ko pathway ratio_in_study ratio_in_pop p_value ko04728 Dopaminergic synapse 28/202 185/7206 1.37577737161e-13 ko05031 Amphetamine addiction 18/202 91/7206 4.19293064152e-11 ko04713 Circadian entrainment 21/202 136/7206 1.29920274945e-10 ko04724 Glutamatergic synapse 22/202 152/7206 1.68434962705e-10 ko05033 Nicotine addiction 14/202 56/7206 2.43023096721e-10 ko04911 Insulin secretion 18/202 117/7206 3.10540621553e-09 ko04721 Synaptic vesicle cycle 15/202 80/7206 4.11536447742e-09 ko04080 Neuroactive ligand-receptor interaction 35/202 423/7206 4.75399748217e-09 ko04727 GABAergic synapse 17/202 110/7206 8.09686218324e-09 ko04024 cAMP signaling pathway 26/202 279/7206 5.36688034764e-08 ko04725 Cholinergic synapse 19/202 160/7206 8.71603946982e-08 ko05030 Cocaine addiction 12/202 73/7206 6.95713325603e-07 ko05032 Morphine addiction 14/202 110/7206 2.0256395645e-06 ko04744 Phototransduction 8/202 36/7206 5.11412246881e-06 ko04720 Long-term potentiation 12/202 99/7206 1.84488478628e-05 ko04723 Retrograde endocannabinoid signaling 16/202 175/7206 2.88278210241e-05 ko05014 Amyotrophic lateral sclerosis (ALS) 9/202 74/7206 0.000204017269556 ko04921 Oxytocin signaling pathway 16/202 209/7206 0.000239741432267 ko04745 Phototransduction - fly 6/202 38/7206 0.000587856537946 ko04626 Plant-pathogen interaction 4/202 18/7206 0.00134668789181 ko04971 Gastric acid secretion 9/202 98/7206 0.0016286056314 ko04261 Adrenergic signaling in cardiomyocytes 14/202 205/7206 0.00178840851501 ko04925 Aldosterone synthesis and secretion 9/202 105/7206 0.00262860884054 ko05034 Alcoholism 15/202 238/7206 0.00374666645913 ko04010 MAPK signaling pathway 18/202 321/7206 0.00472918981418 ko04726 Serotonergic synapse 10/202 137/7206 0.00499351374022 ko04966 Collecting duct acid secretion 4/202 26/7206 0.0055220655491 ko04961 Endocrine and other factor-regulated calcium reabsorption 6/202 59/7206 0.00589727163235 ko04740 Olfactory transduction 7/202 80/7206 0.00690741632728 ko04964 Proximal tubule bicarbonate reclamation 4/202 29/7206 0.0082178616885 ko04924 Renin secretion 7/202 86/7206 0.0101551405534 ko04020 Calcium signaling pathway 15/202 265/7206 0.011497682248 ko04970 Salivary secretion 7/202 95/7206 0.0169356760085 ko04260 Cardiac muscle contraction 7/202 98/7206 0.0197762908007 ko04976 Bile secretion 6/202 80/7206 0.0243080049435 ko04978 Mineral absorption 4/202 40/7206 0.0249244441474 ko04960 Aldosterone-regulated sodium reabsorption 4/202 41/7206 0.0270314929477 ko04742 Taste transduction 5/202 61/7206 0.0275673801871 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/202 1/7206 0.0280321953928 ko04973 Carbohydrate digestion and absorption 4/202 42/7206 0.0292420639568 ko05016 Huntington's disease 1/202 215/7206 0.0323999590099 ko04972 Pancreatic secretion 7/202 111/7206 0.0359437501499 ko05323 Rheumatoid arthritis 6/202 89/7206 0.0383183002148 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/202 92/7206 0.0439350561913