ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	39/504	152/7206	3.71816077883e-13
ko05033	Nicotine addiction	23/504	56/7206	5.9278737806e-13
ko04727	GABAergic synapse	32/504	110/7206	1.29605269947e-12
ko05032	Morphine addiction	30/504	110/7206	4.05816760921e-11
ko04744	Phototransduction	17/504	36/7206	4.35993424712e-11
ko04725	Cholinergic synapse	35/504	160/7206	7.55135360669e-10
ko04728	Dopaminergic synapse	37/504	185/7206	3.45821050394e-09
ko04911	Insulin secretion	28/504	117/7206	4.76791549993e-09
ko04713	Circadian entrainment	30/504	136/7206	1.04001836109e-08
ko04080	Neuroactive ligand-receptor interaction	62/504	423/7206	1.14453424439e-08
ko04721	Synaptic vesicle cycle	22/504	80/7206	1.44160429967e-08
ko04723	Retrograde endocannabinoid signaling	34/504	175/7206	3.27552441608e-08
ko04024	cAMP signaling pathway	43/504	279/7206	8.34815299628e-07
ko04964	Proximal tubule bicarbonate reclamation	11/504	29/7206	1.91098766239e-06
ko04726	Serotonergic synapse	26/504	137/7206	2.23205444232e-06
ko04020	Calcium signaling pathway	40/504	265/7206	3.12999221641e-06
ko04970	Salivary secretion	19/504	95/7206	2.4206275279e-05
ko04261	Adrenergic signaling in cardiomyocytes	31/504	205/7206	3.70732307685e-05
ko04972	Pancreatic secretion	20/504	111/7206	7.18639052721e-05
ko04070	Phosphatidylinositol signaling system	20/504	112/7206	8.19157006029e-05
ko04971	Gastric acid secretion	18/504	98/7206	0.000126966022006
ko05322	Systemic lupus erythematosus	1/504	151/7206	0.000310856679307
ko04960	Aldosterone-regulated sodium reabsorption	10/504	41/7206	0.000397780270135
ko05203	Viral carcinogenesis	6/504	277/7206	0.000427390649027
ko03040	Spliceosome	1/504	145/7206	0.000723493144157
ko04072	Phospholipase D signaling pathway	26/504	197/7206	0.00155736117058
ko04921	Oxytocin signaling pathway	27/504	209/7206	0.00209045850017
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/504	59/7206	0.0022702502556
ko04010	MAPK signaling pathway	37/504	321/7206	0.00231546493005
ko04071	Sphingolipid signaling pathway	22/504	162/7206	0.00255719894968
ko04925	Aldosterone synthesis and secretion	16/504	105/7206	0.00287790639371
ko05030	Cocaine addiction	12/504	73/7206	0.00435946401725
ko05166	HTLV-I infection	9/504	292/7206	0.00472695903386
ko03013	RNA transport	3/504	166/7206	0.00487240336409
ko05164	Influenza A	3/504	167/7206	0.00495561411884
ko05031	Amphetamine addiction	14/504	91/7206	0.00533803541333
ko04120	Ubiquitin mediated proteolysis	2/504	138/7206	0.006022736122
ko04022	cGMP-PKG signaling pathway	26/504	216/7206	0.00616769331669
ko05168	Herpes simplex infection	4/504	182/7206	0.00724626519191
ko04973	Carbohydrate digestion and absorption	8/504	42/7206	0.00770270453961
ko04260	Cardiac muscle contraction	14/504	98/7206	0.00864635523895
ko04710	Circadian rhythm	8/504	43/7206	0.0089006029085
ko04742	Taste transduction	10/504	61/7206	0.00908639610599
ko04720	Long-term potentiation	14/504	99/7206	0.00931917698565
ko04014	Ras signaling pathway	31/504	279/7206	0.0112129786581
ko04930	Type II diabetes mellitus	9/504	54/7206	0.0117235529294
ko04976	Bile secretion	12/504	80/7206	0.0120904328116
ko05230	Central carbon metabolism in cancer	12/504	81/7206	0.0128176573522
ko04745	Phototransduction - fly	7/504	38/7206	0.0148489363228
ko04371	Apelin signaling pathway	21/504	177/7206	0.0159099267695
ko05169	Epstein-Barr virus infection	6/504	206/7206	0.0174511611403
ko04978	Mineral absorption	7/504	40/7206	0.0194521363139
ko04514	Cell adhesion molecules (CAMs)	16/504	130/7206	0.0231340283233
ko04621	NOD-like receptor signaling pathway	4/504	157/7206	0.0252061710245
ko00471	D-Glutamine and D-glutamate metabolism	2/504	4/7206	0.0266458750083
ko05205	Proteoglycans in cancer	10/504	271/7206	0.0281517161737
ko00680	Methane metabolism	6/504	34/7206	0.028557438628
ko04657	IL-17 signaling pathway	1/504	87/7206	0.0306970301395
ko04966	Collecting duct acid secretion	5/504	26/7206	0.031710287846
ko00562	Inositol phosphate metabolism	12/504	89/7206	0.0322285712308
ko05224	Breast cancer	5/504	174/7206	0.0332470834048
ko04062	Chemokine signaling pathway	22/504	201/7206	0.0341348285874
ko04360	Axon guidance	25/504	233/7206	0.035176681309
ko04810	Regulation of actin cytoskeleton	10/504	264/7206	0.0359998406485
ko05014	Amyotrophic lateral sclerosis (ALS)	10/504	74/7206	0.0368344779187
ko00910	Nitrogen metabolism	4/504	19/7206	0.0395272362442
ko04141	Protein processing in endoplasmic reticulum	6/504	184/7206	0.0402355420319
ko04110	Cell cycle	4/504	145/7206	0.0462216341723
ko05162	Measles	3/504	120/7206	0.0470217808671