ko pathway ratio_in_study ratio_in_pop p_value ko04966 Collecting duct acid secretion 9/320 26/7206 9.60739515376e-07 ko04626 Plant-pathogen interaction 7/320 18/7206 6.64837420562e-06 ko04070 Phosphatidylinositol signaling system 17/320 112/7206 7.63619058131e-06 ko04138 Autophagy - yeast 14/320 81/7206 1.07016392676e-05 ko04725 Cholinergic synapse 20/320 160/7206 2.429600977e-05 ko04727 GABAergic synapse 16/320 110/7206 2.45483191185e-05 ko04713 Circadian entrainment 18/320 136/7206 2.86719804931e-05 ko04745 Phototransduction - fly 9/320 38/7206 3.1246302417e-05 ko04724 Glutamatergic synapse 19/320 152/7206 3.88519741873e-05 ko04136 Autophagy - other 8/320 31/7206 4.46004171512e-05 ko04137 Mitophagy - animal 13/320 82/7206 5.71026007628e-05 ko04728 Dopaminergic synapse 21/320 185/7206 6.52793721725e-05 ko05110 Vibrio cholerae infection 11/320 63/7206 8.64446910155e-05 ko04721 Synaptic vesicle cycle 12/320 80/7206 0.000189685070824 ko04720 Long-term potentiation 13/320 99/7206 0.000401066096067 ko00190 Oxidative phosphorylation 15/320 127/7206 0.000472333098145 ko04710 Circadian rhythm 8/320 43/7206 0.000514647677626 ko04911 Insulin secretion 14/320 117/7206 0.00063576974346 ko05120 Epithelial cell signaling in Helicobacter pylori infection 12/320 92/7206 0.000708642205789 ko04024 cAMP signaling pathway 25/320 279/7206 0.000857303684729 ko04744 Phototransduction 7/320 36/7206 0.00087429782486 ko04921 Oxytocin signaling pathway 20/320 209/7206 0.00100599951853 ko05032 Morphine addiction 13/320 110/7206 0.00110842239806 ko04371 Apelin signaling pathway 18/320 177/7206 0.00112173784291 ko04971 Gastric acid secretion 12/320 98/7206 0.00125030631769 ko04068 FoxO signaling pathway 17/320 167/7206 0.00160276360488 ko05031 Amphetamine addiction 11/320 91/7206 0.00219436942579 ko04925 Aldosterone synthesis and secretion 12/320 105/7206 0.0022763007933 ko04152 AMPK signaling pathway 16/320 161/7206 0.00264386335069 ko04261 Adrenergic signaling in cardiomyocytes 19/320 205/7206 0.00267957350196 ko04970 Salivary secretion 11/320 95/7206 0.00309319319367 ko00680 Methane metabolism 6/320 34/7206 0.00343027068342 ko04014 Ras signaling pathway 23/320 279/7206 0.00420038034163 ko04922 Glucagon signaling pathway 13/320 128/7206 0.00432717066651 ko04726 Serotonergic synapse 14/320 137/7206 0.0048098875492 ko04722 Neurotrophin signaling pathway 15/320 160/7206 0.00547827114016 ko04919 Thyroid hormone signaling pathway 14/320 143/7206 0.00576492344954 ko05323 Rheumatoid arthritis 10/320 89/7206 0.00583747147835 ko00562 Inositol phosphate metabolism 10/320 89/7206 0.00583747147835 ko04145 Phagosome 15/320 162/7206 0.00601149119478 ko04140 Autophagy - animal 15/320 164/7206 0.00660677891229 ko05214 Glioma 9/320 79/7206 0.00798869526773 ko04964 Proximal tubule bicarbonate reclamation 5/320 29/7206 0.00825106650241 ko04740 Olfactory transduction 9/320 80/7206 0.00866091734808 ko04960 Aldosterone-regulated sodium reabsorption 6/320 41/7206 0.00884240959732 ko04114 Oocyte meiosis 13/320 139/7206 0.0103086792998 ko04022 cGMP-PKG signaling pathway 18/320 216/7206 0.0103864774836 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/320 191/7206 0.012191392301 ko04910 Insulin signaling pathway 15/320 172/7206 0.012689791738 ko04723 Retrograde endocannabinoid signaling 15/320 175/7206 0.0138149727868 ko05322 Systemic lupus erythematosus 1/320 151/7206 0.0150014137404 ko00010 Glycolysis / Gluconeogenesis 8/320 74/7206 0.0162988212501 ko04060 Cytokine-cytokine receptor interaction 2/320 191/7206 0.0184480765284 ko04072 Phospholipase D signaling pathway 16/320 197/7206 0.0202749808444 ko04360 Axon guidance 18/320 233/7206 0.0217810682435 ko00770 Pantothenate and CoA biosynthesis 3/320 14/7206 0.02192972944 ko04062 Chemokine signaling pathway 16/320 201/7206 0.0220956687079 ko03040 Spliceosome 1/320 145/7206 0.0222109393084 ko05010 Alzheimer's disease 16/320 202/7206 0.0226281352936 ko04139 Mitophagy - yeast 5/320 37/7206 0.0227064054406 ko04750 Inflammatory mediator regulation of TRP channels 11/320 122/7206 0.0230676921502 ko01040 Biosynthesis of unsaturated fatty acids 4/320 25/7206 0.0230745710732 ko04066 HIF-1 signaling pathway 11/320 123/7206 0.0239879063598 ko05168 Herpes simplex infection 2/320 182/7206 0.0259863107035 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 3/320 15/7206 0.0265298273742 ko04020 Calcium signaling pathway 19/320 265/7206 0.0333479208571 ko03013 RNA transport 2/320 166/7206 0.0348323273067 ko05033 Nicotine addiction 6/320 56/7206 0.0367971291476 ko00051 Fructose and mannose metabolism 5/320 42/7206 0.0370687304645 ko04973 Carbohydrate digestion and absorption 5/320 42/7206 0.0370687304645 ko04218 Cellular senescence 14/320 177/7206 0.0385455482392 ko05166 HTLV-I infection 6/320 292/7206 0.0414651115526 ko00564 Glycerophospholipid metabolism 9/320 99/7206 0.0420063461711 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/320 1/7206 0.0444074382458 ko03010 Ribosome 1/320 129/7206 0.0471372649969 ko05152 Tuberculosis 14/320 187/7206 0.0472960569994