ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	38/723	56/7206	1.69843644737e-25
ko04080	Neuroactive ligand-receptor interaction	115/723	423/7206	2.4366888902e-25
ko04724	Glutamatergic synapse	60/723	152/7206	2.28852548146e-22
ko04727	GABAergic synapse	46/723	110/7206	1.39297170886e-18
ko05032	Morphine addiction	45/723	110/7206	9.3941663165e-18
ko04721	Synaptic vesicle cycle	37/723	80/7206	6.20484356963e-17
ko04728	Dopaminergic synapse	57/723	185/7206	1.74219777193e-15
ko04713	Circadian entrainment	46/723	136/7206	2.15872618997e-14
ko04723	Retrograde endocannabinoid signaling	53/723	175/7206	3.94301412934e-14
ko04725	Cholinergic synapse	49/723	160/7206	2.34553542325e-13
ko04024	cAMP signaling pathway	67/723	279/7206	3.66465809761e-12
ko04744	Phototransduction	19/723	36/7206	1.40674778291e-10
ko04911	Insulin secretion	33/723	117/7206	2.07562367282e-08
ko04514	Cell adhesion molecules (CAMs)	35/723	130/7206	2.8705306627e-08
ko05030	Cocaine addiction	24/723	73/7206	7.45907155166e-08
ko04726	Serotonergic synapse	35/723	137/7206	1.20238225736e-07
ko05031	Amphetamine addiction	27/723	91/7206	1.29147173953e-07
ko04261	Adrenergic signaling in cardiomyocytes	45/723	205/7206	3.38055181918e-07
ko04742	Taste transduction	20/723	61/7206	9.62762895114e-07
ko04970	Salivary secretion	26/723	95/7206	1.25194723636e-06
ko05203	Viral carcinogenesis	7/723	277/7206	1.81418369535e-06
ko04921	Oxytocin signaling pathway	43/723	209/7206	3.42627879379e-06
ko05164	Influenza A	2/723	167/7206	5.85611991624e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	21/723	74/7206	7.07424552127e-06
ko03040	Spliceosome	1/723	145/7206	7.79802798761e-06
ko04020	Calcium signaling pathway	50/723	265/7206	8.81753956696e-06
ko04060	Cytokine-cytokine receptor interaction	4/723	191/7206	2.47051748942e-05
ko05322	Systemic lupus erythematosus	2/723	151/7206	2.75097301277e-05
ko04010	MAPK signaling pathway	55/723	321/7206	5.63368538515e-05
ko04964	Proximal tubule bicarbonate reclamation	11/723	29/7206	6.10678403714e-05
ko05162	Measles	1/723	120/7206	8.15567564656e-05
ko04976	Bile secretion	20/723	80/7206	8.65042547082e-05
ko04120	Ubiquitin mediated proteolysis	2/723	138/7206	8.67805849263e-05
ko05205	Proteoglycans in cancer	10/723	271/7206	0.000117358790717
ko04720	Long-term potentiation	22/723	99/7206	0.000278246902267
ko04022	cGMP-PKG signaling pathway	39/723	216/7206	0.000300510535807
ko04972	Pancreatic secretion	24/723	111/7206	0.000307975655161
ko04978	Mineral absorption	12/723	40/7206	0.000375213403494
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/723	59/7206	0.000535890589884
ko04966	Collecting duct acid secretion	9/723	26/7206	0.000635615731323
ko04141	Protein processing in endoplasmic reticulum	6/723	184/7206	0.00071374460961
ko04260	Cardiac muscle contraction	21/723	98/7206	0.00093598248208
ko03013	RNA transport	5/723	166/7206	0.000939595232666
ko05168	Herpes simplex infection	6/723	182/7206	0.001002315353
ko04360	Axon guidance	39/723	233/7206	0.0011956685051
ko05166	HTLV-I infection	14/723	292/7206	0.00136440192794
ko05169	Epstein-Barr virus infection	8/723	206/7206	0.00137698867665
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/723	14/7206	0.00147996623311
ko04730	Long-term depression	17/723	78/7206	0.00180119289118
ko04621	NOD-like receptor signaling pathway	5/723	157/7206	0.00180821097905
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/723	79/7206	0.00202134322148
ko05016	Huntington's disease	9/723	215/7206	0.0024814908954
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/723	182/7206	0.00256249379215
ko04924	Renin secretion	18/723	86/7206	0.00299798189581
ko04217	Necroptosis	7/723	178/7206	0.00347206335023
ko03008	Ribosome biogenesis in eukaryotes	1/723	79/7206	0.00402506377546
ko01200	Carbon metabolism	4/723	128/7206	0.00459293541281
ko04971	Gastric acid secretion	19/723	98/7206	0.00568030728318
ko04014	Ras signaling pathway	42/723	279/7206	0.00783301267862
ko00310	Lysine degradation	1/723	73/7206	0.00912550259297
ko05110	Vibrio cholerae infection	13/723	63/7206	0.00987406593204
ko05220	Chronic myeloid leukemia	2/723	85/7206	0.0106891941319
ko04630	Jak-STAT signaling pathway	5/723	132/7206	0.0122252623853
ko04925	Aldosterone synthesis and secretion	19/723	105/7206	0.0125992911282
ko05161	Hepatitis B	8/723	173/7206	0.0142513603195
ko03018	RNA degradation	2/723	84/7206	0.0157041995095
ko04110	Cell cycle	6/723	145/7206	0.0164458753962
ko00564	Glycerophospholipid metabolism	3/723	99/7206	0.0168184681788
ko00561	Glycerolipid metabolism	1/723	63/7206	0.0186809025316
ko04612	Antigen processing and presentation	2/723	77/7206	0.0216802811018
ko04610	Complement and coagulation cascades	2/723	79/7206	0.0219671235012
ko05215	Prostate cancer	4/723	111/7206	0.0239566726363
ko04611	Platelet activation	8/723	163/7206	0.024470373339
ko04140	Autophagy - animal	8/723	164/7206	0.0245717886798
ko00330	Arginine and proline metabolism	1/723	61/7206	0.0286182066432
ko05140	Leishmaniasis	2/723	75/7206	0.0312181896215
ko05414	Dilated cardiomyopathy	18/723	112/7206	0.0387409785322
ko00480	Glutathione metabolism	1/723	55/7206	0.039841761575
ko04371	Apelin signaling pathway	26/723	177/7206	0.0423585805815
ko04214	Apoptosis - fly	2/723	72/7206	0.0451019047447
ko04071	Sphingolipid signaling pathway	24/723	162/7206	0.0467456118018
ko05034	Alcoholism	33/723	238/7206	0.0485251225084
ko04068	FoxO signaling pathway	9/723	167/7206	0.0491394494655