ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 18/177 191/7206 8.68893580127e-07 ko04657 IL-17 signaling pathway 11/177 87/7206 7.968178194e-06 ko04072 Phospholipase D signaling pathway 15/177 197/7206 9.26257497066e-05 ko04380 Osteoclast differentiation 12/177 134/7206 0.000103238170863 ko04662 B cell receptor signaling pathway 9/177 88/7206 0.000286142755182 ko04014 Ras signaling pathway 17/177 279/7206 0.000472047678134 ko04668 TNF signaling pathway 10/177 120/7206 0.000697402696446 ko05215 Prostate cancer 9/177 111/7206 0.00156203486276 ko04621 NOD-like receptor signaling pathway 11/177 157/7206 0.0016086796005 ko05231 Choline metabolism in cancer 10/177 134/7206 0.00163097637346 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/177 135/7206 0.00172474767139 ko04725 Cholinergic synapse 11/177 160/7206 0.0018720175128 ko04658 Th1 and Th2 cell differentiation 8/177 96/7206 0.00238189607944 ko04064 NF-kappa B signaling pathway 8/177 96/7206 0.00238189607944 ko05164 Influenza A 11/177 167/7206 0.00262497595104 ko04750 Inflammatory mediator regulation of TRP channels 9/177 122/7206 0.00299563276827 ko05161 Hepatitis B 11/177 173/7206 0.00345042416372 ko04062 Chemokine signaling pathway 12/177 201/7206 0.00382825391815 ko05160 Hepatitis C 10/177 153/7206 0.0043028557417 ko04024 cAMP signaling pathway 15/177 279/7206 0.00433096777325 ko05031 Amphetamine addiction 7/177 91/7206 0.00684907438789 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/177 191/7206 0.00723424436574 ko04068 FoxO signaling pathway 10/177 167/7206 0.00790098034661 ko04916 Melanogenesis 9/177 142/7206 0.00808547648522 ko04650 Natural killer cell mediated cytotoxicity 7/177 97/7206 0.00961986344973 ko04666 Fc gamma R-mediated phagocytosis 8/177 122/7206 0.0101089641501 ko00564 Glycerophospholipid metabolism 7/177 99/7206 0.0107037317644 ko04659 Th17 cell differentiation 7/177 106/7206 0.0152005928273 ko04960 Aldosterone-regulated sodium reabsorption 4/177 41/7206 0.0175620143603 ko00140 Steroid hormone biosynthesis 4/177 41/7206 0.0175620143603 ko04931 Insulin resistance 8/177 137/7206 0.0192842356723 ko04917 Prolactin signaling pathway 6/177 87/7206 0.0197635902229 ko04070 Phosphatidylinositol signaling system 7/177 112/7206 0.020011377816 ko04919 Thyroid hormone signaling pathway 8/177 143/7206 0.0242479044665 ko00966 Glucosinolate biosynthesis 1/177 1/7206 0.0245628642798 ko04911 Insulin secretion 7/177 117/7206 0.0247624424325 ko05202 Transcriptional misregulation in cancer 10/177 188/7206 0.0259392119506 ko04912 GnRH signaling pathway 7/177 122/7206 0.0302373269144 ko04211 Longevity regulating pathway 7/177 123/7206 0.0314228208168 ko04066 HIF-1 signaling pathway 7/177 123/7206 0.0314228208168 ko05030 Cocaine addiction 5/177 73/7206 0.0331674071405 ko04724 Glutamatergic synapse 8/177 152/7206 0.0332799358355 ko04620 Toll-like receptor signaling pathway 6/177 100/7206 0.0360491345964 ko04922 Glucagon signaling pathway 7/177 128/7206 0.0378190515036 ko04020 Calcium signaling pathway 12/177 265/7206 0.0392992388559 ko04930 Type II diabetes mellitus 4/177 54/7206 0.042984634489 ko04630 Jak-STAT signaling pathway 7/177 132/7206 0.0435138531266 ko04925 Aldosterone synthesis and secretion 6/177 105/7206 0.0440946089539 ko05214 Glioma 5/177 79/7206 0.0443249573447 ko04015 Rap1 signaling pathway 12/177 278/7206 0.0478124716675 ko05200 Pathways in cancer 19/177 492/7206 0.0479140863128 ko05321 Inflammatory bowel disease (IBD) 4/177 56/7206 0.0480977544209 ko05230 Central carbon metabolism in cancer 5/177 81/7206 0.0484878785844 ko00254 Aflatoxin biosynthesis 1/177 2/7206 0.0485257196616 ko04080 Neuroactive ligand-receptor interaction 17/177 423/7206 0.049183023377 ko00760 Nicotinate and nicotinamide metabolism 3/177 34/7206 0.0499845137748