ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	31/571	56/7206	2.87614480047e-20
ko05032	Morphine addiction	41/571	110/7206	2.86677967249e-18
ko04724	Glutamatergic synapse	48/571	152/7206	9.40059422668e-18
ko04744	Phototransduction	23/571	36/7206	2.69805676651e-17
ko04080	Neuroactive ligand-receptor interaction	85/571	423/7206	1.3609867251e-16
ko04727	GABAergic synapse	39/571	110/7206	1.46214923758e-16
ko04723	Retrograde endocannabinoid signaling	48/571	175/7206	4.8945264868e-15
ko04024	cAMP signaling pathway	60/571	279/7206	2.9028316844e-13
ko04728	Dopaminergic synapse	46/571	185/7206	9.33569329012e-13
ko04725	Cholinergic synapse	40/571	160/7206	2.53143021777e-11
ko04721	Synaptic vesicle cycle	27/571	80/7206	2.8882422421e-11
ko04713	Circadian entrainment	35/571	136/7206	1.95575486731e-10
ko04911	Insulin secretion	29/571	117/7206	1.8302506688e-08
ko04726	Serotonergic synapse	31/571	137/7206	5.85908779215e-08
ko04921	Oxytocin signaling pathway	39/571	209/7206	3.24229459649e-07
ko04261	Adrenergic signaling in cardiomyocytes	38/571	205/7206	5.43426704294e-07
ko04020	Calcium signaling pathway	43/571	265/7206	4.32399098126e-06
ko04742	Taste transduction	16/571	61/7206	1.37160751554e-05
ko04260	Cardiac muscle contraction	21/571	98/7206	2.00422939205e-05
ko05203	Viral carcinogenesis	6/571	277/7206	5.64403846195e-05
ko05031	Amphetamine addiction	19/571	91/7206	7.20736756506e-05
ko04010	MAPK signaling pathway	46/571	321/7206	7.33744559813e-05
ko04720	Long-term potentiation	20/571	99/7206	7.65234836245e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/571	79/7206	0.000115849523915
ko03040	Spliceosome	1/571	145/7206	0.000136081185446
ko05164	Influenza A	2/571	167/7206	0.000214421364042
ko04970	Salivary secretion	18/571	95/7206	0.00039950570805
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/571	14/7206	0.000416861249968
ko04072	Phospholipase D signaling pathway	30/571	197/7206	0.000428480088153
ko05030	Cocaine addiction	15/571	73/7206	0.000490126852527
ko05322	Systemic lupus erythematosus	2/571	151/7206	0.000645665134992
ko04060	Cytokine-cytokine receptor interaction	4/571	191/7206	0.000949820107967
ko04070	Phosphatidylinositol signaling system	19/571	112/7206	0.00124697514014
ko04141	Protein processing in endoplasmic reticulum	4/571	184/7206	0.00131727915869
ko05169	Epstein-Barr virus infection	5/571	206/7206	0.00145615575346
ko04514	Cell adhesion molecules (CAMs)	21/571	130/7206	0.0014933548671
ko04971	Gastric acid secretion	17/571	98/7206	0.00190002619913
ko05414	Dilated cardiomyopathy	18/571	112/7206	0.00384233241138
ko04110	Cell cycle	3/571	145/7206	0.00462465831418
ko04740	Olfactory transduction	14/571	80/7206	0.00502368317683
ko03013	RNA transport	4/571	166/7206	0.00509878541963
ko05162	Measles	2/571	120/7206	0.00567985998959
ko04964	Proximal tubule bicarbonate reclamation	7/571	29/7206	0.00632683059484
ko05014	Amyotrophic lateral sclerosis (ALS)	13/571	74/7206	0.00707786822231
ko04972	Pancreatic secretion	17/571	111/7206	0.00717825099689
ko04360	Axon guidance	30/571	233/7206	0.00894534192101
ko04730	Long-term depression	13/571	78/7206	0.0093001461589
ko04925	Aldosterone synthesis and secretion	16/571	105/7206	0.00974175491763
ko04022	cGMP-PKG signaling pathway	28/571	216/7206	0.00978368998244
ko04630	Jak-STAT signaling pathway	3/571	132/7206	0.0131992822144
ko05410	Hypertrophic cardiomyopathy (HCM)	15/571	100/7206	0.0140950499215
ko05205	Proteoglycans in cancer	11/571	271/7206	0.0153729956375
ko04350	TGF-beta signaling pathway	2/571	103/7206	0.0162607246484
ko04144	Endocytosis	39/571	342/7206	0.0181475374067
ko04120	Ubiquitin mediated proteolysis	4/571	138/7206	0.0245428515112
ko00310	Lysine degradation	1/571	73/7206	0.0286881032296
ko05130	Pathogenic Escherichia coli infection	1/571	77/7206	0.0301345898956
ko04612	Antigen processing and presentation	1/571	77/7206	0.0301345898956
ko05215	Prostate cancer	3/571	111/7206	0.0335640098117
ko05168	Herpes simplex infection	7/571	182/7206	0.0365143049381
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/571	182/7206	0.0365143049381
ko04960	Aldosterone-regulated sodium reabsorption	7/571	41/7206	0.0400906540845
ko04750	Inflammatory mediator regulation of TRP channels	16/571	122/7206	0.0410139631544
ko04924	Renin secretion	12/571	86/7206	0.0443689702615
ko05145	Toxoplasmosis	4/571	126/7206	0.0448345940725
ko04062	Chemokine signaling pathway	24/571	201/7206	0.0452908381573
ko05166	HTLV-I infection	14/571	292/7206	0.0456682933662
ko04218	Cellular senescence	7/571	177/7206	0.0477100155209
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/571	59/7206	0.0486595253554