko04725 Cholinergic synapse 7/98 160/7206 0.00595378722075 ko04961 Endocrine and other factor-regulated calcium reabsorption 4/98 59/7206 0.00826697064074 ko04974 Protein digestion and absorption 5/98 96/7206 0.00968378612664 ko04916 Melanogenesis 6/98 142/7206 0.0125864469486 ko05030 Cocaine addiction 4/98 73/7206 0.0171248763932 ko04972 Pancreatic secretion 5/98 111/7206 0.0173280968539 ko00830 Retinol metabolism 3/98 42/7206 0.01908938667 ko04730 Long-term depression 4/98 78/7206 0.0213247273872 ko04512 ECM-receptor interaction 4/98 79/7206 0.0222339477744 ko01051 Biosynthesis of ansamycins 1/98 2/7206 0.0270164638422 ko05031 Amphetamine addiction 4/98 91/7206 0.0350031127881 ko04970 Salivary secretion 4/98 95/7206 0.0400364733944 ko04151 PI3K-Akt signaling pathway 10/98 390/7206 0.0426617630378 ko05034 Alcoholism 7/98 238/7206 0.0428409515972 ko04260 Cardiac muscle contraction 4/98 98/7206 0.0440691997606